Boron-containing aptamers to ATP

Boron neutron capture therapy (BNCT), an experimental treatment for certain cancers, destroys only cells near the boron; however, there is a need to develop highly specific delivery agents. As nucleic acid aptamers recognize specific molecular targets, we investigated the influence of boronated nucl...

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Bibliographic Details
Published in:	Nucleic acids research Vol. 30; no. 6; pp. 1401 - 1407
Main Author:	Lato, S. M.
Format:	Journal Article
Language:	English
Published:	England Oxford Publishing Limited (England) 15.03.2002 Oxford University Press
Subjects:	Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - metabolism aptamers ATP Base Sequence Binding Sites Boron Boron - chemistry Boron Neutron Capture Therapy Directed Molecular Evolution Molecular Sequence Data Neoplasms - radiotherapy Nucleic Acid Conformation Nucleic acids Oligoribonucleotides - chemistry Oligoribonucleotides - metabolism Sequence Alignment
ISSN:	1362-4962, 0305-1048, 1362-4962
Online Access:	Get full text
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