Tumor inhibition or tumor promotion? The duplicity of CXCR3 in cancer

Tumor tissue includes cancer cells and normal stromal cells such as vascular endothelial cells, connective tissue cells (cancer associated fibroblast, mesenchymal stem cell), and immune cells (tumor‐infiltrating lymphocytes or TIL, dendritic cells, eosinophils, basophils, mast cells, tumor‐associate...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 108; no. 2; pp. 673 - 685
Main Authors:	Russo, Eleonora, Santoni, Angela, Bernardini, Giovanni
Format:	Journal Article
Language:	English
Published:	United States Oxford University Press 01.08.2020
Subjects:	Animals anti‐tumor immunity Biomarkers Cancer cancer immunotherapy CD8 antigen Cell activation Cell survival Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Chemokines Connective tissues CXCL10 CXCL10 protein CXCL11 protein CXCR3 protein Dendritic cells Disease Susceptibility Endothelial cells Eosinophils Gene Duplication Gene Expression Regulation, Neoplastic Homeostasis Humans Immune response immune suppression Immune system Immunomodulation Immunotherapy Inflammation Leukocytes (basophilic) Leukocytes (eosinophilic) Ligands lymphocyte migration Lymphocytes Lymphocytes T Macrophages Mast cells Mesenchymal stem cells Metastases Molecular modelling Natural killer cells Neoplasms - etiology Neoplasms - metabolism Neoplasms - pathology Protein Binding Receptors, CXCR3 - genetics Receptors, CXCR3 - metabolism Signal Transduction Solid tumors Stem cells Stromal cells Tumors CXCL10 anti-tumor immunity chemokines immune suppression cancer immunotherapy lymphocyte migration
ISSN:	0741-5400, 1938-3673, 1938-3673
Online Access:	Get full text
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