Optimizing the Ion-Optical Design of a Portable Static Mass Spectrometer for Medical Diagnostics

We propose the design of a compact Mattauch–Herzog ion-optical system featuring a double-focusing static mass spectrometer with a cylindrical electrostatic deflector. This system offers second-order angle focusing and first-order energy focusing along the focal line. The collimating system ensures t...

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Vydáno v:Journal of analytical chemistry (New York, N.Y.) Ročník 78; číslo 13; s. 1868 - 1873
Hlavní autoři: Antonov, A. S., Aruev, N. N., Kuleshov, D. O., Sachenko, V. D.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Moscow Pleiades Publishing 01.12.2023
Springer
Springer Nature B.V
Témata:
Analytical Chemistry
Approximation
Biomarkers
Chemistry
Chemistry and Materials Science
Design
Design and construction
Design optimization
Diagnostic equipment (Medical)
diagnostic techniques
energy
Ion beams
Magnetic fields
Mass spectrometers
Mathematical optimization
Optical design
spectrometers
Russia
Mattauch–Herzog geometry
mass spectrograph
static mass spectrometer
small-size mass spectrometer
static mass analyzer
ISSN:1061-9348, 1608-3199
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Popis
Shrnutí:We propose the design of a compact Mattauch–Herzog ion-optical system featuring a double-focusing static mass spectrometer with a cylindrical electrostatic deflector. This system offers second-order angle focusing and first-order energy focusing along the focal line. The collimating system ensures the optimal vertical acceptance of the mass analyzer and maximum ion transmission within the working mass range. The described ion-optical system serves as a foundation for small-sized mass spectrometers, weighing up to ~50 kg, including turbo-molecular and foreline pumps, while maintaining high analytical performance.
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ISSN:1061-9348
1608-3199
DOI:10.1134/S1061934823130026