Multidrug Resistance in Cancer: Understanding Molecular Mechanisms, Immunoprevention and Therapeutic Approaches

Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer....

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Frontiers in oncology Ročník 12; s. 891652
Hlavní autoři: Emran, Talha Bin, Shahriar, Asif, Mahmud, Aar Rafi, Rahman, Tanjilur, Abir, Mehedy Hasan, Siddiquee, Mohd. Faijanur - Rob, Ahmed, Hossain, Rahman, Nova, Nainu, Firzan, Wahyudin, Elly, Mitra, Saikat, Dhama, Kuldeep, Habiballah, Mahmoud M., Haque, Shafiul, Islam, Ariful, Hassan, Mohammad Mahmudul
Médium: Journal Article
Jazyk:angličtina
Vydáno: Frontiers Media S.A 23.06.2022
Témata:
cancer
immuno-prevention
intracellular and extracellular ATP
microRNA
multidrug resistance
Oncology
ISSN:2234-943X, 2234-943X
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Abstract Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer. This review describes the known MDR mechanisms in cancer cells and discusses ongoing laboratory approaches and novel therapeutic strategies that aim to inhibit, circumvent, or reverse MDR development in various cancer types. In this review, we discuss both intrinsic and acquired drug resistance, in addition to highlighting hypoxia- and autophagy-mediated drug resistance mechanisms. Several factors, including individual genetic differences, such as mutations, altered epigenetics, enhanced drug efflux, cell death inhibition, and various other molecular and cellular mechanisms, are responsible for the development of resistance against anticancer agents. Drug resistance can also depend on cellular autophagic and hypoxic status. The expression of drug-resistant genes and the regulatory mechanisms that determine drug resistance are also discussed. Methods to circumvent MDR, including immunoprevention, the use of microparticles and nanomedicine might result in better strategies for fighting cancer.
AbstractList Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer. This review describes the known MDR mechanisms in cancer cells and discusses ongoing laboratory approaches and novel therapeutic strategies that aim to inhibit, circumvent, or reverse MDR development in various cancer types. In this review, we discuss both intrinsic and acquired drug resistance, in addition to highlighting hypoxia- and autophagy-mediated drug resistance mechanisms. Several factors, including individual genetic differences, such as mutations, altered epigenetics, enhanced drug efflux, cell death inhibition, and various other molecular and cellular mechanisms, are responsible for the development of resistance against anticancer agents. Drug resistance can also depend on cellular autophagic and hypoxic status. The expression of drug-resistant genes and the regulatory mechanisms that determine drug resistance are also discussed. Methods to circumvent MDR, including immunoprevention, the use of microparticles and nanomedicine might result in better strategies for fighting cancer.
Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer. This review describes the known MDR mechanisms in cancer cells and discusses ongoing laboratory approaches and novel therapeutic strategies that aim to inhibit, circumvent, or reverse MDR development in various cancer types. In this review, we discuss both intrinsic and acquired drug resistance, in addition to highlighting hypoxia- and autophagy-mediated drug resistance mechanisms. Several factors, including individual genetic differences, such as mutations, altered epigenetics, enhanced drug efflux, cell death inhibition, and various other molecular and cellular mechanisms, are responsible for the development of resistance against anticancer agents. Drug resistance can also depend on cellular autophagic and hypoxic status. The expression of drug-resistant genes and the regulatory mechanisms that determine drug resistance are also discussed. Methods to circumvent MDR, including immunoprevention, the use of microparticles and nanomedicine might result in better strategies for fighting cancer.Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective against multidrug-resistant cancer. Multidrug resistance (MDR) represents a major obstacle to effective therapeutic interventions against cancer. This review describes the known MDR mechanisms in cancer cells and discusses ongoing laboratory approaches and novel therapeutic strategies that aim to inhibit, circumvent, or reverse MDR development in various cancer types. In this review, we discuss both intrinsic and acquired drug resistance, in addition to highlighting hypoxia- and autophagy-mediated drug resistance mechanisms. Several factors, including individual genetic differences, such as mutations, altered epigenetics, enhanced drug efflux, cell death inhibition, and various other molecular and cellular mechanisms, are responsible for the development of resistance against anticancer agents. Drug resistance can also depend on cellular autophagic and hypoxic status. The expression of drug-resistant genes and the regulatory mechanisms that determine drug resistance are also discussed. Methods to circumvent MDR, including immunoprevention, the use of microparticles and nanomedicine might result in better strategies for fighting cancer.
Author Nainu, Firzan
Hassan, Mohammad Mahmudul
Wahyudin, Elly
Dhama, Kuldeep
Rahman, Tanjilur
Rahman, Nova
Mahmud, Aar Rafi
Emran, Talha Bin
Abir, Mehedy Hasan
Ahmed, Hossain
Mitra, Saikat
Shahriar, Asif
Haque, Shafiul
Siddiquee, Mohd. Faijanur - Rob
Islam, Ariful
Habiballah, Mahmoud M.
AuthorAffiliation 9 Department of Biochemistry and Molecular Biology, Jahangirnagar University , Dhaka , Bangladesh
10 Department of Pharmacy, Faculty of Pharmacy, Hasanuddin University , Makassar , Indonesia
3 Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley , McAllen, TX , United States
7 Department of Biochemistry and Molecular Biology, University of Dhaka , Dhaka , Bangladesh
14 SMIRES for Consultation in Specialized Medical Laboratories, Jazan University , Jazan , Saudi Arabia
12 Division of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly , India
15 Research and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University , Jazan , Saudi Arabia
19 Department of Physiology, Biochemistry and Pharmacology, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University , Chattogram , Bangladesh
11 Department of Pharmacy, Faculty of Pharmacy, University of Dhaka , Dhaka , Bangladesh
18 Queensland
AuthorAffiliation_xml – name: 5 Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Chittagong , Chittagong , Bangladesh
– name: 12 Division of Pathology, ICAR-Indian Veterinary Research Institute , Bareilly , India
– name: 10 Department of Pharmacy, Faculty of Pharmacy, Hasanuddin University , Makassar , Indonesia
– name: 15 Research and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University , Jazan , Saudi Arabia
– name: 9 Department of Biochemistry and Molecular Biology, Jahangirnagar University , Dhaka , Bangladesh
– name: 4 Department of Biochemistry and Molecular Biology, Mawlana Bhashani Science and Technology University , Tangail , Bangladesh
– name: 6 Faculty of Food Science and Technology, Chattogram Veterinary and Animal Sciences University , Chattogram , Bangladesh
– name: 14 SMIRES for Consultation in Specialized Medical Laboratories, Jazan University , Jazan , Saudi Arabia
– name: 2 Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University , Dhaka , Bangladesh
– name: 18 Queensland Alliance for One Health Sciences, School of Veterinary Science, The University of Queensland , Gatton, QLD , Australia
– name: 7 Department of Biochemistry and Molecular Biology, University of Dhaka , Dhaka , Bangladesh
– name: 17 EcoHealth Alliance , New York, NY , United States
– name: 19 Department of Physiology, Biochemistry and Pharmacology, Faculty of Veterinary Medicine, Chattogram Veterinary and Animal Sciences University , Chattogram , Bangladesh
– name: 1 Department of Pharmacy, BGC Trust University Bangladesh , Chittagong , Bangladesh
– name: 11 Department of Pharmacy, Faculty of Pharmacy, University of Dhaka , Dhaka , Bangladesh
– name: 13 Medical Laboratory Technology Department, Jazan University , Jazan , Saudi Arabia
– name: 8 Department of Biotechnology and Genetic Engineering, University of Development Alternative , Dhaka , Bangladesh
– name: 3 Department of Immunology and Microbiology, School of Medicine, University of Texas Rio Grande Valley , McAllen, TX , United States
– name: 16 Bursa Uludağ University Faculty of Medicine , Bursa , Turkey
Author_xml – sequence: 1
  givenname: Talha Bin
  surname: Emran
  fullname: Emran, Talha Bin
– sequence: 2
  givenname: Asif
  surname: Shahriar
  fullname: Shahriar, Asif
– sequence: 3
  givenname: Aar Rafi
  surname: Mahmud
  fullname: Mahmud, Aar Rafi
– sequence: 4
  givenname: Tanjilur
  surname: Rahman
  fullname: Rahman, Tanjilur
– sequence: 5
  givenname: Mehedy Hasan
  surname: Abir
  fullname: Abir, Mehedy Hasan
– sequence: 6
  givenname: Mohd. Faijanur - Rob
  surname: Siddiquee
  fullname: Siddiquee, Mohd. Faijanur - Rob
– sequence: 7
  givenname: Hossain
  surname: Ahmed
  fullname: Ahmed, Hossain
– sequence: 8
  givenname: Nova
  surname: Rahman
  fullname: Rahman, Nova
– sequence: 9
  givenname: Firzan
  surname: Nainu
  fullname: Nainu, Firzan
– sequence: 10
  givenname: Elly
  surname: Wahyudin
  fullname: Wahyudin, Elly
– sequence: 11
  givenname: Saikat
  surname: Mitra
  fullname: Mitra, Saikat
– sequence: 12
  givenname: Kuldeep
  surname: Dhama
  fullname: Dhama, Kuldeep
– sequence: 13
  givenname: Mahmoud M.
  surname: Habiballah
  fullname: Habiballah, Mahmoud M.
– sequence: 14
  givenname: Shafiul
  surname: Haque
  fullname: Haque, Shafiul
– sequence: 15
  givenname: Ariful
  surname: Islam
  fullname: Islam, Ariful
– sequence: 16
  givenname: Mohammad Mahmudul
  surname: Hassan
  fullname: Hassan, Mohammad Mahmudul
BookMark eNp1UU1r3DAQNSWlSdPce9Sxh-5WX5alHgph6cdClkJJoDcxK493FWzJlexA_33lbihNobpoGL335o3ey-osxIBV9ZrRtRDavOticGtOOV9rw1TNn1UXnAu5MlJ8P_urPq-ucr6n5aiaMipeVOei1kxKUV9UcTf3k2_TfCDfMPs8QXBIfCCbpUjvyV1oMS3t1ocD2cUe3dxDIjt0Rwg-D_kt2Q7DHOKY8AHD5GMgBU1uj5hgxHnyjlyPY4rgjphfVc876DNePd6X1d2nj7ebL6ubr5-3m-ublZPCTKt97YBzCaA70QpsHOsER74HJYpx2TLmpDTcUKOZwka0jILSKGpQxnVYi8tqe9JtI9zbMfkB0k8bwdvfjZgOFlKx1qPttOGNMoZJ10jomj3KTjkhyyeLvVRQtD6ctMZ5P2DrypIJ-ieiT1-CP9pDfLCGq7KELgJvHgVS_DFjnuzgs8O-h4BxzpYrralumOIFSk9Ql2LOCbs_Yxi1S-x2id0usdtT7IWi_qE4P8GSQzHj-_8TfwEaLLWJ
CitedBy_id crossref_primary_10_1002_ardp_202300704
crossref_primary_10_1186_s13046_025_03389_5
crossref_primary_10_3390_nu16060797
crossref_primary_10_3390_cancers16040680
crossref_primary_10_1002_pro_5108
crossref_primary_10_1186_s12645_024_00297_9
crossref_primary_10_1002_slct_202303591
crossref_primary_10_3390_cancers15153942
crossref_primary_10_1016_j_fitote_2025_106607
crossref_primary_10_1016_j_ijpharm_2025_125729
crossref_primary_10_1186_s12885_024_12718_4
crossref_primary_10_1016_j_bcp_2025_116828
crossref_primary_10_1016_j_cellsig_2024_111329
crossref_primary_10_1016_j_jddst_2024_105768
crossref_primary_10_1186_s12935_023_03004_7
crossref_primary_10_1016_j_omtn_2024_102177
crossref_primary_10_1016_j_puhe_2025_105914
crossref_primary_10_1134_S1070363224050177
crossref_primary_10_3390_biomedicines11020389
crossref_primary_10_1002_jbt_70137
crossref_primary_10_3389_fphar_2025_1631232
crossref_primary_10_7717_peerj_18733
crossref_primary_10_1016_j_jsbmb_2025_106832
crossref_primary_10_3390_antibiotics13090911
crossref_primary_10_3390_ijms25147607
crossref_primary_10_1002_path_6384
crossref_primary_10_1177_20503121241292673
crossref_primary_10_1016_j_jtbi_2025_112048
crossref_primary_10_1080_1061186X_2024_2365934
crossref_primary_10_1089_ars_2023_0491
crossref_primary_10_1016_j_biomaterials_2024_122710
crossref_primary_10_1016_j_drudis_2025_104339
crossref_primary_10_1089_dna_2023_0048
crossref_primary_10_1038_s41598_025_92495_7
crossref_primary_10_1111_cas_16097
crossref_primary_10_1186_s12885_024_12481_6
crossref_primary_10_1016_j_heliyon_2024_e39229
crossref_primary_10_1016_j_bbcan_2023_189015
crossref_primary_10_3389_fimmu_2022_1070367
crossref_primary_10_3390_metabo15020136
crossref_primary_10_1016_j_prp_2024_155457
crossref_primary_10_32604_or_2022_027547
crossref_primary_10_1002_bit_28561
crossref_primary_10_1093_bib_bbae300
crossref_primary_10_1080_17568919_2025_2485675
crossref_primary_10_1039_D5DT00471C
crossref_primary_10_1016_j_compbiomed_2024_109415
crossref_primary_10_3390_medicines10060036
crossref_primary_10_1177_09731296251355768
crossref_primary_10_3390_cancers15194839
crossref_primary_10_3390_cancers17162628
crossref_primary_10_1002_cbin_12098
crossref_primary_10_1038_s41598_024_79948_1
crossref_primary_10_3390_plants12193479
crossref_primary_10_1038_s41598_025_94373_8
crossref_primary_10_3390_genes15040478
crossref_primary_10_1016_j_cbi_2024_111055
crossref_primary_10_3390_pharmaceutics17030296
crossref_primary_10_1134_S1070363223080194
crossref_primary_10_3390_cancers17050788
crossref_primary_10_1038_s41598_025_97786_7
crossref_primary_10_1016_j_prp_2023_154999
crossref_primary_10_1002_1878_0261_13640
crossref_primary_10_1002_smll_202307462
crossref_primary_10_1016_j_prp_2023_154756
crossref_primary_10_1002_slct_202301394
crossref_primary_10_3389_fonc_2024_1353800
crossref_primary_10_1080_14756366_2025_2507670
crossref_primary_10_3390_cimb47090749
crossref_primary_10_34133_bmef_0144
crossref_primary_10_3390_ijms232416098
crossref_primary_10_2174_0115748855284405231212051251
crossref_primary_10_1016_j_ejmech_2023_115495
crossref_primary_10_3390_pharmaceutics17010114
crossref_primary_10_4236_jbm_2025_135019
crossref_primary_10_1002_adtp_202400070
crossref_primary_10_1016_j_fitote_2025_106711
crossref_primary_10_1134_S1070363223100195
crossref_primary_10_3390_cancers17060979
crossref_primary_10_3390_life13112205
crossref_primary_10_1002_cbf_4075
crossref_primary_10_1007_s12094_024_03700_4
crossref_primary_10_1021_acsami_5c13063
crossref_primary_10_1038_s41423_024_01232_z
crossref_primary_10_3390_ijms24129984
crossref_primary_10_3390_pharmaceutics16070874
crossref_primary_10_1016_j_canlet_2024_217019
crossref_primary_10_1002_wnan_1984
crossref_primary_10_1016_j_canlet_2025_217536
crossref_primary_10_1016_j_canlet_2025_217783
crossref_primary_10_1016_j_dsx_2024_103048
crossref_primary_10_3390_molecules29173994
crossref_primary_10_1080_08830185_2025_2545364
crossref_primary_10_3390_ph17070922
crossref_primary_10_1134_S0006297924140086
crossref_primary_10_2174_0127724328335492241206075509
crossref_primary_10_3389_fcell_2024_1462339
crossref_primary_10_1007_s44187_024_00171_y
crossref_primary_10_1080_17435889_2024_2403962
crossref_primary_10_3390_microorganisms12020238
crossref_primary_10_3389_fgeed_2024_1342193
crossref_primary_10_1007_s11051_025_06233_1
crossref_primary_10_1016_j_matbio_2023_03_002
crossref_primary_10_1016_j_jddst_2025_106812
crossref_primary_10_1007_s12011_023_03803_z
crossref_primary_10_1016_j_isci_2025_112801
crossref_primary_10_3390_vaccines12121341
crossref_primary_10_1016_j_gene_2025_149636
crossref_primary_10_1007_s12672_025_02368_8
crossref_primary_10_3390_ijms252111346
crossref_primary_10_1038_s41598_024_81392_0
crossref_primary_10_3390_pharmaceutics17060751
crossref_primary_10_1007_s12032_025_02611_w
crossref_primary_10_3390_antiox12061268
crossref_primary_10_3390_biomedicines11051384
crossref_primary_10_1016_j_addr_2025_115685
crossref_primary_10_3390_cancers16040816
crossref_primary_10_1007_s42250_025_01224_0
crossref_primary_10_3390_molecules28196950
crossref_primary_10_1021_acs_nanolett_5c00617
crossref_primary_10_3390_ijms25074072
crossref_primary_10_3389_fbioe_2025_1548588
crossref_primary_10_1016_j_biomaterials_2025_123164
crossref_primary_10_1111_cbdd_14222
crossref_primary_10_1002_slct_202400225
crossref_primary_10_1016_j_intimp_2025_115537
crossref_primary_10_1134_S1070363224040273
crossref_primary_10_32604_or_2024_031006
crossref_primary_10_3390_ph17050576
crossref_primary_10_3892_or_2024_8739
crossref_primary_10_1134_S1070363223110294
crossref_primary_10_1186_s12967_024_05794_4
crossref_primary_10_4155_fmc_2023_0138
crossref_primary_10_1007_s12032_024_02580_6
crossref_primary_10_1038_s41540_024_00397_7
crossref_primary_10_1016_j_bioorg_2023_106496
crossref_primary_10_1002_cbf_3850
crossref_primary_10_1016_j_tranon_2024_102250
crossref_primary_10_1080_00914037_2025_2558674
crossref_primary_10_1080_17568919_2025_2515818
crossref_primary_10_1016_j_drudis_2024_104061
crossref_primary_10_1016_j_bbadis_2025_167821
crossref_primary_10_1016_j_jbc_2024_107994
crossref_primary_10_1080_10426507_2024_2419634
crossref_primary_10_1007_s12013_024_01626_w
crossref_primary_10_3389_fcell_2024_1500880
crossref_primary_10_1002_iub_2888
crossref_primary_10_1016_j_jddst_2024_106084
crossref_primary_10_1080_13543776_2023_2265561
crossref_primary_10_3390_ijms25031712
crossref_primary_10_1016_j_carpta_2025_100708
crossref_primary_10_1038_s41419_023_05963_1
crossref_primary_10_1039_D4MD00302K
crossref_primary_10_3390_ijms25137470
crossref_primary_10_1038_s41598_024_56197_w
crossref_primary_10_1007_s10989_024_10648_0
crossref_primary_10_1134_S0026893324060050
crossref_primary_10_1016_j_talanta_2023_124564
crossref_primary_10_1186_s12885_024_12775_9
crossref_primary_10_1016_j_drup_2025_101294
crossref_primary_10_1038_s41568_023_00612_3
crossref_primary_10_1007_s00210_024_03408_w
crossref_primary_10_1016_j_jep_2024_118187
crossref_primary_10_3390_ijms26157119
crossref_primary_10_32604_or_2024_053337
crossref_primary_10_1007_s42250_024_01163_2
crossref_primary_10_3390_ijms26146580
