The (I/Y)XGG motif of adenovirus DNA polymerase affects template DNA binding and the transition from initiation to elongation

Adenovirus DNA polymerase (Ad pol) is a eukaryotic-type DNA polymerase involved in the catalysis of protein-primed initiation as well as DNA polymerization. The functional significance of the (I/Y)XGG motif, highly conserved among eukaryotic-type DNA polymerases, was analyzed in Ad pol by site-direc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry Jg. 276; H. 32; S. 29846
Hauptverfasser:	Brenkman, A B, Heideman, M R, Truniger, V, Salas, M, van der Vliet, P C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 10.08.2001
Schlagworte:	Adenoviridae - enzymology Amino Acid Motifs Amino Acid Sequence Amino Acids - chemistry Binding Sites Catalysis DNA - metabolism DNA Mutational Analysis DNA-Binding Proteins - metabolism DNA-Directed DNA Polymerase - chemistry Dose-Response Relationship, Drug Glycerol - pharmacology Kinetics Molecular Sequence Data Mutagenesis, Site-Directed Mutation Protein Binding
ISSN:	0021-9258
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!