Intracellular infections enhance interleukin-6 and plasminogen activator inhibitor 1 production by cocultivated human adipocytes and THP-1 monocytes

Obesity is associated with a chronic inflammatory state, and adipocyte dysfunction is thought to play a crucial role in this. Infection of adipose tissue may trigger the production of inflammatory cytokines, leading to increased recruitment of macrophages into adipose tissue, which in turn may exace...

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Bibliographic Details

Published in:	Clinical and vaccine immunology Vol. 16; no. 8; p. 1222
Main Authors:	Bouwman, J J M, Diepersloot, R J A, Visseren, F L J
Format:	Journal Article
Language:	English
Published:	United States 01.08.2009
Subjects:	Adenoviridae - immunology Adipocytes - immunology Adiponectin - biosynthesis Cells, Cultured Coculture Techniques Cytomegalovirus - immunology Humans Influenza A virus - immunology Interleukin-6 - biosynthesis Monocytes - immunology Plasminogen Activator Inhibitor 1 - biosynthesis Tumor Necrosis Factor-alpha - biosynthesis Up-Regulation
ISSN:	1556-679X, 1556-679X
Online Access:	Get more information
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