crossref_primary_10_1016_j_phytochem_2023_113867
crossref_primary_10_1016_j_inoche_2023_110830
crossref_primary_10_3390_ijms26051885
crossref_primary_10_1080_17568919_2025_2504336
crossref_primary_10_3390_nu16213741
crossref_primary_10_1016_j_yexcr_2025_114580
crossref_primary_10_3390_ijms26062534
crossref_primary_10_3390_ijtm5010006
crossref_primary_10_3390_molecules29163920
crossref_primary_10_1007_s10637_025_01562_3
crossref_primary_10_2174_0109298673283936240215110627
crossref_primary_10_3390_pharmaceutics16050654
crossref_primary_10_3390_cancers16162924
crossref_primary_10_3390_ijms252212402
crossref_primary_10_1016_j_bbadis_2025_167680
crossref_primary_10_3390_cancers15133399
crossref_primary_10_1002_ptr_8131
crossref_primary_10_1080_20415990_2024_2394012
crossref_primary_10_1134_S1070363223030180
crossref_primary_10_3390_nano15151139
crossref_primary_10_3390_ph18010072
crossref_primary_10_1002_cbf_4134
crossref_primary_10_1186_s12645_025_00321_6
crossref_primary_10_3390_biomedicines12010183
crossref_primary_10_1016_j_ejmech_2023_115879
crossref_primary_10_1080_20415990_2024_2442301
crossref_primary_10_1007_s12032_025_03029_0
crossref_primary_10_1016_j_jmb_2025_168979
crossref_primary_10_1515_jcim_2023_0182
crossref_primary_10_3390_ph17030361
crossref_primary_10_3390_ijms25116181
crossref_primary_10_3390_ijms26072923
crossref_primary_10_1002_ardp_70067
crossref_primary_10_1186_s12935_024_03558_0
crossref_primary_10_1002_ddr_70155
crossref_primary_10_1177_11779322251316864
crossref_primary_10_3390_molecules29132997
crossref_primary_10_3390_ph16101437
crossref_primary_10_3390_pharmaceutics17020201
crossref_primary_10_1016_j_pupt_2024_102317
crossref_primary_10_1002_cbdv_202502012
crossref_primary_10_1038_s41598_025_16195_y
crossref_primary_10_1177_09731296251318787
crossref_primary_10_3389_fmolb_2025_1616221
crossref_primary_10_1007_s00204_024_03861_9
crossref_primary_10_1016_j_ijpharm_2023_123276
crossref_primary_10_1016_j_ejps_2025_107235
crossref_primary_10_1002_ardp_202300651
crossref_primary_10_1007_s12668_024_01532_8
crossref_primary_10_1016_j_bbcan_2025_189441
crossref_primary_10_3390_pharmaceutics15020584
crossref_primary_10_1007_s00210_025_04081_3
crossref_primary_10_32604_or_2024_048778
crossref_primary_10_1134_S1068162024050182
crossref_primary_10_3390_ijms24054864
crossref_primary_10_1016_j_gene_2024_148904
crossref_primary_10_1007_s12033_024_01161_2
crossref_primary_10_1002_pro_4867
crossref_primary_10_1016_j_adcanc_2024_100130
crossref_primary_10_3390_ijms25126314
crossref_primary_10_1016_j_biopha_2025_117943
crossref_primary_10_1016_j_bbrc_2024_149884
crossref_primary_10_3390_app15168772
crossref_primary_10_1016_j_bbcan_2024_189250
crossref_primary_10_1016_j_ipha_2024_01_013
crossref_primary_10_1186_s12951_022_01553_z
crossref_primary_10_1016_j_jics_2025_102112
crossref_primary_10_3389_fphar_2024_1437071
crossref_primary_10_1002_ardp_202300640
crossref_primary_10_3390_cimb46040222
crossref_primary_10_1002_ardp_202400873
crossref_primary_10_1186_s12885_024_13366_4
crossref_primary_10_1016_j_crbiot_2025_100330
crossref_primary_10_1016_j_phymed_2024_155858
crossref_primary_10_1080_17568919_2024_2351291
crossref_primary_10_1002_jbt_23732
crossref_primary_10_1016_j_jhip_2025_05_001
crossref_primary_10_2147_OTT_S425523
crossref_primary_10_1177_20503121251328486
crossref_primary_10_3390_cancers15245857
crossref_primary_10_1016_j_jep_2024_118261
crossref_primary_10_1007_s10555_024_10188_5
crossref_primary_10_1038_s41598_024_75332_1
crossref_primary_10_1016_j_ijbiomac_2025_145514
crossref_primary_10_1186_s12885_024_12528_8
crossref_primary_10_1016_j_fitote_2024_106125
crossref_primary_10_3390_ph18060895
crossref_primary_10_1016_j_prp_2023_154851
crossref_primary_10_1186_s12964_023_01106_3
crossref_primary_10_3389_fonc_2025_1494723
crossref_primary_10_3390_ijms26125672
crossref_primary_10_1016_j_prp_2023_154735
crossref_primary_10_1007_s11596_023_2777_7
crossref_primary_10_1111_php_13957
crossref_primary_10_3390_jcm14061989
crossref_primary_10_1002_ddr_22133
crossref_primary_10_3390_ijms25137292
crossref_primary_10_1002_slct_202502455
crossref_primary_10_1016_j_rechem_2025_102715
crossref_primary_10_1038_s41598_025_11532_7
crossref_primary_10_1016_j_ctarc_2025_100918
crossref_primary_10_1021_acsptsci_5c00312
crossref_primary_10_1007_s12032_024_02598_w
crossref_primary_10_3390_ph18040494
crossref_primary_10_1021_acsabm_5c00616
crossref_primary_10_1038_s41598_024_72532_7
crossref_primary_10_1038_s41598_023_39409_7
crossref_primary_10_31083_j_fbl2907239
crossref_primary_10_1007_s12033_024_01361_w
crossref_primary_10_1080_01635581_2025_2521884
crossref_primary_10_3390_pharmaceutics15051406
crossref_primary_10_2217_nnm_2023_0202
crossref_primary_10_7717_peerj_15099
crossref_primary_10_1002_iub_2914
crossref_primary_10_1016_j_lfs_2023_121535
crossref_primary_10_1002_cnr2_70012
crossref_primary_10_3390_cancers15133448
crossref_primary_10_1007_s12032_025_02812_3
crossref_primary_10_3390_cancers16091657
crossref_primary_10_3390_biom12111565
crossref_primary_10_3390_cells13060510
crossref_primary_10_3390_vaccines10101727
crossref_primary_10_3390_ijms25021093
crossref_primary_10_3390_ijms26157468
crossref_primary_10_3389_fphar_2024_1348076
crossref_primary_10_1016_j_bcp_2025_116923
crossref_primary_10_1016_j_bmc_2023_117442
crossref_primary_10_1016_j_pmatsci_2025_101528
crossref_primary_10_3389_fonc_2023_1170264
crossref_primary_10_3389_fmed_2025_1548603
crossref_primary_10_1002_jhet_4675
crossref_primary_10_1016_j_cpt_2024_11_002
crossref_primary_10_3390_microbiolres14020037
crossref_primary_10_1016_j_bios_2023_115985
crossref_primary_10_1080_15583724_2024_2427184
crossref_primary_10_3390_cancers16132479
crossref_primary_10_1016_j_genrep_2024_101990
crossref_primary_10_1080_03639045_2025_2563633
crossref_primary_10_2147_IJN_S500997
crossref_primary_10_1016_j_jphotobiol_2025_113229
crossref_primary_10_1080_17568919_2025_2485867
crossref_primary_10_1016_j_crphar_2024_100204
crossref_primary_10_1080_15384101_2025_2543091
crossref_primary_10_1007_s12032_025_02740_2
crossref_primary_10_1002_jbt_70394
crossref_primary_10_3390_cancers15184448
crossref_primary_10_1080_07391102_2023_2247087
crossref_primary_10_3390_diagnostics13243617
crossref_primary_10_1097_JS9_0000000000001803
crossref_primary_10_1002_jbt_70397
crossref_primary_10_1134_S1070363224030198
Cites_doi 10.1016/j.tiv.2010.12.010
10.2147/PGPM.S86672
10.1371/journal.pone.0150499
10.3390/molecules191015584
10.1111/J.1349-7006.2007.00538.X
10.1006/bbrc.2001.5262
10.4161/epi.28601
10.1038/s41563-018-0028-2
10.1186/s12931-015-0285-4
10.1186/s12943-017-0743-3
10.1038/nrc706
10.1002/jcp.29019
10.1186/s12885-016-2790-3
10.1155/2014/135916
10.1038/bjc.1997.238
10.1002/ijc.24135
10.1126/science.293.5536.1793
10.4161/auto.5.8.9996
10.1126/science.3798106
10.1074/jbc.M205477200
10.1038/nrclinonc.2015.146
10.2174/1381612822666160617112111
10.15430/JCP.2020.25.3.127
10.1007/s10238-013-0250-9
10.1016/j.phrs.2013.07.009
10.1186/s13148-018-0587-8
10.1016/j.jconrel.2012.05.051
10.1038/onc.2015.98
10.3945/an.110.1004
10.1016/j.thromres.2010.01.036
10.1016/S0092-8674(01)00518-9
10.4149/neo_2018_180921N708
10.1002/stem.154
10.3332/ecancer.2019.961
10.1038/319230a0
10.1038/srep12291
10.1016/j.coi.2015.10.009
10.1007/BF00182138
10.1016/j.actbio.2017.04.029
10.1016/S0140-6736(06)68439-0
10.2147/IJN.S27864
10.1038/nrm2646
10.1001/jamaoncol.2018.3267
10.1158/1078-0432.CCR-05-2763
10.18632/oncotarget.2469
10.1016/j.ccr.2014.05.019
10.1002/ijc.23501
10.1016/j.ccr.2009.03.018
10.1038/leu.2009.76
10.1002/ijc.2910540421
10.1042/BST20180269
10.1158/2159-8290.CD-13-0424
10.1158/1535-7163.1119.3.9
10.18632/oncotarget.742
10.1208/s12248-017-0057-9
10.1182/blood-2005-08-3351
10.1073/pnas.84.24.9261
10.1038/nature13166
10.1002/cncr.26734
10.1016/j.canlet.2014.03.013
10.1038/sj.onc.1203078
10.1038/leu.2010.55
10.2174/157488551001150825100450
10.1001/jamaoncol.2015.2286
10.1046/j.1365-2125.2002.01591.x
10.1158/0008-5472.CAN-12-3308
10.1203/01.pdr.0000203093.10908.bb
10.1016/j.ctrv.2011.06.005
10.1158/1078-0432.CCR-18-0856
10.1371/journal.pone.0050999
10.18632/oncotarget.22494
10.1111/J.1742-4658.2012.08589.X
10.1126/science.1241328
10.1002/ijc.30543
10.1002/wsbm.1408
10.1016/j.addr.2013.09.019
10.1016/j.nano.2011.06.005
10.1038/s41374-018-0027-6
10.2174/156800906777441753
10.1093/jmcb/mjy072
10.2217/nnm.12.176
10.1021/acschembio.7b00147
10.1158/0008-5472.596.65.2
10.1038/nri1150
10.1158/1078-0432.CCR-16-1040
10.1016/j.colsurfb.2010.01.033
10.3390/vetsci2030150
10.1016/j.coi.2016.01.002
10.1126/science.1242454
10.1016/S0065-2776(04)82006-6
10.1038/tpj.2016.17
10.18632/oncotarget.25197
10.1016/j.canlet.2014.06.008
10.1158/2326-6066.CIR-16-0297
10.18632/oncotarget.13475
10.1172/JCI84427
10.1074/jbc.M110.125906
10.1038/cgt.2008.4
10.3390/ijms13089545
10.3892/ijo.7.3.461
10.1002/cbin.10995
10.1186/s12943-019-1016-0
10.1038/emboj.2013.97
10.1093/hmg/ddh008
10.1182/blood-2011-07-370775
10.1038/sj.onc.1206940
10.1158/1940-6207.CAPR-09-0194
10.1016/j.ejphar.2013.09.044
10.3389/FPHAR.2013.00028
10.1158/1940-6207.CAPR-12-0275
10.18632/oncotarget.11256
10.1089/scd.2011.0709
10.1016/j.jconrel.2017.03.022
10.1242/dmm.000976
10.1016/j.mattod.2018.12.003
10.1038/cr.2016.53
10.1371/journal.pone.0012038
10.1016/j.drup.2011.03.001
10.1038/nature10738
10.1038/nrc3038
10.1126/scitranslmed.aat5690
10.1021/jm401330r
10.1016/j.biomaterials.2012.08.007
10.1016/j.lfs.2018.06.034
10.1038/NATURE12624
10.1016/S0928-0987(03)00204-5
10.4081/dts.2012.e10
10.1002/JCB.23356
10.1016/j.apsb.2016.09.002
10.1038/onc.2016.521
10.1016/0092-8674(94)90212-7
10.1038/bjc.2013.826
10.1038/onc.2011.611
10.1038/nm0898-915
10.1038/bjc.2014.116
10.1007/s40139-013-0036-5
10.1016/j.bbrc.2018.11.061
10.1016/0005-2736(76)90160-7
10.1016/j.ccell.2015.03.008
10.1073/pnas.86.9.3179
10.1177/107602960401000207
10.1056/nejmoa1215530
10.1101/cshperspect.a008722
10.1371/journal.pone.0074924
10.20517/CDR.2019.10
10.1517/17425255.2.3.351
10.1016/j.jconrel.2017.09.042
10.1016/j.jconrel.2012.03.020
10.1245/s10434-013-3119-y
10.3389/fonc.2020.01495
10.1016/j.toxlet.2020.04.005
10.1038/onc.2012.179
10.1016/j.patbio.2009.11.002
10.3892/ijo.2018.4412
10.1002/cbin.11494
10.1080/2162402X.2017.1388484
10.1002/adma.201403562
10.1146/annurev.bi.58.070189.001033
10.1038/sj.bjp.0703920
10.1007/978-3-540-69297-3_10
10.1593/neo.05250
10.1200/JCO.1992.10.7.1049
10.1101/gr.184901
10.1039/C6QM00289G
10.3390/ijms19123950
10.1093/jnci/djt347
10.4049/jimmunol.1701019
10.1016/J.BLRE.2005.08.003
10.1158/1535-7163.MCT-16-0728
10.1016/j.ijpharm.2013.05.015
10.1038/srep31009
10.1023/A:1006500406240
10.1016/S0952-7915(96)80079-3
10.1097/00001813-199801000-00006
10.1053/j.gastro.2016.05.048
10.1038/sj.bjc.6606071
10.11606/issn.2358-792x.v17i2p111-116
10.3389/fmicb.2019.02690
10.1159/000190289
10.1158/1535-7163.MCT-16-0740
10.1158/0008-5472.CAN-06-1648
10.2217/nnm.13.182
10.1155/2014/794756
10.1371/journal.pone.0022429
10.1016/j.celrep.2018.04.046
10.1016/s0169-5002(96)90215-9
10.1016/j.drup.2012.03.003
10.1016/j.ccr.2006.06.001
10.3390/cancers10120471
10.1016/j.gene.2016.10.015
10.1016/S0140-6736(04)17398-4
10.1021/mp500257s
10.1155/2014/541340
10.7150/ijms.5011
10.7314/APJCP.2013.14.12.7421
10.1242/jcs.078030
10.1016/0092-8674(86)90595-7
10.1016/j.vaccine.2019.05.024
10.1177/1010428317695525
10.1158/1078-0432.CCR-09-0737
10.3322/caac.21590
10.1038/srep22847
10.1007/s13277-014-2377-z
10.3389/FMOLB.2020.00193/BIBTEX
10.1248/bpb.b16-00684
10.1002/cbf.3276
10.1074/jbc.M011294200
10.1182/blood.V76.12.2510.2510
10.1073/pnas.1510837112
10.1200/JCO.2005.01.6196
10.1158/0008-5472.CAN-15-0391
10.1166/jbn.2018.2540
10.1038/nature14136
10.1016/J.CELL.2011.07.026
10.3389/fphar.2019.01614
10.1155/2019/5613417
10.1002/jso.24614
10.1371/journal.pone.0036116
10.1016/S0140-6736(09)61248-4
10.1016/j.biomaterials.2016.08.001
10.1016/j.yexcr.2017.03.008
10.15171/apb.2017.041
10.1002/ijc.20570
10.1186/s13048-018-0418-8
10.1016/j.febslet.2013.06.058
10.1158/0008-5472.CAN-17-1904
10.1182/blood.V26.5.642.642
10.1016/j.celrep.2013.06.026
10.1093/jnci/81.16.1235
10.1177/107327480901600204
10.1038/nature11183
10.1016/j.gene.2015.01.010
10.1053/j.seminoncol.2015.11.001
10.1007/s00262-009-0719-2
10.1016/j.biopha.2012.12.002
10.3892/ijo.2018.4609
10.18632/oncotarget.12461
10.1021/mp100012s
10.22038/IJBMS.2017.25145.6230
10.1158/1535-7163.MCT-08-1090
10.1038/s41598-020-59939-8
10.1056/NEJMra072367
10.1136/gutjnl-2013-306271
10.4137/CCREP.S3078
10.1038/sj.cgt.7700196
10.1002/1878-0261.12155
10.1016/j.jphotobiol.2017.07.003
10.1016/0925-4439(94)90063-9
10.1038/sj.bjc.6604971
10.1158/1078-0432.CCR-16-1924
10.1016/j.biomaterials.2011.08.041
10.1186/s13046-020-01641-8
10.1089/dna.2010.1143
10.1016/J.CELL.2013.11.012
10.1517/14796694.1.1.57
10.1002/mc.22405
10.1016/j.biomaterials.2017.08.030
10.1016/j.cell.2010.02.027
10.1016/j.oraloncology.2019.02.027
10.2147/CMAR.S34859
10.1038/onc.2009.422
10.1016/S1470-2045(11)70286-8
10.1016/J.TIG.2015.11.003
10.1126/scitranslmed.3007974
10.1371/journal.pmed.0020245
10.1038/onc.2016.206
10.1002/ijc.10208
10.1158/1535-7163.MCT-15-1018
10.1016/j.mehy.2005.07.023
10.1016/j.biomaterials.2020.120537
10.1002/1097-0142(19940501)73:9<2359::aid-cncr2820730919>3.0.co;2-9
10.1021/nn2033105
10.1038/onc.2013.297
10.1016/j.addr.2012.03.008
10.1007/s10565-020-09553-1
10.1016/j.biopha.2017.10.146
10.2147/IJN.S131516
10.1038/nrc2499
10.1016/j.ejphar.2014.05.026
10.1158/2159-8290.CD-12-0012
10.1073/pnas.0408592102
10.1016/j.canlet.2016.03.029
10.1016/j.cellsig.2013.08.032
10.1016/j.ccell.2016.04.014
10.1007/s00775-012-0960-6
10.1016/j.canlet.2013.06.016
10.1021/acsnano.8b01573
10.1016/j.ccr.2012.03.003
10.1073/pnas.0706867105
10.3390/ijms21051618
10.1007/BF01191800
10.1016/j.ymthe.2019.05.017
10.1016/S0959-8049(97)00075-0
10.18632/oncotarget.4814
10.1038/s41568-018-0037-0
10.5176/2345-7201_1.4.32
10.1007/s002620050519
10.1186/s13059-020-1940-8
10.1038/s41598-017-09375-y
10.1021/cn100078a
10.1038/nrc2892
10.1038/srep31740
10.3390/IJMS10093776
10.1038/nmeth.3433
10.1038/nrdp.2016.22
10.1073/pnas.84.9.3004
10.1158/0008-5472.CAN-14-2156
10.4172/2157-7439.1000265
10.1016/j.chembiol.2013.04.007
10.1016/J.BBRC.2013.04.010
10.2174/138945011798184146
10.3109/10409239509083491
10.1590/1414-431x20176472
10.1016/j.biomaterials.2013.01.055
10.1038/s41419-020-03150-0
10.1007/s11302-013-9372-5
10.1038/ncomms2282
10.1002/ijc.30752
10.3389/FCHEM.2018.00360
10.1093/jnci/djv135
10.1159/000495714
10.1158/0008-5472.CAN-04-1800
10.1038/bjc.1991.152
10.1158/1541-7786.MCR-05-0007
10.1093/jnci/88.18.1269
10.1124/dmd.107.014902
10.1002/path.1706
10.1158/0008-5472.CAN-11-1674
10.1038/sj.jhh.1001863
10.1002/btm2.10131
10.1038/nrc3950
10.3892/mco.2017.1247
10.3389/fonc.2019.00080
10.1126/science.1232033
10.1128/MCB.00090-14
10.1016/j.jprot.2013.02.021
10.1126/scisignal.2004652
10.1038/sj.jhh.1002100
10.2174/09298673113209990226
10.3390/pharmaceutics12020185
10.1016/j.drup.2019.100647
10.1038/89937
10.1038/tpj.2015.98
10.1126/science.1360704
10.1128/mcb.9.10.4357
10.7554/eLife.18970
10.1097/00001813-199102000-00002
10.3389/fphys.2014.00091
10.26355/eurrev_201903_17391
10.1111/ijlh.12928
10.1158/1535-7163.MCT-07-0148
10.1080/15476286.2020.1737787
10.1016/j.drup.2011.04.002
10.1158/1078-0432.CCR-11-2776
10.3978/j.issn.2218-6751.2013.12.05
10.1038/bjc.2013.188
10.3892/etm.2017.5354
10.1074/jbc.274.51.36321
10.1016/j.ccr.2004.06.026
10.1007/s13402-017-0354-4
10.18632/oncotarget.21231
10.1038/nrc3262
10.1111/j.1349-7006.2006.00300.x
10.1158/1078-0432.CCR-07-4525
10.1038/nm.2609
10.1016/j.phrs.2009.11.010
10.2174/1568009615666150225121508
10.1155/2015/635745
10.1200/JCO.19.01740
10.1038/bjc.1996.313
10.1371/journal.pone.0082650
10.1038/s41419-019-1371-1
10.1085/JGP.201411164
10.4161/sgtp.20755
10.1038/cddis.2017.53
10.1186/s12935-019-0771-8
10.4161/cbt.7.12.7069
10.1016/J.BBCAN.2016.03.005
10.1016/j.vaccine.2013.10.003
10.3892/or.2018.6762
10.1007/978-94-017-2374-9_19
10.1158/0008-5472.CAN-11-1792
10.1186/s13046-018-0845-9
10.1038/s43018-020-0037-3
10.1186/s12935-019-0951-6
10.3892/ijo.2018.4614
10.1055/s-0029-1242458
10.1007/s10495-019-01526-y
10.1038/srep20502
10.3892/ijo.2018.4467
10.1371/journal.pone.0055096
10.1038/leu.2014.159
10.1158/1940-6207.CAPR-14-0213
10.3389/fphar.2014.00159
10.1371/journal.pone.0061515
10.1038/nature12626
10.1111/j.1365-2141.2011.08752.x
10.1172/JCI28656
10.1074/jbc.M109.028068
10.3892/ijo.2018.4376
10.1126/scitranslmed.aam7049
10.15698/cst2019.08.195
10.1002/mc.23109
10.1002/(SICI)1097-0215(19990219)84:1<6::AID-IJC2>3.0.CO;2-T
10.1146/annurev.med.53.082901.103929
10.1186/1479-5876-6-24
10.1016/S0889-8588(18)30104-7
10.1146/annurev.biochem.71.102301.093055
10.3390/cancers6031769
10.3389/fonc.2014.00220
10.18632/oncotarget.6113
10.1038/s41392-021-00572-w
10.3892/ol.2017.5727
10.1021/nn200007z
10.1016/j.emc.2013.09.002
10.1369/0022155412452567
10.1016/j.prp.2018.12.033
10.1158/0008-5472.CAN-13-1541
10.3390/cells8070674
10.1002/1097-0142(19901015)60:8+<2075::AID-CNCR2820601521>3.0.CO;2-F
10.3390/cancers9060062
10.1158/1940-6207.CAPR-17-0108
10.1158/1078-0432.CCR-11-3313
10.1097/MPA.0000000000001052
10.1016/j.stemcr.2019.05.005
10.18632/oncotarget.11044
10.1093/carcin/bgn231
10.1182/blood-2016-01-692244
10.1177/1533033819828709
10.1073/pnas.95.26.15665
10.1001/jama.1946.02870380008004
10.1021/mp400547u
10.1016/j.ejpb.2012.12.009
10.12688/f1000research.10691.1
10.1016/j.celrep.2017.05.014
10.1016/J.CELL.2011.10.026
ContentType Journal Article
Copyright Copyright © 2022 Emran, Shahriar, Mahmud, Rahman, Abir, Siddiquee, Ahmed, Rahman, Nainu, Wahyudin, Mitra, Dhama, Habiballah, Haque, Islam and Hassan.
