Evaluation of hydro-alcoholic extract of Eclipta alba for its anticancer potential: An in vitro study

Eclipta alba is traditionally used as hepatoprotective agent. The study was designed to explore its antiproliferative activity on liver and other related cancer. The present study was designed to assess and establish the role of Eclipta alba as anti-cancer agent using HepG2, C6 glioma and A498 cell...

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Bibliographic Details
Published in:	Journal of ethnopharmacology Vol. 136; no. 2; pp. 363 - 367
Main Authors:	Chaudhary, Harshita, Dhuna, Vikram, Singh, Jatinder, Kamboj, Sukhdev Singh, Seshadri, Sriram
Format:	Journal Article
Language:	English
Published:	Shannon Elsevier B.V 22.06.2011 Elsevier Ireland Ltd Elsevier
Subjects:	Anti-metastasis Antineoplastic Agents, Phytogenic Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic Agents, Phytogenic - therapeutic use apoptosis Apoptosis - drug effects Apoptotic Biological and medical sciences Cell Line, Tumor cell proliferation Cell Proliferation - drug effects cytotoxicity DNA Damage Down-Regulation drug effects drug therapy Eclipta Eclipta alba Eclipta prostrata gelatin General pharmacology Glioma Glioma - drug therapy Glioma - metabolism Hep G2 Cells Hepatoblastoma Hepatoblastoma - drug therapy Hepatoblastoma - metabolism Humans in vitro studies Inhibitory Concentration 50 liver Liver Neoplasms Liver Neoplasms - drug therapy Liver Neoplasms - metabolism Matrix Metalloproteinases Matrix Metalloproteinases - metabolism Medical sciences metabolism metalloproteinases Neoplasms Neoplasms - drug therapy Neoplasms - metabolism NF-kappa B NF-kappa B - metabolism NF-kB Pharmacognosy. Homeopathy. Health food pharmacology Pharmacology. Drug treatments Phytotherapy Plant Extracts Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves polymerase chain reaction therapeutic use Western blotting Matrix metalloproteinases Anti-metastasis Eclipta alba Apoptotic NF-kB Antineoplastic agent Evaluation Enzyme Pharmacognosy Metalloendopeptidases Extract Malignant tumor Metastasis In vitro Medicinal plant Peptidases Plant origin Hydrolases Cancer
ISSN:	0378-8741, 1872-7573, 1872-7573
Online Access:	Get full text
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