Pulmonary monocytes interact with effector T cells in the lung tissue to drive TRM differentiation following viral infection

Lung resident memory CD8 T cells (TRM) are critical for protection against respiratory viruses, but the cellular interactions required for their development are poorly understood. Herein we describe the necessity of classical monocytes for the establishment of lung TRM following influenza infection....

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Bibliographic Details
Published in:	Mucosal immunology Vol. 13; no. 1; pp. 161 - 171
Main Authors:	Dunbar, Paul R., Cartwright, Emily K., Wein, Alexander N., Tsukamoto, Tetsuo, Tiger Li, Zheng-Rong, Kumar, Nivedha, Uddbäck, Ida E., Hayward, Sarah L., Ueha, Satoshi, Takamura, Shiki, Kohlmeier, Jacob E.
Format:	Journal Article
Language:	English
Published:	New York Elsevier Inc 01.01.2020 Nature Publishing Group US Elsevier Limited
Subjects:	Allergology Antibodies Antigen-presenting cells Antigens Antiviral drugs Biomedical and Life Sciences Biomedicine CCR2 protein CD8 antigen Cell differentiation Dendritic cells Effector cells Gastroenterology Immunological memory Immunology Infections Influenza Lungs Lymphocytes Lymphocytes T Memory cells Monocyte chemoattractant protein 1 Monocytes
ISSN:	1933-0219, 1935-3456, 1935-3456
Online Access:	Get full text
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