Copyright © 2022 Emran, Shahriar, Mahmud, Rahman, Abir, Siddiquee, Ahmed, Rahman, Nainu, Wahyudin, Mitra, Dhama, Habiballah, Haque, Islam and Hassan 2022 Emran, Shahriar, Mahmud, Rahman, Abir, Siddiquee, Ahmed, Rahman, Nainu, Wahyudin, Mitra, Dhama, Habiballah, Haque, Islam and Hassan
Copyright_xml – notice: Copyright © 2022 Emran, Shahriar, Mahmud, Rahman, Abir, Siddiquee, Ahmed, Rahman, Nainu, Wahyudin, Mitra, Dhama, Habiballah, Haque, Islam and Hassan.
– notice: Copyright © 2022 Emran, Shahriar, Mahmud, Rahman, Abir, Siddiquee, Ahmed, Rahman, Nainu, Wahyudin, Mitra, Dhama, Habiballah, Haque, Islam and Hassan 2022 Emran, Shahriar, Mahmud, Rahman, Abir, Siddiquee, Ahmed, Rahman, Nainu, Wahyudin, Mitra, Dhama, Habiballah, Haque, Islam and Hassan
DBID AAYXX
CITATION
7X8
5PM
DOA
DOI 10.3389/fonc.2022.891652
DatabaseName CrossRef
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE - Academic
DatabaseTitleList
MEDLINE - Academic
CrossRef
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: 7X8
  name: MEDLINE - Academic
  url: https://search.proquest.com/medline
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2234-943X
ExternalDocumentID oai_doaj_org_article_f892769914c74af7be4f6c343383b46a
PMC9262248
10_3389_fonc_2022_891652
GroupedDBID 53G
5VS
9T4
AAFWJ
AAKDD
AAYXX
ACGFO
ACGFS
ADBBV
ADRAZ
AFPKN
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
BCNDV
CITATION
DIK
EBS
EJD
EMOBN
GROUPED_DOAJ
GX1
HYE
KQ8
M48
M~E
OK1
PGMZT
RNS
RPM
7X8
5PM
ID FETCH-LOGICAL-c439t-b5ca224aa8f3d3e7c1f32e2ba631444d11c4492909816e73d10a68e35a69cfe53
IEDL.DBID DOA
ISICitedReferencesCount 383
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000827820300001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 2234-943X
IngestDate Fri Oct 03 12:23:48 EDT 2025
Thu Aug 21 18:29:06 EDT 2025
Thu Sep 04 20:07:44 EDT 2025
Sat Nov 29 01:50:24 EST 2025
Tue Nov 18 22:26:20 EST 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Language English
License This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c439t-b5ca224aa8f3d3e7c1f32e2ba631444d11c4492909816e73d10a68e35a69cfe53
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
This article was submitted to Pharmacology of Anti-Cancer Drugs, a section of the journal Frontiers in Oncology
Reviewed by: Hodaka Fujii, Hirosaki University, Japan; Ki Hyun Nam, Pohang University of Science and Technology, South Korea; Ana Podolski-Renic, Institute for Biological Research “Siniša Stanković” – National Institute of Republic of Serbia, Serbia
Edited by: Milica Pešić, University of Belgrade, Serbia
OpenAccessLink https://doaj.org/article/f892769914c74af7be4f6c343383b46a
PMID 35814435
PQID 2688087162
PQPubID 23479
ParticipantIDs doaj_primary_oai_doaj_org_article_f892769914c74af7be4f6c343383b46a
pubmedcentral_primary_oai_pubmedcentral_nih_gov_9262248
proquest_miscellaneous_2688087162
crossref_primary_10_3389_fonc_2022_891652
crossref_citationtrail_10_3389_fonc_2022_891652
PublicationCentury 2000
PublicationDate 2022-06-23
PublicationDateYYYYMMDD 2022-06-23
PublicationDate_xml – month: 06
  year: 2022
  text: 2022-06-23
  day: 23
PublicationDecade 2020
PublicationTitle Frontiers in oncology
PublicationYear 2022
Publisher Frontiers Media S.A
Publisher_xml – name: Frontiers Media S.A
References Austin Doyle (B79) 1998; 95
An (B122) 2017; 7
Zhao (B272) 2009; 284
Bae (B349) 2015; 29
Kapse-Mistry (B28) 2014; 5
Wang (B54) 2017; 8
ErzaMclendzZhong (B19) 2021; 6
YiRen (B225) 2017; 16
Ren (B471) 2018; 11
Garcia (B355) 2014; 34
Warfel (B179) 2016; 15
Yeldag (B34) 2018; 10
Jones (B136) 2016; 1865
Mizushima (B199) 2011; 147
Barazas (B468) 2018; 23
Fu (B15) 2019; 19
Magee (B291) 2012; 21
Posuwan (B324) 2016; 11
Ding (B296) 2015; 559
Wan (B454) 2019; 26
Qin (B315) 2017; 12
Freyssinet (B370) 2010; 125
Daniilidis (B472) 2007; 11
Visvader (B290) 2008; 8
Antonyak (B383) 2012; 3
Skrypek (B293) 2013; 32
Lonial (B363) 2020; 38
Zhou (B452) 2014; 509
Gebremeskel (B197) 2015; 6
Zandvliet (B69) 2015; 2
Vicente-duen (B145) 2013; 32
Kannan (B250) 2011; 2
Sato (B297) 2018; 47
Tsuruma (B396) 2008; 6
Tang (B394) 2012; 3
Aluigi (B139) 1995; 7
Haber (B262) 2006; 24
Sun (B465) 2018; 98
Wang (B41) 2019; 2
Harper (B327) 2004; 364
Steele (B360) 2016; 29
Ghasemi (B117) 2017; 24
Hilgendorf (B260) 2007; 35
Gu (B210) 2017; 8
Joshi (B445) 2014; 9
Shouzu (B387) 2004; 10
Mo (B103) 2012; 3
Stanton (B343) 2019; 37
Vysotski (B390) 2014; 1
Croce (B380) 1999; 274
Moitra (B123) 2015; 2015
Ebben (B347) 2016; 55
Di Virgilio (B66) 2017; 36
Park (B289) 2014; 2
Roeser (B319) 2015; 34
Pugh (B162) 2017; 356
Sigismund (B109) 2018; 12
Choi (B118) 2010; 1
Mosaffa (B140) 2011; 30
van de Ven (B448) 2017; 16
Qian (B56) 2014; 351
Hua (B206) 2018; 42
Greenhalf (B294) 2014; 106
Ugurel (B279) 2006; 12
Kulkarni (B382) 2010; 29
Wassmer (B388) 2005; 2
Finn (B351) 2003; 3
Highfill (B359) 2014; 6
Niederst (B84) 2013; 6
Quintás-Cardama (B50) 2009; 16
Borst (B256) 2002; 71
Drescher (B247) 2002; 53
Xue (B125) 2012; 113
Gu (B418) 2012; 8
Du (B277) 2005; 113
Sadok (B386) 2015; 75
Reis (B61) 2019; 47
Kang (B274) 2013; 339
Qu (B108) 2013; 8
Nooka (B350) 2018; 4
Glasspool (B93) 2014; 110
Wang (B221) 2019; 19
Lee (B227) 2012; 9
Barenholz (B406) 2012; 160
Montero (B433) 2020; 12
Shang (B132) 2014; 33
Kopera (B342) 2014; 2014
Shechner (B461) 2015; 12
Manolitsas (B65) 1997; 75
Yakisich (B288) 2012; 2
Kurz (B96) 2001; 285
Harper (B328) 2006; 367
Hu (B302) 2019; 58
Ueno (B295) 2009; 100
Lau (B463) 2020; 21
Li (B419) 2018; 17
Kyung (B74) 2009; 10
Chang (B192) 1999; 18
Wu (B229) 2014; 347
Sayin (B450) 2017; 387
Wang (B40) 2015
Zhang (B209) 2019; 23
Li (B249) 2012; 22
Lollini (B320) 2005; 1
Lu (B280) 2015; 10
Zhang (B306) 2014; 738
Arora (B36) 2013; 155
Han (B4) 2020; 10
Gusterson (B149) 1992; 10
Willis (B340) 2020; 26
Gatenby (B47) 2010; 10
Dean (B97) 2001; 42
Norouzi-Barough (B29) 2018; 21
Cheng (B128) 2012; 279
Du (B215) 2018; 15
Zhou (B59) 2012; 72
Kawamura (B286) 1997; 33
di Virgilio (B53) 2018; 18
Zhao (B31) 2017; 6
Wu (B188) 2015; 5
Roseblade (B27) 2015; 15
Braun (B379) 1999; 84
Engelman (B83) 2006; 116
Wang (B362) 2017; 10
Liang (B13) 1996; 29
Rees (B60) 2009; 10
Sharma (B90) 2010; 141
Rice (B167) 1987; 84
Park (B273) 2008; 7
Beatty (B334) 2010; 3
Satapathy (B425) 2013; 8
Katayama (B266) 2007; 6
Furukawa (B276) 1995; 1
Hientz (B110) 2017; 8
Du (B404) 2018; 12
Tanio (B154) 1992; 30
Malek (B114) 2014; 5
Gong (B373) 2013; 721
Zhang (B183) 2013; 587
Mansoori (B18) 2017; 7
Keppler (B252) 2011
Lukowski (B427) 2018; 14
Frei (B135) 1965; 26
Jia (B424) 2020; 21
Erdal (B270) 2005; 102
Ding (B49) 2012; 481
Rohwer (B178) 2010; 5
Straussman (B88) 2012; 487
James (B238) 2012; 7
Schinkel (B10) 1991; 51
Hu (B75) 2016; 32
Kleeff (B470) 2016; 2
Sauna (B255) 2001; 276
Baghbani-Arani (B421) 2017; 173
Terai (B458) 2018; 78
Ohata (B112) 2017
Zhang (B308) 2017; 51
Bebawy (B303) 2009; 23
Levingston (B338) 2017; 140
Krall (B464) 2017; 6
Slamon (B148) 1979
Gong (B211) 2017; 266
Gottesman (B258) 2002; 2
Sindac (B246) 2013; 56
Cai (B208) 2019; 18
Ku (B80) 2001; 132
Chen (B5) 2019; 215
Lok (B466) 2017; 23
Xia (B131) 2008; 123
Graves (B375) 2004; 64
Guo (B189) 2016; 16
Varela-Moreira (B434) 2017; 1
Pan (B444) 2016; 7
Sullivan (B172) 2009; 8
Bartkova (B156) 1995; 55
Lim (B435) 2012; 64
Liu (B443) 2010; 7
Degenhardt (B202) 2006; 10
Umar (B25) 2014; 7
Ho (B124) 2006; 6
Martín (B127) 2013; 108
Ernest (B9) 1997; 77
Chang (B321) 2016; 151
Al-Anazi (B73) 2009; 2
Sharma (B332) 2012; 118
Teixeira (B159) 1995; 55
Shen (B428) 2012; 33
Chang (B190) 1999; 59
Tian (B446) 2014; 26
Jing (B214) 2020; 36
Allen (B245) 2000; 60
Jedlitschky (B98) 2006; 2
Masumoto (B151) 1997; 24
Merino (B467) 2017; 9
Nadanaciva (B271) 2011; 25
Dolo (B376) 1999; 17
Benner (B37) 1991; 2
Lal (B102) 2017; 17
Shao (B300) 2019; 18
Zins (B384) 2013; 8
Peng (B429) 2016; 106
Mali (B451) 1979
Nooter (B244) 1991; 63
Dong (B314) 2018; 53
Lee (B100) 2006; 59
Yamazaki (B152) 1994; 1226
Kimura (B337) 2013; 6
Richmond (B242) 2008; 1
Levingston (B339) 2017; 9
Isaac (B180) 2011; 14
Taipalensuu (B248) 2004; 21
Forni (B364) 2000; 60
Abe (B356) 2010; 59
ter Beek (B62) 2014; 143
Galski (B243) 1989; 9
Kalra (B12) 1993; 54
Gao (B403) 2012; 162
Zhang (B438) 2017; 58
Liu (B182) 2020; 39
Nomura (B392) 2005; 19
Lu (B372) 2013; 76
Xiong (B223) 2017; 36
Yanase (B263) 2004; 3
Lu (B282) 2006; 66
Karban (B240) 2004; 13
Tanwar (B477) 2014; 2014
Vasconcelos (B317) 2019; 47
Wright (B459) 2017; 12
Yarden (B147) 1989; 86
Nishihashi (B171) 2017; 40
Abolhoda (B261) 1999; 5
Croce (B144) 2008; 358
Stein (B141) 1998
Xie (B205) 2013; 8
B16
Wei (B398) 2020; 45
Chang (B322) 2009; 181
Zahiri (B437) 2020; 235
Yao (B402) 2020; 7
Chen (B181) 2005; 3
Kimura (B51) 1963; 17
Hochhauser (B155) 1996; 88
Huang (B414) 2016; 76
te Poele (B191) 2002; 62
Bosch (B369) 2016; 13
Salvestrini (B68) 2012; 119
Goodman (B2) 1946; 132
Fojo (B119) 1987; 60
Liu (B426) 2017; 7
Xu (B198) 2019; 27
Zeller (B91) 2012; 31
Corcoran (B307) 2012; 7
Kimura (B378) 1998; 4
Zhang (B165) 2020; 331
Paavonen (B330) 2009; 374
He (B220) 2015; 6
Curiel (B138) 2012; 15
Nabekura (B251) 2010; 61
Chen (B341) 2018; 7
Finn (B26) 2016; 39
Yamamoto (B146) 1986; 319
Kaelin (B161) 2017; 128
Yu (B143) 1998; 27
Fracol (B333) 2013; 20
Zhang (B207) 2018; 207
Puissant (B269) 2010; 24
Gasparri (B299) 2017; 39
Lee (B326) 2017; 6
Lu (B281) 2010; 1
Mutoh (B265) 2006; 97
Lobb (B309) 2017; 141
Bauer (B92) 2014; 110
Garraway (B230) 2012; 2
Bosch (B325) 2013; 31
Juliano (B77) 1976; 455
Huang (B43) 2016; 6
Fox (B381) 1990
Wilson (B168) 1989; 81
Walther (B137) 1994; 120
Li (B411) 2017; 19
Liu (B447) 2016; 6
Xue (B33) 2018
Schneider (B57) 2013; 18
Chang (B157) 1996; 7
Gopinath (B422) 2010; 77
Yasuhisa (B95) 2007; 98
Gong (B374) 2014; 4
Wang (B431) 2011; 32
Nomura (B391) 2007; 21
B105
Autry (B232) 2020; 1
B104
Gupta (B35) 2011; 146
Gottesman (B169) 2002; 2
Li (B234) 2019; 10
Lehtinen (B329) 2012; 13
Gottesman (B39) 2002; 53
Cufí (B213) 2012; 3
Haggar (B475) 2009; 22
Chen (B432) 2013; 452
O’Connor (B24) 2011; 154
Morioka (B283) 2001; 21
Zhou (B409) 2002; 62
Zhao (B200) 2019; 10
B236
B233
Ueda (B11) 1987; 84
Szakács (B259) 2004; 6
Moasser (B346) 2015; 1
Chen (B133) 2013; 25
Semenza (B160) 2001; 107
Reed (B158) 1995; 9
Calvert (B298) 2017; 19
Ma (B393) 2016; 26
Pedrini (B415) 2014; 11
Li (B440) 2012; 7
Ginestra (B377) 1998; 18
Ning (B305) 2017; 115
Wang (B439) 2014; 11
Yap (B385) 2012; 18
Ni (B323) 2010; 58
Huai (B420) 2019; 3
Li (B195) 2009; 15
Lee (B85) 2014; 26
Kang (B311) 2018; 37
Choudhari (B21) 2020; 10
Lee (B185) 2015; 16
Rohwer (B166) 2011; 14
Munn (B353) 2016; 39
Wang (B163) 2019; 11
Li (B407) 2013; 34
Chew (B469) 2018; 10
Liu (B176) 2009; 124
Disis (B366) 1996; 8
Goldman (B72) 2002; 8
Ahmad (B400) 2016; 22
Cole (B78) 1992; 258
Lesokhin (B358) 2012; 72
Macura (B399) 2012; 60
Koppenol (B58) 2011; 11
Li (B412) 2017; 145
Lu (B292) 2014
Jin (B6) 2020; 17
Ha (B455) 2016; 6
Ghasemi (B115) 2015; 32
Nathanson (B46) 1979
Jaiswal (B371) 2013; 8
Penet (B389) 2008; 105
Suh (B473) 2014; 14
Tětu (B150) 1994; 73
Cheung-Ong (B17) 2013; 20
Lohmueller (B336) 2016; 6
Webster (B436) 2013; 84
Pearce (B55) 2013; 342
Wang (B129) 2013; 434
Junttila (B48) 2013; 501
B267
Si (B476) 2019; 11
Schinkel (B257) 1994; 77
Lowenfeld (B331) 2017; 23
Livshits (B395) 2014; 32
Pucci (B20) 2019; 13
Chang (B254) 2001; 293
Gu (B318) 2020; 25
Lo (B416) 2013; 67
Gabrilovich (B352) 2017; 5
Gong (B120) 2012; 38
Gao (B441) 2011; 5
Ventola (B367) 2017; 42
Awad (B81) 2013; 368
Lei (B312) 2018; 40
Gewirtz (B194) 2002; 277
Hayes (B153) 1995; 30
Wang (B456) 2019; 9
Yang (B187) 2018; 53
Markman (B405) 2013; 65
Sampath (B32) 2006; 107
Tsai (B361) 2019; 91
Bruck (B239) 2013; 4
Gokhale (B408) 1996; 74
Nishibeppu (B301) 2020; 10
Burnstock (B67) 2013; 9
Huang (B222) 2019; 54
Shah (B410) 2017; 253
Montagut (B82) 2012; 18
Markouli (B237) 2019; 13
Fu (B442) 2021; 268
Wang (B184) 2020; 11
Xi (B224) 2019; 54
Vlad (B345) 2004; 82
Stromnes (B357) 2014; 63
Gao (B460) 2018; 41
Hou (B101) 2017; 8
Imai (B264) 2005; 65
Cao (B310) 2017; 35
Ostrand-Rosenberg (B354) 2018; 200
Chen (B7) 1986; 47
Piya (B212) 2016; 128
Zhou (B111) 2019; 11
Uramoto (B22) 2014; 3
Sánchez-Rivera (B462) 2015; 15
Rosa (B241) 2014; 21
Chen (B3) 2016; 595
Xiong (B217) 2017; 8
Endicott (B8) 1989; 58
Kreso (B45) 2012
Housman (B116) 2014; 6
Wirthner (B173) 2008; 29
Zahreddine (B30) 2013; 4
Chidambaran (B235) 2017; 17
Castells (B23) 2012; 13
Zhang (B130) 2013; 73
Chen (B134) 2013; 14
Schwarze (B193) 2005; 7
Meacham (B42) 2013; 501
Konermann (B453) 2015; 517
Cheever (B344) 2009; 15
Mensah (B449) 2019; 4
Hao (B177) 2008; 15
Lv (B304) 2014; 35
Longo-Sorbello (B76) 2001; 86
Marie Hardwick (B107) 2013; 5
Zhang (B316) 2018; 507
Lollini (B335) 2011; 12
Efferth (B278) 2008; 14
Wang (B474) 1996; 1
Challagundla (B52) 2015; 107
Song (B186) 2009; 5
Chen (B113) 2017; 8
Baguley (B121) 2010
Xiao (B457) 2018; 51
Amici (B365) 1998; 47
Jiang (B226) 2018; 97
Konieczkowski (B87) 2014; 4
Chang (B218) 2014; 2014
Tulsyan (B94) 2016; 9
Hirata (B89) 2015; 27
Al-Ali (B268) 2014
Takamura (B287) 2002; 98
Kurbacher (B285) 1998; 9
El-Deeb (B423) 2015; 6
Kurrey (B44) 2009; 27
Spreckelmeyer (B71) 2014; 19
Datta (B14) 2019; 24
Ozpolat (B201) 2015; 7
Chen (B413) 2010; 285
Wang (B417) 2011; 5
Sarvi (B126) 2014; 74
Li (B38) 2006; 20
García-Aranda (B106) 2018; 19
Lebedeva (B253) 2011; 6
Soares (B401) 2018; 6
Mai (B175) 2019; 66
Khandia (B204) 2019; 8
Siegel (B1) 2020; 70
Wojtowicz (B368) 2016; 48
Cumming (B64) 2001; 7
Sinha (B164) 2020; 12
Bae (B348) 2012; 18
Zhu (B170) 2005; 24
Longley (B231) 2005; 205
Sahoo (B70) 2014; 5
van Vlerken (B430) 2007; 67
Li (B275) 2013; 82
Ness (B284) 2002; 22
Bouquet (B174) 2011; 124
White (B203) 2012; 12
Zhang (B86) 2014; 9
Aqbi (B228) 2018; 9
Walther (B142) 2000; 7
Yamasaki (B99) 2011; 104
Chen (B219) 2017; 13
Zhang (B31
References_xml – volume: 25
  year: 2011
  ident: B271
  article-title: A High Content Screening Assay for Identifying Lysosomotropic Compounds
  publication-title: Toxicol Vitro
  doi: 10.1016/j.tiv.2010.12.010
– volume: 9
  year: 2016
  ident: B94
  article-title: The Effect of ABCB1 Polymorphisms on the Outcome of Breast Cancer Treatment
  publication-title: Pharmacogenomics Personalized Med
  doi: 10.2147/PGPM.S86672
– ident: B267
– volume: 11
  year: 2016
  ident: B324
  article-title: The Success of a Universal Hepatitis B Immunization Program as Part of Thailand’s EPI After 22 Years’ Implementation
  publication-title: PLos One
  doi: 10.1371/journal.pone.0150499
– volume: 19
  year: 2014
  ident: B71
  article-title: Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview Beyond Cisplatin
  publication-title: Molecules
  doi: 10.3390/molecules191015584
– volume: 98
  year: 2007
  ident: B95
  article-title: Mechanism of Multidrug Recognition by MDR1/ABCB1
  publication-title: Cancer Sci
  doi: 10.1111/J.1349-7006.2007.00538.X
– volume: 285
  year: 2001
  ident: B96
  article-title: Identification of DNA-Protein Interactions in the 5′ Flanking and 5′ Untranslated Regions of the Human Multidrug Resistance Protein (MRP1) Gene: Evaluation of a Putative Antioxidant Response Element/AP-1 Binding Site
  publication-title: Biochem Biophys Res Commun
  doi: 10.1006/bbrc.2001.5262
– volume: 9
  start-page: 37
  year: 2014
  ident: B86
  article-title: Integrated Analysis of DNA Methylation and mRNA Expression Profiling Reveals Candidate Genes Associated With Cisplatin Resistance in Non-Small Cell Lung Cancer
  publication-title: Epigenetics
  doi: 10.4161/epi.28601
– volume: 17
  year: 2018
  ident: B419
  article-title: A Facile Approach to Enhance Antigen Response for Personalized Cancer Vaccination
  publication-title: Nat Mater
  doi: 10.1038/s41563-018-0028-2
– volume: 16
  start-page: 1
  year: 2015
  ident: B185
  article-title: Autophagy Contributes to the Chemo-Resistance of Non-Small Cell Lung Cancer in Hypoxic Conditions
  publication-title: Respir Res
  doi: 10.1186/s12931-015-0285-4
– volume: 16
  start-page: 1
  year: 2017
  ident: B225
  article-title: Long Noncoding RNA MALAT1 Regulates Autophagy Associated Chemoresistance via miR-23b-3p Sequestration in Gastric Cancer
  publication-title: Mol Cancer
  doi: 10.1186/s12943-017-0743-3
– volume: 2
  start-page: 48
  year: 2002
  ident: B258
  article-title: Multidrug Resistance in Cancer: Role of ATP-Dependent Transporters
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc706
– volume: 235
  year: 2020
  ident: B437
  article-title: Hybrid Nanoreservoirs Based on Dextran-Capped Dendritic Mesoporous Silica Nanoparticles for CD133-Targeted Drug Delivery
  publication-title: J Cell Physiol
  doi: 10.1002/jcp.29019
– volume: 16
  start-page: 1
  year: 2016
  ident: B189
  article-title: Role of Autophagy and Lysosomal Drug Sequestration in Acquired Resistance to Doxorubicin in MCF-7 Cells
  publication-title: BMC Cancer
  doi: 10.1186/s12885-016-2790-3
– volume: 2014
  year: 2014
  ident: B342
  article-title: Visualization and Treatment of Subclinical Actinic Keratoses With Topical Imiquimod 5% Cream: An Observational Study
  publication-title: BioMed Res Int
  doi: 10.1155/2014/135916
– volume: 1
  year: 1995
  ident: B276
