Evaluating multiple sclerosis severity loci 30 years after a clinically isolated syndrome

Abstract The first genome-wide significant multiple sclerosis severity locus, rs10191329, has been pathologically linked to cortical lesion load and brain atrophy. However, observational cohorts such as MSBase have not replicated associations with disability outcomes, instead finding other loci. We...

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Bibliographic Details

Published in:	Brain communications Vol. 6; no. 6; p. fcae443
Main Authors:	Sahi, Nitin, Haider, Lukas, Chung, Karen, Prados Carrasco, Ferran, Kanber, Baris, Samson, Rebecca, Thompson, Alan J, Trip, S Anand, Brownlee, Wallace, Ciccarelli, Olga, Barkhof, Frederik, Tur, Carmen, Houlden, Henry, Chard, Declan
Format:	Journal Article
Language:	English
Published:	UK Oxford University Press 2024
Subjects:	severity phenotype genetics disease progression multiple sclerosis
ISSN:	2632-1297, 2632-1297
Online Access:	Get full text
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