Effects of ellagitannin-rich berries on blood lipids, gut microbiota, and urolithin production in human subjects with symptoms of metabolic syndrome

Ellagitannins are polyphenols abundant in strawberries, raspberries, and cloudberries. The effects of a mixture of these berries were studied in a randomized controlled trial with subjects having symptoms of metabolic syndrome. The study focused on serum lipid profiles, gut microbiota, and ellagitan...

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Vydáno v:	Molecular nutrition & food research Ročník 57; číslo 12; s. 2258 - 2263
Hlavní autoři:	Puupponen-Pimiä, Riitta, Seppänen-Laakso, Tuulikki, Kankainen, Matti, Maukonen, Johanna, Törrönen, Riitta, Kolehmainen, Marjukka, Leppänen, Tiina, Moilanen, Eeva, Nohynek, Liisa, Aura, Anna-Marja, Poutanen, Kaisa, Tómas-Barberán, Francisco A., Espín, Juan C., Oksman-Caldentey, Kirsi-Marja
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Weinheim Blackwell Publishing Ltd 01.12.2013 Wiley
Témata:	Bioavailability Biological and medical sciences Blood Pressure - drug effects Clinical trial Coumarins - urine Ellagitannin-rich berries Feeding. Feeding behavior Fragaria Fruit - chemistry Fundamental and applied biological sciences. Psychology Gastrointestinal Tract - drug effects Gastrointestinal Tract - microbiology Humans Hydrolyzable Tannins - pharmacology Hydrolyzable Tannins - urine Lipidomics Lipids - blood Medical sciences Metabolic diseases Metabolic Syndrome - diet therapy Metabolic Syndrome - metabolism Metabolic Syndrome - microbiology Microbiological profiling Microbiota Miscellaneous Other metabolic disorders Treatment Outcome Urolithins Vertebrates: anatomy and physiology, studies on body, several organs or systems Endocrinopathy Human Biological fluid Fruit Nutrition Microbiological profiling Berry Gut Metabolic diseases Cardiovascular disease Lipids Microflora Ellagitannin-rich berries Lipidomics Metabolic syndrome Blood Symptomatology Microbiological investigation Urolithins Plant origin Production Clinical trial
ISSN:	1613-4125, 1613-4133, 1613-4133
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Shrnutí:	Ellagitannins are polyphenols abundant in strawberries, raspberries, and cloudberries. The effects of a mixture of these berries were studied in a randomized controlled trial with subjects having symptoms of metabolic syndrome. The study focused on serum lipid profiles, gut microbiota, and ellagitannin metabolites. The results indicate that bioavailability of ellagitannins appears to be dependent on the composition of gut microbiota.
Bibliografie:	ark:/67375/WNG-TL2CGPN4-5 Technology and Innovation (Tekes) - No. 40361/05 istex:E752C7B0FA8C5DEAB96C487C761498B41352AE9F ArticleID:MNFR2046 This study is registered at as NCT01414647. ClinicalTrials.gov ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Undefined-3 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	1613-4125 1613-4133 1613-4133
DOI:	10.1002/mnfr.201300280