  article-title: Clinical Applications of the Histoculture Drug Response Assay
  publication-title: Clin Cancer Res
– volume: 75
  year: 1997
  ident: B65
  article-title: No Association of a 306-Bp Insertion Polymorphism in the Progesterone Receptor Gene With Ovarian and Breast Cancer
  publication-title: Br J Cancer
  doi: 10.1038/bjc.1997.238
– volume: 124
  year: 2009
  ident: B176
  article-title: Hypoxia-Mediated Up-Regulation of MGr1-Ag/37LRP in Gastric Cancers Occurs via Hypoxia-Inducible-Factor 1-Dependent Mechanism and Contributes to Drug Resistance
  publication-title: Int J Cancer
  doi: 10.1002/ijc.24135
– volume: 293
  year: 2001
  ident: B254
  article-title: Structure of MsbA From E. Coli: A Homolog of the Multidrug Resistance ATP Binding Cassette (ABC) Transporters
  publication-title: Science
  doi: 10.1126/science.293.5536.1793
– volume: 5
  year: 2009
  ident: B186
  article-title: Hypoxia-Induced Autophagy Contributes to the Chemoresistance of Hepatocellular Carcinoma Cells
  publication-title: Autophagy
  doi: 10.4161/auto.5.8.9996
– year: 1979
  ident: B148
  article-title: Human Breast Cancer: Correlation of Relapse and Survival With Amplification of the HER-2/Neu Oncogene
  publication-title: Science
  doi: 10.1126/science.3798106
– volume: 277
  year: 2002
  ident: B194
  article-title: Adriamycin-Induced Senescence in Breast Tumor Cells Involves Functional P53 and Telomere Dysfunction
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M205477200
– volume: 13
  year: 2016
  ident: B369
  article-title: HPV-FASTER: Broadening the Scope for Prevention of HPV-Related Cancer
  publication-title: Nat Rev Clin Oncol
  doi: 10.1038/nrclinonc.2015.146
– volume: 22
  start-page: 4360
  year: 2016
  ident: B400
  article-title: Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective
  publication-title: Curr Pharm Des
  doi: 10.2174/1381612822666160617112111
– volume: 25
  year: 2020
  ident: B318
  article-title: An Overview of Cancer Prevention: Chemoprevention and Immunoprevention
  publication-title: J Cancer Prev
  doi: 10.15430/JCP.2020.25.3.127
– volume: 14
  year: 2014
  ident: B473
  article-title: Association of Overexpression of Hexokinase II With Chemoresistance in Epithelial Ovarian Cancer
  publication-title: Clin Exp Med
  doi: 10.1007/s10238-013-0250-9
– volume: 76
  start-page: 77
  year: 2013
  ident: B372
  article-title: Microparticles Mediate MRP1 Intercellular Transfer and the Re-Templating of Intrinsic Resistance Pathways
  publication-title: Pharmacol Res
  doi: 10.1016/j.phrs.2013.07.009
– volume: 11
  start-page: 1
  year: 2019
  ident: B476
  article-title: The Role and Mechanisms of Action of microRNAs in Cancer Drug Resistance
  publication-title: Clin Epigenet
  doi: 10.1186/s13148-018-0587-8
– volume: 162
  start-page: 45
  year: 2012
  ident: B403
  article-title: Nanotechnology Applied to Overcome Tumor Drug Resistance
  publication-title: J Controlled Release
  doi: 10.1016/j.jconrel.2012.05.051
– volume: 34
  year: 2015
  ident: B319
  article-title: Emerging Strategies for Cancer Immunoprevention
  publication-title: Oncogene 2015 34:50
  doi: 10.1038/onc.2015.98
– volume: 1
  start-page: 8
  year: 2010
  ident: B118
  article-title: Epigenetics: A New Bridge Between Nutrition and Health
  publication-title: Adv Nutr
  doi: 10.3945/an.110.1004
– volume: 125
  year: 2010
  ident: B370
  article-title: Formation of Procoagulant Microparticles and Properties
  publication-title: Thromb Res
  doi: 10.1016/j.thromres.2010.01.036
– volume: 107
  start-page: 1
  year: 2001
  ident: B160
  article-title: HIF-1, O2, and the 3 PHDs: How Animal Cells Signal Hypoxia to the Nucleus
  publication-title: Cell
  doi: 10.1016/S0092-8674(01)00518-9
– volume: 66
  year: 2019
  ident: B175
  article-title: The Combination Therapy of HIF1α Inhibitor LW6 and Cisplatin Plays an Effective Role on Anti-Tumor Function in A549 Cells
  publication-title: Neoplasma
  doi: 10.4149/neo_2018_180921N708
– volume: 27
  year: 2009
  ident: B44
  article-title: Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing P53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells
  publication-title: Stem Cells
  doi: 10.1002/stem.154
– volume: 13
  year: 2019
  ident: B20
  article-title: Innovative Approaches for Cancer Treatment: Current Perspectives and New Challenges
  publication-title: Ecancermedicalscience
  doi: 10.3332/ecancer.2019.961
– volume: 319
  year: 1986
  ident: B146
  article-title: Similarity of Protein Encoded by the Human C-Erb-B-2 Gene to Epidermal Growth Factor Receptor
  publication-title: Nature
  doi: 10.1038/319230a0
– volume: 5
  start-page: 1
  year: 2015
  ident: B188
  article-title: Hypoxia-Induced Autophagy Mediates Cisplatin Resistance in Lung Cancer Cells
  publication-title: Sci Rep
  doi: 10.1038/srep12291
– volume: 39
  start-page: 1
  year: 2016
  ident: B353
  article-title: Immune Suppressive Mechanisms in the Tumor Microenvironment
  publication-title: Curr Opin Immunol
  doi: 10.1016/j.coi.2015.10.009
– volume: 29
  year: 1996
  ident: B13
  article-title: Effects of Hypoxia on Drug Resistance Phenotype and Genotype in Human Glioma Cell Lines
  publication-title: J Neurooncol
  doi: 10.1007/BF00182138
– volume: 58
  year: 2017
  ident: B438
  article-title: pH-Sensitive Polymeric Nanoparticles for Co-Delivery of Doxorubicin and Curcumin to Treat Cancer via Enhanced Pro-Apoptotic and Anti-Angiogenic Activities
  publication-title: Acta Biomater
  doi: 10.1016/j.actbio.2017.04.029
– volume: 367
  year: 2006
  ident: B328
  article-title: Sustained Efficacy Up to 4.5 Years of a Bivalent L1 Virus-Like Particle Vaccine Against Human Papillo-Mavirus Types 16 and 18: Follow-Up From a Randomised Control Trial
  publication-title: Lancet
  doi: 10.1016/S0140-6736(06)68439-0
– volume: 7
  start-page: 187
  year: 2012
  ident: B440
  article-title: Bypassing Multidrug Resistance in Human Breast Cancer Cells With Lipid/Polymer Particle Assemblies
  publication-title: Int J Nanomedicine
  doi: 10.2147/IJN.S27864
– volume: 10
  year: 2009
  ident: B60
  article-title: ABC Transporters: The Power to Change
  publication-title: Nat Rev Mol Cell Biol
  doi: 10.1038/nrm2646
– volume: 4
  start-page: e183267
  year: 2018
  ident: B350
  article-title: Assessment of Safety and Immunogenicity of PVX-410 Vaccine With or Without Lenalidomide in Patients With Smoldering Multiple Myeloma: A Nonrandomized Clinical Trial
  publication-title: JAMA Oncol
  doi: 10.1001/jamaoncol.2018.3267
– volume: 12
  year: 2006
  ident: B279
  article-title: In Vitro Drug Sensitivity Predicts Response and Survival After Individualized Sensitivity-Directed Chemotherapy in Metastatic Melanoma: A Multicenter Phase II Trial of the Dermatologic Cooperative Oncology Group
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-05-2763
– volume: 22
  year: 2002
  ident: B284
  article-title: Cell Viability Assay for Drug Testing in Ovarian Cancer: In Vitro Kill Versus Clinical Response
  publication-title: Anticancer Res
– volume: 5
  year: 2014
  ident: B114
  article-title: Correlation of Long Non-Coding RNA Expression With Metastasis, Drug Resistance and Clinical Outcome in Cancer
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.2469
– volume: 26
  year: 2014
  ident: B85
  article-title: Drug Resistance via Feedback Activation of Stat3 in Oncogene-Addicted Cancer Cells
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2014.05.019
– volume: 123
  year: 2008
  ident: B131
  article-title: miR-15b and miR-16 Modulate Multidrug Resistance by Targeting BCL2 in Human Gastric Cancer Cells
  publication-title: Int J Cancer
  doi: 10.1002/ijc.23501
– start-page: 1227670
  volume-title: Variable Clonal Repopulation Dynamics Influence
  year: 2012
  ident: B45
  article-title: Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer Resp
– volume: 15
  year: 2009
  ident: B195
  article-title: Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2009.03.018
– volume: 23
  year: 2009
  ident: B303
  article-title: Membrane Microparticles Mediate Transfer of P-Glycoprotein to Drug Sensitive Cancer Cells
  publication-title: Leukemia
  doi: 10.1038/leu.2009.76
– volume: 54
  year: 1993
  ident: B12
  article-title: The Effect of Hypoxia on Acquired Drug Resistance and Response to Epidermal Growth Factor in Chinese Hamster Lung Fibroblasts and Human Breast-Cancer Cells In Vitro
  publication-title: Int J Cancer
  doi: 10.1002/ijc.2910540421
– volume: 47
  start-page: 47
  year: 2019
  ident: B61
  article-title: Structural Biology and Structure–Function Relationships of Membrane Proteins
  publication-title: Biochem Soc Trans
  doi: 10.1042/BST20180269
– volume: 4
  year: 2014
  ident: B87
  article-title: A Melanoma Cell State Distinction Influences Sensitivity to MAPK Pathway Inhibitors
  publication-title: Cancer Discov
  doi: 10.1158/2159-8290.CD-13-0424
– volume: 3
  year: 2004
  ident: B263
  article-title: Gefitinib Reverses Breast Cancer Resistance Protein–Mediated Drug Resistance
  publication-title: Mol Cancer Ther
  doi: 10.1158/1535-7163.1119.3.9
– volume: 3
  start-page: 1600
  year: 2012
  ident: B213
  article-title: Autophagy-Related Gene 12 (ATG12) is a Novel Determinant of Primary Resistance to HER2-Targeted Therapies: Utility of Transcriptome Analysis of the Autophagy Interactome to Guide Breast Cancer Treatment
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.742
– volume: 19
  year: 2017
  ident: B411
  article-title: Aptamer-Conjugated Chitosan-Anchored Liposomal Complexes for Targeted Delivery of Erlotinib to EGFR-Mutated Lung Cancer Cells
  publication-title: AAPS J
  doi: 10.1208/s12248-017-0057-9
– volume: 60
  year: 2000
  ident: B364
  article-title: Immunoprevention of Cancer: Is the Time Ripe
  publication-title: Cancer Res
– volume: 107
  year: 2006
  ident: B32
  article-title: Pharmacodynamics of Cytarabine Alone and in Combination With 7-Hydroxystaurosporine (UCN-01) in AML Blasts In Vitro and During a Clinical Trial
  publication-title: Blood
  doi: 10.1182/blood-2005-08-3351
– volume: 84
  year: 1987
  ident: B167
  article-title: Frequencies of Independent and Simultaneous Selection of Chinese Hamster Cells for Methotrexate and Doxorubicin (Adriamycin) Resistance
  publication-title: Proc Natl Acad Sci
  doi: 10.1073/pnas.84.24.9261
– volume: 509
  year: 2014
  ident: B452
  article-title: High-Throughput Screening of a CRISPR/Cas9 Library for Functional Genomics in Human Cells
  publication-title: Nature
  doi: 10.1038/nature13166
– volume: 118
  year: 2012
  ident: B332
  article-title: HER-2 Pulsed Dendritic Cell Vaccine can Eliminate HER-2 Expression and Impact Ductal Carcinoma in Situ
  publication-title: Cancer
  doi: 10.1002/cncr.26734
– ident: B16
– volume: 347
  year: 2014
  ident: B229
  article-title: Multi-Drug Resistance in Cancer Chemotherapeutics: Mechanisms and Lab Approaches
  publication-title: Cancer Lett
  doi: 10.1016/j.canlet.2014.03.013
– volume: 18
  year: 1999
  ident: B192
  article-title: Role of P53 and P21 Waf1/Cip1 in Senescence-Like Terminal Proliferation Arrest Induced in Human Tumor Cells by Chemotherapeutic Drugs
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1203078
– volume: 24
  year: 2010
  ident: B269
  article-title: Targeting Lysosomes to Eradicate Imatinib-Resistant Chronic Myelogenous Leukemia Cells
  publication-title: Leukemia
  doi: 10.1038/leu.2010.55
– volume: 10
  start-page: 44
  year: 2015
  ident: B280
  article-title: Anticancer Drug Sensitivity Testing, a Historical Review and Future Perspectives
  publication-title: Curr Drug Ther
  doi: 10.2174/157488551001150825100450
– volume: 1
  year: 2015
  ident: B346
  article-title: The Evolving Landscape of HER2 Targeting in Breast Cancer
  publication-title: JAMA Oncol
  doi: 10.1001/jamaoncol.2015.2286
– volume: 53
  year: 2002
  ident: B247
  article-title: MDR1 Gene Polymorphisms and Disposition of the P-Glycoprotein Substrate Fexofenadine
  publication-title: Br J Clin Pharmacol
  doi: 10.1046/j.1365-2125.2002.01591.x
– volume: 73
  year: 2013
  ident: B130
  article-title: miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-12-3308
– volume: 59
  year: 2006
  ident: B100
  article-title: Neonatal Dubin-Johnson Syndrome: Long-Term Follow-Up and MRP2 Mutations Study
  publication-title: Pediatr Res
  doi: 10.1203/01.pdr.0000203093.10908.bb
– volume: 8
  start-page: 4
  year: 2002
  ident: B72
  article-title: Membrane Transport of Chemotherapeutics and Drug Resistance: Beyond the ABC Family of Exporters to the Role of Carrier-Mediated Processes
  publication-title: Clin Cancer Res
– ident: B105
– volume: 38
  year: 2012
  ident: B120
  article-title: Microparticles and Their Emerging Role in Cancer Multidrug Resistance
  publication-title: Cancer Treat Rev
  doi: 10.1016/j.ctrv.2011.06.005
– volume: 26
  year: 2020
  ident: B340
  article-title: Immune Activation in Mismatch Repair–Deficient Carcinogenesis: More Than Just Mutational Rate
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-18-0856
– volume: 7
  year: 2012
  ident: B307
  article-title: Docetaxel-Resistance in Prostate Cancer: Evaluating Associated Phenotypic Changes and Potential for Resistance Transfer via Exosomes
  publication-title: PLos One
  doi: 10.1371/journal.pone.0050999
– volume: 8
  start-page: 107500
  year: 2017
  ident: B217
  article-title: MicroRNA-410-3p Attenuates Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma by Inhibiting HMGB1-Mediated Autophagy
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.22494
– volume: 279
  year: 2012
  ident: B128
  article-title: MicroRNA-199a Targets CD44 to Suppress the Tumorigenicity and Multidrug Resistance of Ovarian Cancer-Initiating Cells
  publication-title: FEBS J
  doi: 10.1111/J.1742-4658.2012.08589.X
– year: 1979
  ident: B46
  article-title: Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA
  publication-title: Science
  doi: 10.1126/science.1241328
– volume: 140
  year: 2017
  ident: B338
  article-title: Transient Immunological and Clinical Effectiveness of Treating Mice Bearing Premalignant Oral Lesions With PD-1 Antibodies
  publication-title: Int J Cancer
  doi: 10.1002/ijc.30543
– volume-title: Assay Guidance Manual. Eli Lilly & Company and the National Center for Advancing Translational Sciences
  year: 2014
  ident: B268
  article-title: “High Content Screening With Primary Neurons.,”
– volume: 10
  year: 2018
  ident: B469
  article-title: Immunity to CRISPR Cas9 and Cas12a Therapeutics
  publication-title: Wiley Interdiscip Reviews: Syst Biol Med
  doi: 10.1002/wsbm.1408
– volume: 65
  year: 2013
  ident: B405
  article-title: Nanomedicine Therapeutic Approaches to Overcome Cancer Drug Resistance
  publication-title: Adv Drug Delivery Rev
  doi: 10.1016/j.addr.2013.09.019
– volume: 8
  year: 2012
  ident: B418
  article-title: Gold-Doxorubicin Nanoconjugates for Overcoming Multidrug Resistance
  publication-title: Nanomedicine: Nanotechnol Biol Med
  doi: 10.1016/j.nano.2011.06.005
– volume: 98
  year: 2018
  ident: B465
  article-title: Genome-Wide CRISPR Screen Reveals SGOL1 as a Druggable Target of Sorafenib-Treated Hepatocellular Carcinoma
  publication-title: Lab Invest
  doi: 10.1038/s41374-018-0027-6
– volume: 6
  start-page: 295
  year: 2006
  ident: B124
  article-title: Regulation of Multidrug Resistance by Pro-Inflammatory Cytokines
  publication-title: Curr Cancer Drug Targets
  doi: 10.2174/156800906777441753
– volume: 11
  start-page: 293
  year: 2019
  ident: B111
  article-title: Mutant P53 in Cancer Therapy – The Barrier or the Path
  publication-title: J Mol Cell Biol
  doi: 10.1093/jmcb/mjy072
– volume: 8
  year: 2013
  ident: B425
  article-title: Silver-Based Nanoparticles Induce Apoptosis in Human Colon Cancer Cells Mediated Through P53
  publication-title: Nanomedicine
  doi: 10.2217/nnm.12.176
– volume: 12
  year: 2017
  ident: B459
  article-title: Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity
  publication-title: ACS Chem Biol
  doi: 10.1021/acschembio.7b00147
– volume: 65
  start-page: 596
  year: 2005
  ident: B264
  article-title: Estrogen-Mediated Post Transcriptional Down-Regulation of Breast Cancer Resistance Protein/Abcg2
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.596.65.2
– volume: 3
  year: 2003
  ident: B351
  article-title: Cancer Vaccines: Between the Idea and the Reality
  publication-title: Nat Rev Immunol
  doi: 10.1038/nri1150
– volume: 23
  year: 2017
  ident: B466
  article-title: PARP Inhibitor Activity Correlates With Slfn11 Expression and Demonstrates Synergy With Temozolomide in Small Cell Lung Cancer
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-16-1040
– volume: 77
  year: 2010
  ident: B422
  article-title: Signaling Gene Cascade in Silver Nanoparticle Induced Apoptosis
  publication-title: Colloids Surfaces B: Biointerf
  doi: 10.1016/j.colsurfb.2010.01.033
– volume: 2
  year: 2015
  ident: B69
  article-title: Mechanisms of Drug Resistance in Veterinary Oncology
  publication-title: Vet Sci
  doi: 10.3390/vetsci2030150
– volume: 39
  year: 2016
