Tumor-associated macrophages: role in cancer development and therapeutic implications

Background Tumor-associated macrophages (TAMs) are known to play important roles in the initiation and progression of human cancers, as well as in angiogenesis. TAMs are considered as main components of the tumor microenvironment. Targeting TAMs may serve as a therapeutic strategy for the treatment...

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Bibliographic Details
Published in:	Cellular oncology (Dordrecht) Vol. 42; no. 5; pp. 591 - 608
Main Authors:	Salmaninejad, Arash, Valilou, Saeed Farajzadeh, Soltani, Arash, Ahmadi, Sepideh, Abarghan, Yousef Jafari, Rosengren, Rhonda J., Sahebkar, Amirhossein
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer Netherlands 01.10.2019 Springer Nature B.V
Subjects:	Angiogenesis Biomedical and Life Sciences Biomedicine Cancer Cancer Research Cell Transformation, Neoplastic - metabolism Disease Progression Extravasation Humans Inflammation - immunology Inflammation - metabolism Macrophages Macrophages - immunology Macrophages - metabolism Metastases Metastasis Neoplasm Metastasis - drug therapy Neoplasm Metastasis - immunology Neoplasms - blood supply Neoplasms - immunology Neoplasms - metabolism Neoplasms - pathology Neovascularization, Pathologic - immunology Neovascularization, Pathologic - metabolism Oncology Pathology Review Signal Transduction - genetics Signal Transduction - immunology Tumor Microenvironment - immunology TAM Angiogenesis Targeted therapy Immunotherapy Metastasis Macrophage Cancer
ISSN:	2211-3428, 2211-3436, 2211-3436
Online Access:	Get full text
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