  ident: B26
  article-title: Cancer Immunoprevention
  publication-title: Curr Opin Immunol
  doi: 10.1016/j.coi.2016.01.002
– volume: 3
  start-page: 1
  year: 2012
  ident: B103
  article-title: Human ABCG2: Structure, Function, and Its Role in Multidrug Resistance
  publication-title: Int J Biochem Mol Biol
– volume: 342
  year: 2013
  ident: B55
  article-title: Fueling Immunity: Insights Into Metabolism and Lymphocyte Function
  publication-title: Science (1979)
  doi: 10.1126/science.1242454
– ident: B233
– volume: 82
  year: 2004
  ident: B345
  article-title: MUC1 Immunobiology: From Discovery to Clinical Applications
  publication-title: Adv Immunol
  doi: 10.1016/S0065-2776(04)82006-6
– volume: 17
  year: 2017
  ident: B102
  article-title: Pharmacogenetics of ABCB5, ABCC5 and RLIP76 and Doxorubicin Pharmacokinetics in Asian Breast Cancer Patients
  publication-title: Pharmacogenomics J
  doi: 10.1038/tpj.2016.17
– volume: 9
  start-page: 22113
  year: 2018
  ident: B228
  article-title: Autophagy-Deficient Breast Cancer Shows Early Tumor Recurrence and Escape From Dormancy
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.25197
– volume: 351
  year: 2014
  ident: B56
  article-title: Extracellular ATP Is Internalized by Macropinocytosis and Induces Intracellular ATP Increase and Drug Resistance in Cancer Cells
  publication-title: Cancer Lett
  doi: 10.1016/j.canlet.2014.06.008
– volume: 5
  start-page: 3
  year: 2017
  ident: B352
  article-title: Myeloid-Derived Suppressor Cells
  publication-title: Cancer Immunol Res
  doi: 10.1158/2326-6066.CIR-16-0297
– volume: 8
  year: 2017
  ident: B110
  article-title: The Role of P53 in Cancer Drug Resistance and Targeted Chemotherapy
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.13475
– volume: 126
  year: 2016
  ident: B196
  article-title: The Impact of Hypoxia on Tumor-Associated Macrophages
  publication-title: J Clin Invest
  doi: 10.1172/JCI84427
– volume: 285
  year: 2010
  ident: B413
  article-title: Multifunctional Nanoparticles Delivering Small Interfering RNA and Doxorubicin Overcome Drug Resistance in Cancer
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M110.125906
– volume: 15
  year: 2008
  ident: B177
  article-title: Effects of Lentivirus-Mediated HIF-1α Knockdown on Hypoxia-Related Cisplatin Resistance and Their Dependence on P53 Status in Fibrosarcoma Cells
  publication-title: Cancer Gene Ther
  doi: 10.1038/cgt.2008.4
– volume: 13
  year: 2012
  ident: B23
  article-title: Implication of Tumor Microenvironment in Chemoresistance: Tumor-Associated Stromal Cells Protect Tumor Cells From Cell Death
  publication-title: Int J Mol Sci
  doi: 10.3390/ijms13089545
– volume: 7
  year: 1995
  ident: B139
  article-title: Tumor-Necrosis-Factor and DNA Topoisomerase-Ii Inhibitors in Human Ovarian-Cancer-Potential Role in Chemotherapy
  publication-title: Int J Oncol
  doi: 10.3892/ijo.7.3.461
– volume: 42
  year: 2018
  ident: B206
  article-title: MicroRNA-1 Overexpression Increases Chemosensitivity of non-Small Cell Lung Cancer Cells by Inhibiting Autophagy Related 3-Mediated Autophagy
  publication-title: Cell Biol Int
  doi: 10.1002/cbin.10995
– volume: 18
  start-page: 82
  year: 2019
  ident: B208
  article-title: Long non-Coding RNA GBCDRlnc1 Induces Chemoresistance of Gallbladder Cancer Cells by Activating Autophagy
  publication-title: Mol Cancer
  doi: 10.1186/s12943-019-1016-0
– volume: 32
  start-page: 1
  year: 2013
  ident: B145
  article-title: Function of Oncogenes in Cancer Development
  publication-title: EMBO J
  doi: 10.1038/emboj.2013.97
– volume: 13
  start-page: 35
  year: 2004
  ident: B240
  article-title: Functional Annotation of a Novel NFKB1 Promoter Polymorphism That Increases Risk for Ulcerative Colitis
  publication-title: Hum Mol Genet
  doi: 10.1093/hmg/ddh008
– volume: 119
  year: 2012
  ident: B68
  article-title: Purinergic Signaling Inhibits Human Acute Myeloblastic Leukemia Cell Proliferation, Migration, and Engraftment in Immunodeficient Mice
  publication-title: Blood
  doi: 10.1182/blood-2011-07-370775
– volume: 22
  year: 2003
  ident: B63
  article-title: The Role of Glutathione-S-Transferase in Anti-Cancer Drug Resistance
  publication-title: Oncogene
  doi: 10.1038/sj.onc.1206940
– volume: 3
  year: 2010
  ident: B334
  article-title: Vaccine Against MUC1 Antigen Expressed in Inflammatory Bowel Disease and Cancer Lessens Colonic Inflammation and Prevents Progression to Colitis-Associated Colon Cancer
  publication-title: Cancer Prev Res
  doi: 10.1158/1940-6207.CAPR-09-0194
– volume: 721
  year: 2013
  ident: B373
  article-title: Microparticle Drug Sequestration Provides a Parallel Pathway in the Acquisition of Cancer Drug Resistance
  publication-title: Eur J Pharmacol
  doi: 10.1016/j.ejphar.2013.09.044
– volume: 2
  start-page: 48
  year: 2002
  ident: B169
  article-title: Multidrug Resistance in Cancer: Role of ATP–dependent Transporters
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc706
– volume: 4
  year: 2013
  ident: B30
  article-title: Mechanisms and Insights Into Drug Resistance in Cancer
  publication-title: Front Pharmacol
  doi: 10.3389/FPHAR.2013.00028
– volume: 6
  start-page: 18
  year: 2013
  ident: B337
  article-title: MUC1 Vaccine for Individuals With Advanced Adenoma of the Colon: A Cancer Immunoprevention Feasibility Study
  publication-title: Cancer Prev Res
  doi: 10.1158/1940-6207.CAPR-12-0275
– volume: 7
  start-page: 61136
  year: 2016
  ident: B444
  article-title: The Histone Methyltransferase G9a as a Therapeutic Target to Override Gemcitabine Resistance in Pancreatic Cancer
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.11256
– volume-title: “IL-2 Gene Transfer for Chemosensitization of Multidrug-Resistant Human Colon Carcinoma Cells BT - Gene Therapy of Cancer.,”
  year: 1998
  ident: B141
– volume: 22
  year: 2012
  ident: B249
  article-title: Emodin As an Effective Agent in Targeting Cancer Stem-Like Side Population Cells of Gallbladder Carcinoma
  publication-title: Stem Cells Dev
  doi: 10.1089/scd.2011.0709
– volume: 253
  start-page: 37
  year: 2017
  ident: B410
  article-title: Characterization of Pegylated and non-Pegylated Liposomal Formulation for the Delivery of Hypoxia Activated Vinblastine-N-Oxide for the Treatment of Solid Tumors
  publication-title: J Controlled Release
  doi: 10.1016/j.jconrel.2017.03.022
– volume: 1
  start-page: 78
  year: 2008
  ident: B242
  article-title: Mouse Xenograft Models vs GEM Models for Human Cancer Therapeutics
  publication-title: DMM Dis Models Mech
  doi: 10.1242/dmm.000976
– volume: 26
  start-page: 40
  year: 2019
  ident: B454
  article-title: Material Solutions for Delivery of CRISPR/Cas-Based Genome Editing Tools: Current Status and Future Outlook
  publication-title: Mater Today
  doi: 10.1016/j.mattod.2018.12.003
– volume: 26
  year: 2016
  ident: B393
  article-title: Reversing Drug Resistance of Soft Tumor-Repopulating Cells by Tumor Cell-Derived Chemotherapeutic Microparticles
  publication-title: Cell Res
  doi: 10.1038/cr.2016.53
– volume: 5
  year: 2010
  ident: B178
  article-title: Hypoxia-Inducible Factor 1α Determines Gastric Cancer Chemosensitivity via Modulation of P53 and NF-κb
  publication-title: PLos One
  doi: 10.1371/journal.pone.0012038
– volume: 14
  start-page: 191
  year: 2011
  ident: B166
  article-title: Hypoxia-Mediated Drug Resistance: Novel Insights on the Functional Interaction of HIFs and Cell Death Pathways
  publication-title: Drug Resist Updates
  doi: 10.1016/j.drup.2011.03.001
– volume: 481
  year: 2012
  ident: B49
  article-title: Clonal Evolution in Relapsed Acute Myeloid Leukaemia Revealed by Whole-Genome Sequencing
  publication-title: Nature
  doi: 10.1038/nature10738
– volume: 11
  year: 2011
  ident: B58
  article-title: Otto Warburg’s Contributions to Current Concepts of Cancer Metabolism
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc3038
– volume: 11
  year: 2019
  ident: B397
  article-title: Autologous Tumor Cell–Derived Microparticle-Based Targeted Chemotherapy in Lung Cancer Patients With Malignant Pleural Effusion
  publication-title: Sci Transl Med
  doi: 10.1126/scitranslmed.aat5690
– volume: 56
  year: 2013
  ident: B246
  article-title: Optimization of Novel Indole-2-Carboxamide Inhibitors of Neurotropic Alphavirus Replication
  publication-title: J Medicinal Chem
  doi: 10.1021/jm401330r
– volume: 33
  year: 2012
  ident: B428
  article-title: Co-Delivery of Paclitaxel and Survivin shRNA by Pluronic P85-PEI/TPGS Complex Nanoparticles to Overcome Drug Resistance in Lung Cancer
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2012.08.007
– volume: 207
  year: 2018
  ident: B207
  article-title: Salinomycin-Induced Autophagy Blocks Apoptosis via the ATG3/AKT/mTOR Signaling Axis in PC-3 Cells
  publication-title: Life Sci
  doi: 10.1016/j.lfs.2018.06.034
– start-page: 1
  volume-title: Personalized Cancer Chemotherapy
  year: 2014
  ident: B292
  article-title: Personalized Cancer Chemotherapy: An Effective Way of Enhancing Outcomes in Clinics
– volume: 501
  start-page: 328
  year: 2013
  ident: B42
  article-title: Tumor Heterogeneity and Cancer Cell Plasticity
  publication-title: Nature
  doi: 10.1038/NATURE12624
– ident: B104
– volume: 21
  start-page: 69
  year: 2004
  ident: B248
  article-title: Exploring the Quantitative Relationship Between the Level of MDR1 Transcript, Protein and Function Using Digoxin as a Marker of MDR1-Dependent Drug Efflux Activity
  publication-title: Eur J Pharm Sci
  doi: 10.1016/S0928-0987(03)00204-5
– volume: 2
  year: 2012
  ident: B288
  article-title: Challenges and Limitations of Targeting Cancer Stem Cells and/or the Tumour Microenvironment
  publication-title: Drugs Ther Stud
  doi: 10.4081/dts.2012.e10
– volume: 113
  year: 2012
  ident: B125
  article-title: Identification of Cancer Stem Cells in Vincristine Preconditioned SGC7901 Gastric Cancer Cell Line
  publication-title: J Cell Biochem
  doi: 10.1002/JCB.23356
– volume: 7
  start-page: 38
  year: 2017
  ident: B122
  article-title: Regulation of Multidrug Resistance by microRNAs in Anti-Cancer Therapy
  publication-title: Acta Pharm Sin B
  doi: 10.1016/j.apsb.2016.09.002
– volume: 36
  year: 2017
  ident: B223
  article-title: LncRNA HULC Triggers Autophagy via Stabilizing Sirt1 and Attenuates the Chemosensitivity of HCC Cells
  publication-title: Oncogene
  doi: 10.1038/onc.2016.521
– volume: 77
  start-page: 491
  year: 1994
  ident: B257
  article-title: Disruption of the Mouse Mdr1a P-Glycoprotein Gene Leads to a Deficiency in the Blood-Brain Barrier and to Increased Sensitivity to Drugs
  publication-title: Cell
  doi: 10.1016/0092-8674(94)90212-7
– volume: 110
  year: 2014
  ident: B92
  article-title: Phase I Study of Panobinostat and Imatinib in Patients With Treatment-Refractory Metastatic Gastrointestinal Stromal Tumors
  publication-title: Br J Cancer
  doi: 10.1038/bjc.2013.826
– volume: 31
  year: 2012
  ident: B91
  article-title: Candidate DNA Methylation Drivers of Acquired Cisplatin Resistance in Ovarian Cancer Identified by Methylome and Expression Profiling
  publication-title: Oncogene
  doi: 10.1038/onc.2011.611
– volume: 4
  year: 1998
  ident: B378
  article-title: The Involvement of Calpain-Independent Proteolysis of the Tumor Suppressor NF2 (Merlin) in Schwannomas and Meningiomas
  publication-title: Nat Med
  doi: 10.1038/nm0898-915
– volume: 110
  year: 2014
  ident: B93
  article-title: A Randomised, Phase II Trial of the DNA-Hypomethylating Agent 5-Aza-2′-Deoxycytidine (Decitabine) in Combination With Carboplatin vs Carboplatin Alone in Patients With Recurrent, Partially Platinum-Sensitive Ovarian Cancer
  publication-title: Br J Cancer
  doi: 10.1038/bjc.2014.116
– volume: 2
  start-page: 41
  year: 2014
  ident: B289
  article-title: Dynamic Interactions Between Cancer Stem Cells and Their Stromal Partners
  publication-title: Curr Pathobiol Rep
  doi: 10.1007/s40139-013-0036-5
– volume: 5
  year: 1999
  ident: B261
  article-title: Rapid Activation of MDR1 Gene Expression in Human Metastatic Sarcoma After in Vivo Exposure to Doxorubicin
  publication-title: Clin Cancer Res
– volume: 507
  year: 2018
  ident: B316
  article-title: Exosomal Transfer of miR-214 Mediates Gefitinib Resistance in non-Small Cell Lung Cancer
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/j.bbrc.2018.11.061
– volume: 455
  year: 1976
  ident: B77
  article-title: A Surface Glycoprotein Modulating Drug Permeability in Chinese Hamster Ovary Cell Mutants
  publication-title: BBA - Biomembranes
  doi: 10.1016/0005-2736(76)90160-7
– volume: 27
  year: 2015
  ident: B89
  article-title: Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments With High Integrin β1/FAK Signaling
  publication-title: Cancer Cell
  doi: 10.1016/j.ccell.2015.03.008
– volume: 86
  year: 1989
  ident: B147
  article-title: Experimental Approaches to Hypothetical Hormones : Detection of a Candidate Ligand of the Neu Protooncogene
  doi: 10.1073/pnas.86.9.3179
– volume: 10
  year: 2004
  ident: B387
  article-title: Effect of Ticlopidine on Monocyte-Derived Microparticles and Activated Platelet Markers in Diabetes Mellitus
  publication-title: Clin Appl Thromb/Hemostasis
  doi: 10.1177/107602960401000207
– volume: 368
  year: 2013
  ident: B81
  article-title: Acquired Resistance to Crizotinib From a Mutation in CD74 – Ros1
  publication-title: N Engl J Med
  doi: 10.1056/nejmoa1215530
– volume: 5
  year: 2013
  ident: B107
  article-title: Multiple Functions of BCL-2 Family Proteins
  publication-title: Cold Spring Harbor Perspect Biol
  doi: 10.1101/cshperspect.a008722
– volume: 8
  year: 2013
  ident: B384
  article-title: A Rac1/Cdc42 GTPase-Specific Small Molecule Inhibitor Suppresses Growth of Primary Human Prostate Cancer Xenografts and Prolongs Survival in Mice
  publication-title: PLos One
  doi: 10.1371/journal.pone.0074924
– volume: 2
  start-page: 141
  year: 2019
  ident: B41
  article-title: Drug Resistance and Combating Drug Resistance in Cancer
  publication-title: Cancer Drug Resist PNAS USA
  doi: 10.20517/CDR.2019.10
– volume: 2
  year: 2006
  ident: B98
  article-title: Structure and Function of the MRP2 (ABCC2) Protein and Its Role in Drug Disposition
  publication-title: Expert Opin Drug Metab Toxicol
  doi: 10.1517/17425255.2.3.351
– volume: 266
  year: 2017
  ident: B211
  article-title: Co-Delivery of Autophagy Inhibitor ATG7 siRNA and Docetaxel for Breast Cancer Treatment
  publication-title: J Controlled Release
  doi: 10.1016/j.jconrel.2017.09.042
– volume: 160
  year: 2012
  ident: B406
  article-title: Doxil®—the First FDA-Approved Nano-Drug: Lessons Learned
  publication-title: J Controlled Release
  doi: 10.1016/j.jconrel.2012.03.020
– volume: 20
  year: 2013
  ident: B333
  article-title: Response to HER-2 Pulsed DC1 Vaccines is Predicted by Both HER-2 and Estrogen Receptor Expression in DCIS
  publication-title: Ann Surg Oncol
  doi: 10.1245/s10434-013-3119-y
– volume: 10
  year: 2020
  ident: B4
  article-title: Plasma Exosomal miRNA Expression Profile as Oxaliplatin-Based Chemoresistant Biomarkers in Colorectal Adenocarcinoma
  publication-title: Front Oncol
  doi: 10.3389/fonc.2020.01495
– volume: 331
  start-page: 1
  year: 2020
  ident: B165
  article-title: Nrf2 Activation Protects Auditory Hair Cells From Cisplatin-Induced Ototoxicity Independent on Mitochondrial ROS Production
  publication-title: Toxicol Lett
  doi: 10.1016/j.toxlet.2020.04.005
– volume: 32
  year: 2013
  ident: B293
  article-title: The MUC4 Mucin Mediates Gemcitabine Resistance of Human Pancreatic Cancer Cells via the Concentrative Nucleoside Transporter Family
  publication-title: Oncogene
  doi: 10.1038/onc.2012.179
– volume: 58
  start-page: 296
  year: 2010
  ident: B323
  article-title: Hepatitis B Vaccination in Children: The Taiwan Experience
  publication-title: Pathologie Biologie
  doi: 10.1016/j.patbio.2009.11.002
– volume: 53
  year: 2018
  ident: B313
  article-title: Exosome-Mediated Transfer of lncRNA RP11 838n2
  publication-title: 4 Promotes Erlotinib resista Non Small Cell Lung Cancer Int J Oncol
  doi: 10.3892/ijo.2018.4412
– volume: 45
  year: 2020
  ident: B398
  article-title: Codelivery of Survivin Inhibitor and Chemotherapeutics by Tumor-Derived Microparticles to Reverse Multidrug Resistance in Osteosarcoma
  publication-title: Cell Biol Int
  doi: 10.1002/cbin.11494
– volume: 7
  year: 2018
  ident: B341
  article-title: Blockade of PD-1 Effectively Inhibits In Vivo Malignant Transformation of Oral Mucosa
  publication-title: Oncoimmunology
  doi: 10.1080/2162402X.2017.1388484
– volume: 26
  year: 2014
  ident: B446
  article-title: Doxorubicin-Loaded Magnetic Silk Fibroin Nanoparticles for Targeted Therapy of Multidrug-Resistant Cancer
  publication-title: Adv Mater
  doi: 10.1002/adma.201403562
– volume: 58
  year: 1989
  ident: B8
  article-title: The Biochemistry of P-Glycoprotein-Mediated Multidrug Resistance
  publication-title: Annu Rev Biochem
  doi: 10.1146/annurev.bi.58.070189.001033
– volume: 132
  year: 2001
  ident: B80
  article-title: HMG-CoA Reductase Inhibitors and P-Glycoprotein Modulation
  publication-title: Br J Pharmacol
  doi: 10.1038/sj.bjp.0703920
– volume: 181
  start-page: 85
  year: 2009
  ident: B322
  article-title: Cancer Prevention by Vaccination Against Hepatitis B
  publication-title: Cancer Prev II
  doi: 10.1007/978-3-540-69297-3_10
– volume: 7
  year: 2005
  ident: B193
  article-title: The Identification of Senescence-Specific Genes During the Induction of Senescence in Prostate Cancer Cells
  publication-title: Neoplasia
  doi: 10.1593/neo.05250
– volume: 62
  year: 2002
  ident: B191
  article-title: DNA Damage is Able to Induce Senescence in Tumor Cells In Vitro and In Vivo
  publication-title: Cancer Res
– volume: 10
  year: 1992
  ident: B149
  article-title: Prognostic Importance of c-erbB-2 Expression in Breast Cancer
  publication-title: J Clin Oncol
  doi: 10.1200/JCO.1992.10.7.1049
– volume: 42
  year: 2001
  ident: B97
  article-title: The Human ATP-Binding Cassette (ABC) Transporter Superfamily
  publication-title: J Lipid Res
  doi: 10.1101/gr.184901
– volume: 1
  year: 2017
  ident: B434
  article-title: Clinical Application of Polymeric Micelles for the Treatment of Cancer
  publication-title: Mater Chem Front
  doi: 10.1039/C6QM00289G
– volume: 19
  year: 2018
  ident: B106
  article-title: Bcl-2 Inhibition to Overcome Resistance to Chemo-and Immunotherapy
  publication-title: Int J Mol Sci
  doi: 10.3390/ijms19123950
– volume: 106
  start-page: djt347
  year: 2014
  ident: B294
  article-title: Pancreatic Cancer Hent1 Expression and Survival From Gemcitabine in Patients From the ESPAC-3 Trial
  publication-title: J Natl Cancer Inst
  doi: 10.1093/jnci/djt347
– volume: 200
  year: 2018
  ident: B354
  article-title: Myeloid-Derived Suppressor Cells: Immune-Suppressive Cells That Impair Antitumor Immunity and are Sculpted by Their Environment
  publication-title: J Immunol
  doi: 10.4049/jimmunol.1701019
– volume: 20
  year: 2006
  ident: B38
  article-title: Tumor Microenvironment and Drug Resistance in Hematologic Malignancies
  publication-title: Blood Rev
  doi: 10.1016/J.BLRE.2005.08.003
– year: 2017
  ident: B112
  article-title: Acquired Resistance With Epigenetic Alterations Under Long-Term Anti-Angiogenic Therapy for Hepatocellular Carcinoma
  publication-title: Mol Cancer Ther
  doi: 10.1158/1535-7163.MCT-16-0728
– volume: 452
  year: 2013
  ident: B432
  article-title: Enhanced Antitumor Efficacy by Methotrexate Conjugated Pluronic Mixed Micelles Against KBv Multidrug Resistant Cancer
  publication-title: Int J Pharm
  doi: 10.1016/j.ijpharm.2013.05.015
– volume: 6
  start-page: 1
  year: 2016
  ident: B447
  article-title: Arsenite-Loaded Nanoparticles Inhibit PARP-1 to Overcome Multidrug Resistance in Hepatocellular Carcinoma Cells
  publication-title: Sci Rep
  doi: 10.1038/srep31009
– volume: 17
  year: 1999
  ident: B376
  article-title: Matrix-Degrading Proteinases are Shed in Membrane Vesicles by Ovarian Cancer Cells In Vivo and In Vitro
  publication-title: Clin Exp Metastasis
  doi: 10.1023/A:1006500406240
– volume: 8
  year: 1996
  ident: B366
  article-title: Oncogenic Proteins as Tumor Antigens
  publication-title: Curr Opin Immunol
  doi: 10.1016/S0952-7915(96)80079-3
– volume: 9
  year: 1998
  ident: B285
  article-title: Use of an Ex Vivo ATP Luminescence Assay to Direct Chemotherapy for Recurrent Ovarian Cancer
  publication-title: Anti Cancer Drugs
  doi: 10.1097/00001813-199801000-00006
– volume: 151
  year: 2016
  ident: B321
  article-title: Long-Term Effects of Hepatitis B Immunization of Infants in Preventing Liver Cancer
  publication-title: Gastroenterology
  doi: 10.1053/j.gastro.2016.05.048
– volume: 104
  year: 2011
  ident: B99
  article-title: Role of Multidrug Resistance Protein 2 ( MRP2 ) in Chemoresistance and Clinical Outcome in Oesophageal Squamous Cell Carcinoma
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6606071
– volume: 17
  year: 1963
  ident: B51
  article-title: BCR-ABL Point Mutations and TKI Treatment in CML Patients
  publication-title: J Hematol Transfus
  doi: 10.11606/issn.2358-792x.v17i2p111-116
– volume: 10
  year: 2019
  ident: B200
  article-title: Conserved Autophagy Pathway Contributes to Stress Tolerance and Virulence and Differentially Controls Autophagic Flux Upon Nutrient Starvation in Cryptococcus Neoformans
  publication-title: Front Microbiol
  doi: 10.3389/fmicb.2019.02690
– volume: 77
  year: 1997
  ident: B9
  article-title: Expression of MDR1 (Multidrug Resistance) Gene and Its Protein in Normal Human Kidney
  publication-title: Nephron
  doi: 10.1159/000190289
– volume: 16
  year: 2017
  ident: B448
  article-title: Nanoformulation of Olaparib Amplifies PARP Inhibition and Sensitizes PTEN/TP53-Deficient Prostate Cancer to Radiation
  publication-title: Mol Cancer Ther
  doi: 10.1158/1535-7163.MCT-16-0740
– volume: 67
  year: 2007
  ident: B430
  article-title: Modulation of Intracellular Ceramide Using Polymeric Nanoparticles to Overcome Multidrug Resistance in Cancer
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-06-1648
– volume: 9
  year: 2014
  ident: B445
  article-title: Apoptotic Cascade Inspired Lipid Nanovesicles Show Synergism With Encapsulated Paclitaxel in Chemoresistant Colon Carcinoma
  publication-title: Nanomedicine
  doi: 10.2217/nnm.13.182
– volume: 2014
  year: 2014
  ident: B218
  article-title: Blocked Autophagy by miR-101 Enhances Osteosarcoma Cell Chemosensitivity In Vitro
  publication-title: Sci World J
  doi: 10.1155/2014/794756
– volume: 6
  year: 2011
  ident: B253
  article-title: Sensitive and Specific Fluorescent Probes for Functional Analysis of the Three Major Types of Mammalian ABC Transporters
  publication-title: PLos One
  doi: 10.1371/journal.pone.0022429
– volume: 23
  year: 2018
  ident: B468
  article-title: The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2018.04.046
– volume: 1
  start-page: S99
  year: 1996
  ident: B474
  article-title: A Comparative Study of the Risk Factors for Lung Cancer in Guangdong , China
  publication-title: Lung Cancer
  doi: 10.1016/s0169-5002(96)90215-9
– volume: 15
  year: 2012
  ident: B138
  article-title: Immunotherapy: A Useful Strategy to Help Combat Multidrug Resistance
  publication-title: Drug Resist Updates
  doi: 10.1016/j.drup.2012.03.003
– volume: 10
  start-page: 51
  year: 2006
  ident: B202
  article-title: Autophagy Promotes Tumor Cell Survival and Restricts Necrosis, Inflammation, and Tumorigenesis
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2006.06.001
– volume: 10
  year: 2018
  ident: B34
  article-title: Chemoresistance and the Self-Maintaining Tumor Microenvironment
  publication-title: Cancers
  doi: 10.3390/cancers10120471
– volume: 595
  year: 2016
  ident: B3
  article-title: The Role of miRNAs in Drug Resistance and Prognosis of Breast Cancer Formalin-Fixed Paraffin-Embedded Tissues
  publication-title: Gene
  doi: 10.1016/j.gene.2016.10.015
– volume: 364
  year: 2004
  ident: B327
  article-title: Efficacy of a Bivalent L1 Virus-Like Particle Vaccine in Prevention of Infection With Human Papillomavirus Types 16 and 18 in Young Women: A Randomised Controlled Trial
  publication-title: Lancet
  doi: 10.1016/S0140-6736(04)17398-4
– volume: 11
  year: 2014
  ident: B415
  article-title: Liposomal Nitrooxy-Doxorubicin: One Step Over Caelyx in Drug-Resistant Human Cancer Cells
  publication-title: Mol Pharm
  doi: 10.1021/mp500257s
– volume: 2014
  year: 2014
  ident: B477
  article-title: Multidrug Resistance: An Emerging Crisis
  publication-title: Interdiscip Perspect Infect Dis
  doi: 10.1155/2014/541340
– volume: 9
  start-page: 881
  year: 2012
  ident: B227
  article-title: Molecular Mechanism of SAHA on Regulation of Autophagic Cell Death in Tamoxifen-Resistant MCF-7 Breast Cancer Cells
  publication-title: Int J Med Sci
  doi: 10.7150/ijms.5011
– volume: 14
  year: 2013
  ident: B134
  article-title: Serum miR-19a Predicts Resistance to FOLFOX Chemotherapy in Advanced Colorectal Cancer Cases
  publication-title: Asian Pacif J Cancer Prev
  doi: 10.7314/APJCP.2013.14.12.7421
– volume: 124
  year: 2011
  ident: B174
  article-title: A DNA-Dependent Stress Response Involving DNA-PK Occurs in Hypoxic Cells and Contributes to Cellular Adaptation to Hypoxia
  publication-title: J Cell Sci
  doi: 10.1242/jcs.078030
– volume: 47
  year: 1986
  ident: B7
  article-title: Internal Duplication and Homology With Bacterial Transport Proteins in the Mdr1 (P-Glycoprotein) Gene From Multidrug-Resistant Human Cells
  publication-title: Cell
  doi: 10.1016/0092-8674(86)90595-7
– volume: 37
  year: 2019
  ident: B343
  article-title: Tumor-Associated Antigens Identified Early in Mouse Mammary Tumor Development can be Effective Vaccine Targets
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2019.05.024
– volume: 39
  start-page: 1010428317695525
  year: 2017
  ident: B299
  article-title: Beyond Circulating microRNA Biomarkers: Urinary microRNAs in Ovarian and Breast Cancer
  publication-title: Tumor Biol
  doi: 10.1177/1010428317695525
– volume: 15
  year: 2009
  ident: B344
  article-title: The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-09-0737
– volume: 70
  start-page: 7
  year: 2020
  ident: B1
  article-title: Cancer Statistics, 2020
  publication-title: Ca-a Cancer J Clin
  doi: 10.3322/caac.21590
– volume: 6
  start-page: 1
  year: 2016
  ident: B455
  article-title: Overcoming Doxorubicin Resistance of Cancer Cells by Cas9-Mediated Gene Disruption
  publication-title: Sci Rep
  doi: 10.1038/srep22847
– volume: 35
  year: 2014
  ident: B304
  article-title: Exosomes Mediate Drug Resistance Transfer in MCF-7 Breast Cancer Cells and a Probable Mechanism is Delivery of P-Glycoprotein
  publication-title: Tumor Biol
  doi: 10.1007/s13277-014-2377-z
– volume: 7
  year: 2020
  ident: B402
  article-title: Nanoparticle-Based Drug Delivery in Cancer Therapy and Its Role in Overcoming Drug Resistance
  publication-title: Front Mol Biosci
  doi: 10.3389/FMOLB.2020.00193/BIBTEX
– volume: 40
  year: 2017
  ident: B171
  article-title: Cobalt Chloride Induces Expression and Function of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Renal Proximal Tubular Epithelial Cell Line HK-2
  publication-title: Biol Pharm Bull
  doi: 10.1248/bpb.b16-00684
– volume: 35
  start-page: 296
  year: 2017
  ident: B310
  article-title: Exosomal DNMT1 Mediates Cisplatin Resistance in Ovarian Cancer
  publication-title: Cell Biochem Funct
  doi: 10.1002/cbf.3276
– volume: 276
  year: 2001
  ident: B255
  article-title: Characterization of the Catalytic Cycle of ATP Hydrolysis by Human P-Glycoprotein: The Two ATP Hydrolysis Events in a Single Catalytic Cycle are Kinetically Similar But Affect Different Functional Outcomes
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M011294200
– year: 1990
  ident: B381
  article-title: The Role of Calpain in Stimulus-Response Coupling: Evidence That Calpain Mediates Agonist-Induced Expression of Procoagulant Activity in Platelets
  doi: 10.1182/blood.V76.12.2510.2510
– year: 2015
  ident: B40
  article-title: Activation of the BMP-BMPR Pathway Conferred Resistance to EGFR-TKIs in Lung Squamous Cell Carcinoma Patients With EGFR Mutations
  doi: 10.1073/pnas.1510837112
– volume: 24
  year: 2006
  ident: B262
  article-title: Association of High-Level MRP1 Expression With Poor Clinical Outcome in a Large Prospective Study of Primary Neuroblastoma
  publication-title: J Clin Oncol
  doi: 10.1200/JCO.2005.01.6196
– volume: 76
  year: 2016
  ident: B414
  article-title: Photodynamic Therapy Synergizes With Irinotecan to Overcome Compensatory Mechanisms and Improve Treatment Outcomes in Pancreatic Cancer
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-15-0391
– volume: 14
  year: 2018
  ident: B427
  article-title: Fluorescent Nanodiamonds are Efficient, Easy-to-Use Cyto-Compatible Vehicles for Monitored Delivery of non-Coding Regulatory RNAs
  publication-title: J BioMed Nanotechnol
  doi: 10.1166/jbn.2018.2540
– volume: 517
  year: 2015
  ident: B453
  article-title: Genome-Scale Transcriptional Activation by an Engineered CRISPR-Cas9 Complex
  publication-title: Nature
  doi: 10.1038/nature14136
– volume: 146
  year: 2011
  ident: B35
  article-title: Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
  publication-title: Cell
  doi: 10.1016/J.CELL.2011.07.026
– volume: 11
  start-page: 4470
  year: 2019
  ident: B163
  article-title: ENO1 Silencing Impaires Hypoxia-Induced Gemcitabine Chemoresistance Associated With Redox Modulation in Pancreatic Cancer Cells
  publication-title: Am J Transl Res
– volume: 10
  year: 2020
  ident: B21
  article-title: Phytochemicals in Cancer Treatment: From Preclinical Studies to Clinical Practice
  publication-title: Front Pharmacol
  doi: 10.3389/fphar.2019.01614
– volume: 2019
  year: 2019
  ident: B216
  article-title: miR-199a-5p Represses Protective Autophagy and Overcomes Chemoresistance by Directly Targeting DRAM1 in Acute Myeloid Leukemia
  publication-title: J Oncol
  doi: 10.1155/2019/5613417
– volume: 115
  year: 2017
  ident: B305
  article-title: UCH-L1-Containing Exosomes Mediate Chemotherapeutic Resistance Transfer in Breast Cancer
  publication-title: J Surg Oncol
  doi: 10.1002/jso.24614
– volume: 7
  start-page: 1
  year: 2012
  ident: B238
  article-title: Functional Characterization of CLPTM1L as a Lung Cancer Risk Candidate Gene in the 5p15.33 Locus
  publication-title: PLos One
  doi: 10.1371/journal.pone.0036116
– volume: 374
  year: 2009
  ident: B330
  article-title: Efficacy of Human Papillomavirus (HPV)-16/18 AS04-Adjuvanted Vaccine Against Cervical Infection and Precancer Caused by Oncogenic HPV Types (PATRICIA): Final Analysis of a Double-Blind, Randomised Study in Young Women
  publication-title: Lancet
  doi: 10.1016/S0140-6736(09)61248-4
– volume: 106
  start-page: 1
  year: 2016
  ident: B429
  article-title: Electroneutral Composite Polymersomes Self-Assembled by Amphiphilic Polyphosphazenes for Effective miR-200c In Vivo Delivery to Inhibit Drug Resistant Lung Cancer
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2016.08.001
– volume: 356
  year: 2017
  ident: B162
  article-title: New Horizons in Hypoxia Signaling Pathways
  publication-title: Exp Cell Res
  doi: 10.1016/j.yexcr.2017.03.008
– volume: 7
  year: 2017
  ident: B18
  article-title: The Different Mechanisms of Cancer Drug Resistance: A Brief Review
  publication-title: Adv Pharm Bull
  doi: 10.15171/apb.2017.041
– volume: 12
  start-page: 10
  year: 2020
  ident: B164
  article-title: Role of Oxygen and Nitrogen Radicals in the Mechanism of Anticancer Drug Cytotoxicity
  publication-title: J Cancer Sci Ther
– volume: 60
  year: 2000
  ident: B245
  article-title: Extensive Contribution of the Multidrug Transporters P-Glycoprotein and Mrp1 to Basal Drug Resistance
  publication-title: Cancer Res
– volume: 113
  year: 2005
  ident: B277
  article-title: Overexpression and Significance of Prion Protein in Gastric Cancer and Multidrug-Resistant Gastric Carcinoma Cell Line SGC7901/ADR
  publication-title: Int J Cancer
  doi: 10.1002/ijc.20570
– volume: 11
  start-page: 1
  year: 2018
  ident: B471
  article-title: Clinical Analysis of Chemo-Resistance Risk Factors in Endometriosis Associated Ovarian Cancer
  publication-title: J Ovarian Res
  doi: 10.1186/s13048-018-0418-8
– volume: 587
  year: 2013
  ident: B183
  article-title: MicroRNA-106a Induces Multidrug Resistance in Gastric Cancer by Targeting RUNX3
  publication-title: FEBS Lett
  doi: 10.1016/j.febslet.2013.06.058
– volume: 78
  year: 2018
  ident: B458
  article-title: ER Stress Signaling Promotes the Survival of Cancer “Persister Cells” Tolerant to EGFR Tyrosine Kinase Inhibitors
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-17-1904
– volume: 26
  year: 1965
  ident: B135
  article-title: The Effectiveness of Combinations of Antileukemic Agents in Inducing and Maintaining Remission in Children With Acute Leukemia
  publication-title: Blood
  doi: 10.1182/blood.V26.5.642.642
– volume: 4
  year: 2013
  ident: B239
  article-title: Human Pluripotent Stem Cells With Distinct X Inactivation Status Show Molecular and Cellular Differences Controlled by the X-Linked ELK-1 Gene
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2013.06.026
– volume: 81
  year: 1989
  ident: B168
  article-title: Drug Resistance in Chinese Hamster Ovary Cells During Recovery From Severe Hypoxia
  publication-title: JNCI: J Natl Cancer Institute
  doi: 10.1093/jnci/81.16.1235
– volume: 16
  year: 2009
  ident: B50
  article-title: Mechanisms of Primary and Secondary Resistance to Imatinib in Chronic Myeloid Leukemia
  publication-title: Cancer Control
  doi: 10.1177/107327480901600204
– volume: 487
  year: 2012
  ident: B88
  article-title: Tumour Micro-Environment Elicits Innate Resistance to RAF Inhibitors Through HGF Secretion
  publication-title: Nature
  doi: 10.1038/nature11183
– volume: 559
  year: 2015
  ident: B296
  article-title: Cytidine Deaminase Polymorphism Predicts Toxicity of Gemcitabine-Based Chemotherapy
  publication-title: Gene
  doi: 10.1016/j.gene.2015.01.010
– volume: 48
  year: 2016
  ident: B368
  article-title: Immunologic Approaches to Cancer Prevention – Current Status, Challenges and Future Perspectives
  publication-title: Semin Oncol
  doi: 10.1053/j.seminoncol.2015.11.001
– volume: 59
  start-page: 47
  year: 2010
  ident: B356
  article-title: Myeloid-Derived Suppressor Cells in Mammary Tumor Progression in FVB Neu Transgenic Mice
  publication-title: Cancer Immunol Immunother
  doi: 10.1007/s00262-009-0719-2
– volume: 67
  year: 2013
  ident: B416
  article-title: Overcoming Multidrug Resistance Using Liposomal Epirubicin and Antisense Oligonucleotides Targeting Pump and Nonpump Resistances In Vitro and In Vivo
  publication-title: Biomed Pharmacother
  doi: 10.1016/j.biopha.2012.12.002
– volume: 54
  year: 2019
  ident: B224
  article-title: LncRNA MALAT1 Potentiates Autophagy Associated Cisplatin Resistance by Regulating the microRNA 30b/Autophagy Related Gene 5 Axis in Gastric Cancer
  publication-title: Int J Oncol
  doi: 10.3892/ijo.2018.4609
– volume: 8
  year: 2017
  ident: B113
  article-title: Long Non-Coding RNAs in Anti-Cancer Drug Resistance
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.12461
– volume: 21
  year: 2001
  ident: B283
  article-title: In Vitro Chemosensitivity of Human Soft Tissue Sarcoma
  publication-title: Anticancer Res
– volume: 7
  year: 2010
  ident: B443
  article-title: Paclitaxel Nanocrystals for Overcoming Multidrug Resistance in Cancer
  publication-title: Mol Pharm
  doi: 10.1021/mp100012s
– volume: 21
  start-page: 181
  year: 2018
  ident: B29
  article-title: CRISPR/Cas9, a New Approach to Successful Knockdown of ABCB1/P-Glycoprotein and Reversal of Chemosensitivity in Human Epithelial Ovarian Cancer Cell Line
  publication-title: Iran J Basic Med Sci
  doi: 10.22038/IJBMS.2017.25145.6230
– volume: 8
  year: 2009
  ident: B172
  article-title: Hypoxia Prevents Etoposide-Induced DNA Damage in Cancer Cells Through a Mechanism Involving Hypoxia-Inducible Factor 1
  publication-title: Mol Cancer Ther
  doi: 10.1158/1535-7163.MCT-08-1090
– volume: 10
  start-page: 1
  year: 2020
  ident: B301
  article-title: Plasma microRNA Profiles: Identification of miR-1229-3p as a Novel Chemoresistant and Prognostic Biomarker in Gastric Cancer
  publication-title: Sci Rep
  doi: 10.1038/s41598-020-59939-8
– volume: 358
  year: 2008
  ident: B144
  article-title: Oncogenes and Cancer. Supplementary Appendix
  publication-title: N Engl J Med
  doi: 10.1056/NEJMra072367
– volume: 63
  year: 2014
  ident: B357
  article-title: Targeted Depletion of an MDSC Subset Unmasks Pancreatic Ductal Adenocarcinoma to Adaptive Immunity
  publication-title: Gut
  doi: 10.1136/gutjnl-2013-306271
– volume: 2
  start-page: 43
  year: 2009
  ident: B73
  article-title: Methotrexate-Induced Acute Leukemia: Report of Three Cases and Review of the Literature
  publication-title: Clin Med Case Rep
  doi: 10.4137/CCREP.S3078
– volume: 7
  start-page: 893
  year: 2000
  ident: B142
  article-title: Mdr1 Promoter-Driven Tumor Necrosis Factor-α Expression for a Chemotherapy-Controllable Combined In Vivo Gene Therapy and Chemotherapy of Tumors
  publication-title: Cancer Gene Ther
  doi: 10.1038/sj.cgt.7700196
– volume: 12
  start-page: 3
  year: 2018
  ident: B109
  article-title: Emerging Functions of the EGFR in Cancer
  publication-title: Mol Oncol
  doi: 10.1002/1878-0261.12155
– volume: 173
  year: 2017
  ident: B421
  article-title: Photo-Catalytic, Anti-Bacterial, and Anti-Cancer Properties of Phyto-Mediated Synthesis of Silver Nanoparticles From Artemisia Tournefortiana Rchb Extract
  publication-title: J Photochem Photobiol B: Biol
  doi: 10.1016/j.jphotobiol.2017.07.003
– volume: 1226
  start-page: 89
  year: 1994
  ident: B152
  article-title: Oncogene Overexpression and De Novo Drug-Resistance in Human Prostate Cancer Cells
  publication-title: Biochim Biophys Acta
  doi: 10.1016/0925-4439(94)90063-9
– volume: 100
  year: 2009
  ident: B295
  article-title: Homozygous CDA* 3 is a Major Cause of Life-Threatening Toxicities in Gemcitabine-Treated Japanese Cancer Patients
  publication-title: Br J Cancer
  doi: 10.1038/sj.bjc.6604971
– volume: 23
  year: 2017
  ident: B331
  article-title: Dendritic Cell Vaccination Enhances Immune Responses and Induces Regression of HER2pos DCIS Independent of Route: Results of Randomized Selection Design Trial
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-16-1924
– volume: 32
  year: 2011
  ident: B431
  article-title: Synergistic Effect of Folate-Mediated Targeting and Verapamil-Mediated P-Gp Inhibition With Paclitaxel-Polymer Micelles to Overcome Multi-Drug Resistance
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2011.08.041
– volume: 39
  start-page: 1
  year: 2020
  ident: B182
  article-title: Hypoxia Induced Ferritin Light Chain (FTL) Promoted Epithelia Mesenchymal Transition and Chemoresistance of Glioma
  publication-title: J Exp Clin Cancer Res
  doi: 10.1186/s13046-020-01641-8
– volume: 30
  year: 2011
  ident: B140
  article-title: Tumor Necrosis Factor Alpha Induces Stronger Cytotoxicity in ABCG2-Overexpressing Resistant Breast Cancer Cells Compared With Their Drug-Sensitive Parental Line
  publication-title: DNA Cell Biol
  doi: 10.1089/dna.2010.1143
– volume: 155
  year: 2013
  ident: B36
  article-title: Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
  publication-title: Cell
  doi: 10.1016/J.CELL.2013.11.012
– volume: 1
  start-page: 57
  year: 2005
  ident: B320
  article-title: Cancer Immunoprevention
  publication-title: Future Oncol
  doi: 10.1517/14796694.1.1.57
– volume: 55
  year: 2016
  ident: B347
  article-title: Epidermal Growth Factor Receptor Derived Peptide Vaccination to Prevent Lung Adenocarcinoma Formation: An In Vivo Study in a Murine Model of EGFR Mutant Lung Cancer
  publication-title: Mol Carcinog
  doi: 10.1002/mc.22405
– volume: 145
  start-page: 56
  year: 2017
  ident: B412
  article-title: Co-Delivery of Oxygen and Erlotinib by Aptamer-Modified Liposomal Complexes to Reverse Hypoxia-Induced Drug Resistance in Lung Cancer
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2017.08.030
– volume: 141
  start-page: 69
  year: 2010
  ident: B90
  article-title: A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
  publication-title: Cell
  doi: 10.1016/j.cell.2010.02.027
– volume: 91
  start-page: 47
  year: 2019
  ident: B361
  article-title: The Prognosis of Head and Neck Squamous Cell Carcinoma Related to Immunosuppressive Tumor Microenvironment Regulated by IL-6 Signaling
  publication-title: Oral Oncol
  doi: 10.1016/j.oraloncology.2019.02.027
– volume: 7
  start-page: 291
  year: 2015
  ident: B201
  article-title: Targeting Autophagy in Cancer Management–Strategies and Developments
  publication-title: Cancer Manag Res
  doi: 10.2147/CMAR.S34859
– volume: 29
  year: 2010
  ident: B382
  article-title: Calpain Regulates Sensitivity to Trastuzumab and Survival in HER2-Positive Breast Cancer
  publication-title: Oncogene
  doi: 10.1038/onc.2009.422
– volume: 13
  start-page: 89
  year: 2012
  ident: B329
  article-title: Overall Efficacy of HPV-16/18 AS04-Adjuvanted Vaccine Against Grade 3 or Greater Cervical Intraepithelial Neoplasia: 4-Year End-of-Study Analysis of the Randomised, Double-Blind PATRICIA Trial
  publication-title: Lancet Oncol
  doi: 10.1016/S1470-2045(11)70286-8
– volume: 32
  year: 2016
  ident: B75
  article-title: Understanding the Genetic Mechanisms of Cancer Drug Resistance Using Genomic Approaches
  publication-title: Trends Genet
  doi: 10.1016/J.TIG.2015.11.003
– volume: 6
  start-page: 237ra67
  year: 2014
  ident: B359
  article-title: Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy
  publication-title: Sci Transl Med
  doi: 10.1126/scitranslmed.3007974
– volume: 2
  year: 2005
  ident: B388
  article-title: Inhibition of Endothelial Activation: A New Way to Treat Cerebral Malaria
  publication-title: PloS Med
  doi: 10.1371/journal.pmed.0020245
– volume: 36
  start-page: 293
  year: 2017
  ident: B66
  article-title: Extracellular Purines, Purinergic Receptors and Tumor Growth
  publication-title: Oncogene
  doi: 10.1038/onc.2016.206
– volume: 98
  year: 2002
  ident: B287
  article-title: Prediction of Chemotherapeutic Response by Collagen Gel Droplet Embedded Culture-Drug Sensitivity Test in Human Breast Cancers
  publication-title: Int J Cancer
  doi: 10.1002/ijc.10208
– volume: 15
  year: 2016
  ident: B179
  article-title: PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species
  publication-title: Mol Cancer Ther
  doi: 10.1158/1535-7163.MCT-15-1018
– start-page: 299
  volume-title: “Multidrug Resistance Proteins (MRPs, ABCCs): Importance for Pathophysiology and Drug Therapy BT - Drug Transporters.,”
  year: 2011
  ident: B252
– volume: 66
  start-page: 45
  year: 2006
  ident: B282
  article-title: Individualized Cancer Chemotherapy Integrating Drug Sensitivity Tests, Pathological Profile Analysis and Computational Coordination – An Effective Strategy to Improve Clinical Treatment
  publication-title: Med Hypotheses
  doi: 10.1016/j.mehy.2005.07.023
– volume: 268
  start-page: 120537
  year: 2021
  ident: B442
  article-title: Activatable Nanomedicine for Overcoming Hypoxia-Induced Resistance to Chemotherapy and Inhibiting Tumor Growth by Inducing Collaborative Apoptosis and Ferroptosis in Solid Tumors
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2020.120537
– volume: 7
  year: 1996
  ident: B157
  article-title: Staurosporine Resistance Accompanies DNA Tumor Virus-Induced Immortalization and Is Independent of the Expression and Activities of ERK1, ERK2, Cyclin A, Cyclin-Dependent Kinase (Cdk) 2, and Cdk4
  publication-title: Cell Growth Differ: Mol Biol J Am Assoc Cancer Res
– volume: 73
  year: 1994
  ident: B150
  article-title: Prognostic Significance of HER-2/Neu Oncoprotein Expression in Node-Positive Breast Cancer. The Influence of the Pattern of Immunostaining and Adjuvant Therapy
  publication-title: Cancer
  doi: 10.1002/1097-0142(19940501)73:9<2359::aid-cncr2820730919>3.0.co;2-9
– volume: 5
  year: 2011
  ident: B441
  article-title: Controlled Intracellular Release of Doxorubicin in Multidrug-Resistant Cancer Cells by Tuning the Shell-Pore Sizes of Mesoporous Silica Nanoparticles
  publication-title: ACS Nano
  doi: 10.1021/nn2033105
– volume: 33
  year: 2014
  ident: B132
  article-title: miR-508-5p Regulates Multidrug Resistance of Gastric Cancer by Targeting ABCB1 and ZNRD1
  publication-title: Oncogene
  doi: 10.1038/onc.2013.297
– volume: 64
  year: 2012
  ident: B435
  article-title: Triazine Dendrimers as Drug Delivery Systems: From Synthesis to Therapy
  publication-title: Adv Drug Delivery Rev
  doi: 10.1016/j.addr.2012.03.008
– volume: 36
  start-page: 1
  year: 2020
  ident: B214
  article-title: Autophagy-Mediating microRNAs in Cancer Chemoresistance
  publication-title: Cell Biol Toxicol
  doi: 10.1007/s10565-020-09553-1
– volume: 97
  year: 2018
  ident: B226
  article-title: Upregulation of CASC2 Sensitized Glioma to Temozolomide Cytotoxicity Through Autophagy Inhibition by Sponging miR-193a-5p and Regulating mTOR Expression
  publication-title: Biomed Pharmacother
  doi: 10.1016/j.biopha.2017.10.146
– volume: 12
  start-page: 3721
  year: 2017
  ident: B315
  article-title: Cisplatin-Resistant Lung Cancer Cell–Derived Exosomes Increase Cisplatin Resistance of Recipient Cells in Exosomal miR-100–5p-Dependent Manner
  publication-title: Int J Nanomedicine
  doi: 10.2147/IJN.S131516
– volume: 8
  year: 2008
  ident: B290
  article-title: Cancer Stem Cells in Solid Tumours: Accumulating Evidence and Unresolved Questions
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc2499
– volume: 738
  start-page: 83
  year: 2014
  ident: B306
  article-title: Microvesicles Mediate Transfer of P-Glycoprotein to Paclitaxel-Sensitive A2780 Human Ovarian Cancer Cells, Conferring Paclitaxel-Resistance
  publication-title: Eur J Pharmacol
  doi: 10.1016/j.ejphar.2014.05.026
– volume: 2
  year: 2012
  ident: B230
  article-title: Circumventing Cancer Drug Resistance in the Era of Personalized Medicine
  publication-title: Cancer Discovery
  doi: 10.1158/2159-8290.CD-12-0012
– volume: 102
  year: 2005
  ident: B270
  article-title: Induction of Lysosomal Membrane Permeabilization by Compounds That Activate P53-Independent Apoptosis
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0408592102
– volume: 387
  year: 2017
  ident: B450
  article-title: Application of CRISPR-Mediated Genome Engineering in Cancer Research
  publication-title: Cancer Lett
  doi: 10.1016/j.canlet.2016.03.029
– volume: 25
  year: 2013
  ident: B133
  article-title: MiR-27a Modulates the MDR1/P-Glycoprotein Expression by Inhibiting FZD7/β-Catenin Pathway in Hepatocellular Carcinoma Cells
  publication-title: Cell Signall
  doi: 10.1016/j.cellsig.2013.08.032
– volume: 51
  year: 1991
  ident: B10
  article-title: Characterization of the Human MDR3 P-Glycoprotein and Its Recognition by P-Glycoprotein-Specific Monoclonal Antibodies
  publication-title: Cancer Res
– volume: 29
  year: 2016
  ident: B360
  article-title: CXCR2 Inhibition Profoundly Suppresses Metastases and Augments Immunotherapy in Pancreatic Ductal Adenocarcinoma
  publication-title: Cancer Cell
  doi: 10.1016/j.ccell.2016.04.014
– volume: 18
  year: 2013
  ident: B57
  article-title: Contribution of Intracellular ATP to Cisplatin Resistance of Tumor Cells
  publication-title: J Biol Inorganic Chem
  doi: 10.1007/s00775-012-0960-6
– volume: 339
  year: 2013
  ident: B274
  article-title: A Peptide Derived From Phage Display Library Exhibits Anti-Tumor Activity by Targeting GRP78 in Gastric Cancer Multidrug Resistance Cells
  publication-title: Cancer Lett
  doi: 10.1016/j.canlet.2013.06.016
– volume: 12
  year: 2018
  ident: B404
  article-title: Epidermal Growth Factor Receptor-Targeting Peptide Nanoparticles Simultaneously Deliver Gemcitabine and Olaparib to Treat Pancreatic Cancer With Breast Cancer 2 (BRCA2) Mutation
  publication-title: ACS Nano
  doi: 10.1021/acsnano.8b01573
– volume: 21
  year: 2012
  ident: B291
  article-title: Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2012.03.003
– volume: 105
  year: 2008
  ident: B389
  article-title: Protection Against Cerebral Malaria by the Low-Molecular-Weight Thiol Pantethine
  publication-title: Proc Natl Acad Sci
  doi: 10.1073/pnas.0706867105
– volume: 21
  start-page: 1618
  year: 2020
  ident: B424
  article-title: Evaluation of the Genotoxic and Oxidative Damage Potential of Silver Nanoparticles in Human NCM460 and HCT116 Cells
  publication-title: Int J Mol Sci
  doi: 10.3390/ijms21051618
– volume: 120
  year: 1994
  ident: B137
  article-title: Influence of Cytokines Onmdr1 Expression in Human Colon Carcinoma Cell Lines: Increased Cytoxicity of MDR Relevant Drugs
  publication-title: J Cancer Res Clin Oncol
  doi: 10.1007/BF01191800
– volume: 27
  year: 2019
  ident: B198
  article-title: Hypoxia Induces Drug Resistance in Colorectal Cancer Through the HIF-1α/miR-338-5p/IL-6 Feedback Loop
  publication-title: Mol Ther
  doi: 10.1016/j.ymthe.2019.05.017
– volume: 33
  year: 1997
  ident: B286
  article-title: The Usefulness of the ATP Assay With Serum-Free Culture for Chemosensitivity Testing of Gastrointestinal Cancer
  publication-title: Eur J Cancer
  doi: 10.1016/S0959-8049(97)00075-0
– volume: 6
  start-page: 28867
  year: 2015
  ident: B220
  article-title: MiR-21 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Inhibiting Autophagy via the PTEN/Akt Pathway
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.4814
– volume: 18
  year: 2018
  ident: B53
  article-title: Extracellular ATP and P2 Purinergic Signalling in the Tumour Microenvironment
  publication-title: Nat Rev Cancer
  doi: 10.1038/s41568-018-0037-0
– volume: 1
  start-page: 1
  year: 2014
  ident: B390
  article-title: Overcoming Cancer Multidrug Resistance Through Inhibition of Microparticles
  publication-title: GSTF J Adv Med Res (JAMR)
  doi: 10.5176/2345-7201_1.4.32
– volume: 47
  year: 1998
  ident: B365
  article-title: Genetic Immunization Against Neu/Erbb2 Transgenic Breast Cancer
  publication-title: Cancer Immunol Immunother
  doi: 10.1007/s002620050519
– volume: 21
  start-page: 1
  year: 2020
  ident: B463
  article-title: Systematic Functional Identification of Cancer Multi-Drug Resistance Genes
  publication-title: Genome Biol
  doi: 10.1186/s13059-020-1940-8
– volume: 7
  start-page: 1
  year: 2017
  ident: B426
  article-title: Investigation of Copper Cysteamine Nanoparticles as a New Type of Radiosensitiers for Colorectal Carcinoma Treatment
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-09375-y
– volume: 2
  year: 2011
  ident: B250
  article-title: The “Specific” P-Glycoprotein Inhibitor Tariquidar Is Also a Substrate and an Inhibitor for Breast Cancer Resistance Protein (BCRP/Abcg2)
  publication-title: ACS Chem Neurosci
  doi: 10.1021/cn100078a
– volume: 10
  year: 2010
  ident: B47
  article-title: The Evolutionary Dynamics of Cancer Prevention
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc2892
– volume: 6
  start-page: 1
  year: 2016
  ident: B336
  article-title: Antibodies Elicited by the First non-Viral Prophylactic Cancer Vaccine Show Tumor-Specificity and Immunotherapeutic Potential
  publication-title: Sci Rep
  doi: 10.1038/srep31740
– volume: 62
  year: 2002
  ident: B409
  article-title: Antivasculature Effects of Doxorubicin-Containing Liposomes in an Intracranial Rat Brain Tumor Model
  publication-title: Cancer Res
– volume: 10
  year: 2009
  ident: B74
  article-title: The Reversal of Drug-Resistance in Tumors Using a Drug-Carrying Nanoparticular System
  publication-title: Int J Mol Sci
  doi: 10.3390/IJMS10093776
– volume: 12
  year: 2015
  ident: B461
  article-title: Multiplexable, Locus-Specific Targeting of Long RNAs With CRISPR-Display
  publication-title: Nat Methods
  doi: 10.1038/nmeth.3433
– volume: 2
  start-page: 1
  year: 2016
  ident: B470
  article-title: Pancreatic Cancer
  publication-title: Nat Rev Dis Primers
  doi: 10.1038/nrdp.2016.22
– volume: 84
  year: 1987
  ident: B11
  article-title: Expression of a Full-Length cDNA for the Human “Mdr1” Gene Confers Resistance to Colchicine, Doxorubicin, and Vinblastine
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.84.9.3004
– volume: 75
  year: 2015
  ident: B386
  article-title: Rho Kinase Inhibitors Block Melanoma Cell Migration and Inhibit Metastasis
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-14-2156
– volume: 6
  start-page: 265
  year: 2015
  ident: B423
  article-title: Novel Trend in Colon Cancer Therapy Using Silver Nanoparticles Synthesized by Honey Bee
  publication-title: J Nanomed Nanotechnol
  doi: 10.4172/2157-7439.1000265
– volume: 20
  year: 2013
  ident: B17
  article-title: DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology
  publication-title: Chem Biol
  doi: 10.1016/j.chembiol.2013.04.007
– volume: 434
  year: 2013
  ident: B129
  article-title: MicroRNA-19a/B Regulates Multidrug Resistance in Human Gastric Cancer Cells by Targeting PTEN
  publication-title: Biochem Biophys Res Commun
  doi: 10.1016/J.BBRC.2013.04.010
– volume: 12
  year: 2011
  ident: B335
  article-title: Vaccines and Other Immunological Approaches for Cancer Immunoprevention
  publication-title: Curr Drug Targets
  doi: 10.2174/138945011798184146
– volume: 30
  start-page: 445
  year: 1995
  ident: B153
  article-title: The Glut Athione s-Transferase Supergene Family: Regulation of GST and the Contribution of the Lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I
  publication-title: Crit Rev Biochem Mol Biol
  doi: 10.3109/10409239509083491
– volume: 51
  year: 2017
  ident: B308
  article-title: Exosomes Promote Cetuximab Resistance via the PTEN/Akt Pathway in Colon Cancer Cells
  publication-title: Braz J Med Biol Res
  doi: 10.1590/1414-431x20176472
– volume: 24
  year: 2017
  ident: B117
  article-title: The Role of Epigenetics in Cancer Drug Resistance
  publication-title: J Kerman Univ Med Sci
– volume: 34
  year: 2013
  ident: B407
  article-title: Development of Targeting Lonidamine Liposomes That Circumvent Drug-Resistant Cancer by Acting on Mitochondrial Signaling Pathways
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2013.01.055
– start-page: 1
  volume-title: “Multidrug Resistance in Cancer BT - Multi-Drug Resistance in Cancer.,”
  year: 2010
  ident: B121
– volume: 11
  start-page: 1
  year: 2020
  ident: B184
  article-title: The Hif1α/Hif2α-Mir210-3p Network Regulates Glioblastoma Cell Proliferation, Dedifferentiation and Chemoresistance Through EGF Under Hypoxic Conditions
  publication-title: Cell Death Dis
  doi: 10.1038/s41419-020-03150-0
– volume: 9
  start-page: 491
  year: 2013
  ident: B67
  article-title: Purinergic Signalling and Cancer
  publication-title: Purinergic Signall
  doi: 10.1007/s11302-013-9372-5
– volume: 3
  start-page: 1
  year: 2012
  ident: B394
  article-title: Delivery of Chemotherapeutic Drugs in Tumour Cell-Derived Microparticles
  publication-title: Nat Commun
  doi: 10.1038/ncomms2282
– volume: 141
  year: 2017
  ident: B309
  article-title: Exosomes Derived From Mesenchymal non-Small Cell Lung Cancer Cells Promote Chemoresistance
  publication-title: Int J Cancer
  doi: 10.1002/ijc.30752
– volume: 6
  year: 2018
  ident: B401
  article-title: Nanomedicine: Principles, Properties, and Regulatory Issues
  publication-title: Front Chem
  doi: 10.3389/FCHEM.2018.00360
– volume: 107
  start-page: 1
  year: 2015
  ident: B52
  article-title: Exosome-Mediated Transfer of microRNAs Within the Tumor Microenvironment and Neuroblastoma Resistance to Chemotherapy
  publication-title: J Natl Cancer Inst
  doi: 10.1093/jnci/djv135
– volume: 51
  year: 2018
  ident: B457
  article-title: Targeting CD44 by CRISPR-Cas9 in Multi-Drug Resistant Osteosarcoma Cells
  publication-title: Cell Physiol Biochem
  doi: 10.1159/000495714
– volume: 64
  year: 2004
  ident: B375
  article-title: Proinvasive Properties of Ovarian Cancer Ascites-Derived Membrane Vesicles
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-04-1800
– volume: 63
  year: 1991
  ident: B244
  article-title: Multidrug Resistance in Human Cancer
  publication-title: Br J Cancer
  doi: 10.1038/bjc.1991.152
– volume: 3
  year: 2005
  ident: B181
  article-title: Pim Family Kinases Enhance Tumor Growth of Prostate Cancer Cells
  publication-title: Mol Cancer Res
  doi: 10.1158/1541-7786.MCR-05-0007
– volume: 88
  year: 1996
  ident: B155
  article-title: Muise-Helmericks R, Li W, Banerjee D, Bertino JR. Effect of Cyclin Dl Overexpression on Drug Sensitivity in a Human Fibrosarcoma Cell Line
  publication-title: J Natl Cancer Inst
  doi: 10.1093/jnci/88.18.1269
– volume: 35
  year: 2007
  ident: B260
  article-title: Expression of Thirty-Six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines
  publication-title: Drug Metab Disposition
  doi: 10.1124/dmd.107.014902
– volume: 205
  year: 2005
  ident: B231
  article-title: Molecular Mechanisms of Drug Resistance
  publication-title: J Pathol
  doi: 10.1002/path.1706
– volume: 72
  year: 2012
  ident: B59
  article-title: Intracellular ATP Levels Are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-11-1674
– volume: 55
  year: 1995
  ident: B159
  article-title: Estrogen Promotes Chemotherapeutic Drug Resistance by a Mechanism Involving Bcl-2 Proto-Oncogene Expression in Human Breast Cancer Cells
  publication-title: Cancer Res
– volume: 19
  year: 2005
  ident: B392
  article-title: Benidipine Improves Oxidized LDL-Dependent Monocyte and Endothelial Dysfunction in Hypertensive Patients With Type 2 Diabetes Mellitus
  publication-title: J Hum Hypertens
  doi: 10.1038/sj.jhh.1001863
– volume: 4
  year: 2019
  ident: B449
  article-title: Layer-By-Layer Nanoparticles for Novel Delivery of Cisplatin and PARP Inhibitors for Platinum-Based Drug Resistance Therapy in Ovarian Cancer
  publication-title: Bioeng Transl Med
  doi: 10.1002/btm2.10131
– volume: 24
  year: 1997
  ident: B151
  article-title: [Cell Signaling and CDDP Resistance]
  publication-title: Gan To Kagaku Ryoho
– volume: 15
  year: 2015
  ident: B462
  article-title: Applications of the CRISPR–Cas9 System in Cancer Biology
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc3950
– volume: 6
  year: 2017
  ident: B31
  article-title: The Combination of Systemic Chemotherapy and Local Treatment may Improve the Survival of Patients With Unresectable Metastatic Colorectal Cancer
  publication-title: Mol Clin Oncol
  doi: 10.3892/mco.2017.1247
– volume: 9
  year: 2019
  ident: B456
  article-title: Targeting uPAR by CRISPR/Cas9 System Attenuates Cancer Malignancy and Multidrug Resistance
  publication-title: Front Oncol
  doi: 10.3389/fonc.2019.00080
– year: 1979
  ident: B451
  article-title: RNA-Guided Human Genome Engineering via Cas9
  publication-title: Science
  doi: 10.1126/science.1232033
– volume: 34
  year: 2014
  ident: B355
  article-title: Pten Null Prostate Epithelium Promotes Localized Myeloid-Derived Suppressor Cell Expansion and Immune Suppression During Tumor Initiation and Progression
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.00090-14
– volume: 82
  year: 2013
  ident: B275
  article-title: In-Depth Research of Multidrug Resistance Related Cell Surface Glycoproteome in Gastric Cancer
  publication-title: J Proteomics
  doi: 10.1016/j.jprot.2013.02.021
– volume: 6
  start-page: 1
  year: 2013
  ident: B84
  article-title: Bypass Mechanisms of Resistance to Receptor Tyrosine Kinase Inhibition in Lung Cancer
  publication-title: Sci Signaling
  doi: 10.1126/scisignal.2004652
– volume: 128
  start-page: 298
  year: 2017
  ident: B161
  article-title: The VHL Tumor Suppressor Gene: Insights Into Oxygen Sensing and Cancer
  publication-title: Trans Am Clin Climatol Assoc
– volume: 21
  start-page: 38
  year: 2007
  ident: B391
  article-title: Effect of Nifedipine on Adiponectin in Hypertensive Patients With Type 2 Diabetes Mellitus
  publication-title: J Hum Hypertens
  doi: 10.1038/sj.jhh.1002100
– volume: 21
  year: 2014
  ident: B241
  article-title: In Vitro and In Vivo Models for Analysis of Resistance to Anticancer Molecular Therapies
  publication-title: Curr Medicinal Chem
  doi: 10.2174/09298673113209990226
– volume: 12
  start-page: 185
  year: 2020
  ident: B433
  article-title: Intracellular Delivery of Anti-SMC2 Antibodies Against Cancer Stem Cells
  publication-title: Pharmaceutics
  doi: 10.3390/pharmaceutics12020185
– volume: 47
  start-page: 100647
  year: 2019
  ident: B317
  article-title: Extracellular Vesicles as a Novel Source of Biomarkers in Liquid Biopsies for Monitoring Cancer Progression and Drug Resistance
  publication-title: Drug Resist Updates
  doi: 10.1016/j.drup.2019.100647
– volume: 7
  year: 2001
  ident: B64
  article-title: Fanconi Anemia Group C Protein Prevents Apoptosis in Hematopoietic Cells Through Redox Regulation of GSTP1
  publication-title: Nat Med
  doi: 10.1038/89937
– volume: 17
  year: 2017
  ident: B235
  article-title: ABCC3 Genetic Variants are Associated With Postoperative Morphine-Induced Respiratory Depression and Morphine Pharmacokinetics in Children
  publication-title: Pharmacogenomics J
  doi: 10.1038/tpj.2015.98
– volume: 258
  year: 1992
  ident: B78
  article-title: Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line
  publication-title: Science
  doi: 10.1126/science.1360704
– volume: 9
  year: 1989
  ident: B243
  article-title: Expression of a Human Multidrug Resistance cDNA (MDR1) in the Bone Marrow of Transgenic Mice: Resistance to Daunomycin-Induced Leukopenia
  publication-title: Mol Cell Biol
  doi: 10.1128/mcb.9.10.4357
– volume: 6
  year: 2017
  ident: B464
  article-title: KEAP1 Loss Modulates Sensitivity to Kinase Targeted Therapy in Lung Cancer
  publication-title: Elife
  doi: 10.7554/eLife.18970
– volume: 2
  start-page: 11
  year: 1991
  ident: B37
  article-title: Double Minute Chromosomes and Homogeneously Staining Regions in Tumors Taken Directly From Patients Versus in Human Tumor Cell Lines
  publication-title: Anticancer Drugs
  doi: 10.1097/00001813-199102000-00002
– volume: 5
  year: 2014
  ident: B70
  article-title: Membrane Transporters in a Human Genome-Scale Metabolic Knowledgebase and Their Implications for Disease
  publication-title: Front Physiol
  doi: 10.3389/fphys.2014.00091
– volume: 23
  year: 2019
  ident: B209
  article-title: MiRNA-153-3p Promotes Gefitinib-Sensitivity in non-Small Cell Lung Cancer by Inhibiting ATG5 Expression and Autophagy
  publication-title: Eur Rev Med Pharmacol Sci
  doi: 10.26355/eurrev_201903_17391
– start-page: 1
  year: 2018
  ident: B33
  article-title: Outcomes of 219 Chronic Myeloid Leukaemia Patients With Additional Chromosomal Abnormalities and / or Tyrosine Kinase Domain Mutations
  publication-title: Int J Lab Hematol
  doi: 10.1111/ijlh.12928
– volume: 6
  year: 2007
  ident: B266
  article-title: Inhibition of the Mitogen-Activated Protein Kinase Pathway Results in the Down-Regulation of P-Glycoprotein
  publication-title: Mol Cancer Ther
  doi: 10.1158/1535-7163.MCT-07-0148
– volume: 17
  year: 2020
  ident: B6
  article-title: The Role of Long Non-Coding RNAs in Mediating Chemoresistance by Modulating Autophagy in Cancer
  publication-title: RNA Biol
  doi: 10.1080/15476286.2020.1737787
– volume: 14
  year: 2011
  ident: B180
  article-title: The Oncogenic PIM Kinase Family Regulates Drug Resistance Through Multiple Mechanisms
  publication-title: Drug Resist Updates
  doi: 10.1016/j.drup.2011.04.002
– volume: 18
  year: 2012
  ident: B348
  article-title: Myeloma-Specific Multiple Peptides Able to Generate Cytotoxic T Lymphocytes: A Potential Therapeutic Application in Multiple Myeloma and Other Plasma Cell Disorders
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-11-2776
– volume: 3
  year: 2014
  ident: B22
  article-title: Recurrence After Surgery in Patients With NSCLC
  publication-title: Transl Lung Cancer Res
  doi: 10.3978/j.issn.2218-6751.2013.12.05
– volume: 108
  year: 2013
  ident: B127
  article-title: Melatonin-Induced Methylation of the ABCG2/BCRP Promoter as a Novel Mechanism to Overcome Multidrug Resistance in Brain Tumour Stem Cells
  publication-title: Br J Cancer
  doi: 10.1038/bjc.2013.188
– volume: 15
  start-page: 599
  year: 2018
  ident: B215
  article-title: miR 30 Decreases Multidrug Resistance in Human Gastric Cancer Cells by Modulating Cell Autophagy
  publication-title: Exp Ther Med
  doi: 10.3892/etm.2017.5354
– volume: 274
  year: 1999
  ident: B380
  article-title: Inhibition of Calpain Blocks Platelet Secretion, Aggregation, and Spreading
  publication-title: J Biol Chem
  doi: 10.1074/jbc.274.51.36321
– volume: 6
  year: 2004
  ident: B259
  article-title: Predicting Drug Sensitivity and Resistance: Profiling ABC Transporter Genes in Cancer Cells
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2004.06.026
– volume: 41
  start-page: 85
  year: 2018
  ident: B460
  article-title: Implications of FGF19 on Sorafenib-Mediated Nitric Oxide Production in Hepatocellular Carcinoma Cells-a Short Report
  publication-title: Cell Oncol
  doi: 10.1007/s13402-017-0354-4
– volume: 8
  year: 2017
  ident: B54
  article-title: Extracellular ATP , as an Energy and Phosphorylating Molecule , Induces Different Types of Drug Resistances in Cancer Cells Through ATP Internalization and Intracellular ATP Level Increase
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.21231
– volume: 1
  year: 2010
  ident: B281
  article-title: Similarity of Drug Sensitivity Test Results on Human Pulmonary Adenocarcinoma Xenografts Transplanted Under the Subrenal Capsules Between Normal Immunocompetent and Immunodeficient Athymic Mice
  publication-title: Int J Pharm Ther
– volume: 12
  year: 2012
  ident: B203
  article-title: Deconvoluting the Context-Dependent Role for Autophagy in Cancer
  publication-title: Nat Rev Cancer
  doi: 10.1038/nrc3262
– volume: 97
  year: 2006
  ident: B265
  article-title: Estrogen-Mediated Post Transcriptional Down-Regulation of P-Glycoprotein in MDR1-Transduced Human Breast Cancer Cells
  publication-title: Cancer Sci
  doi: 10.1111/j.1349-7006.2006.00300.x
– volume: 14
  year: 2008
  ident: B278
  article-title: Prediction of Broad Spectrum Resistance of Tumors Towards Anticancer Drugs
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-07-4525
– volume: 18
  year: 2012
  ident: B82
  article-title: Identification of a Mutation in the Extracellular Domain of the Epidermal Growth Factor Receptor Conferring Cetuximab Resistance in Colorectal Cancer
  publication-title: Nat Med
  doi: 10.1038/nm.2609
– volume: 61
  year: 2010
  ident: B251
  article-title: Inhibition of Anticancer Drug Efflux Transporter P-Glycoprotein by Rosemary Phytochemicals
  publication-title: Pharmacol Res
  doi: 10.1016/j.phrs.2009.11.010
– volume: 18
  year: 1998
  ident: B377
  article-title: The Amount and Proteolytic Content of Vesicles Shed by Human Cancer Cell Lines Correlates With Their In Vitro Invasiveness
  publication-title: Anticancer Res
– volume: 15
  year: 2015
  ident: B27
  article-title: Targeting Microparticle Biogenesis: A Novel Approach to the Circumvention of Cancer Multidrug Resistance
  publication-title: Curr Cancer Drug Targets
  doi: 10.2174/1568009615666150225121508
– volume: 2015
  year: 2015
  ident: B123
  article-title: Overcoming Multidrug Resistance in Cancer Stem Cells
  publication-title: BioMed Res Int
  doi: 10.1155/2015/635745
– volume: 38
  year: 2020
  ident: B363
  article-title: Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma
  publication-title: J Clin Oncol
  doi: 10.1200/JCO.19.01740
– volume: 74
  year: 1996
  ident: B408
  article-title: An Improved Method of Encapsulation of Doxorubicin in Liposomes: Pharmacological, Toxicological and Therapeutic Evaluation
  publication-title: Br J Cancer
  doi: 10.1038/bjc.1996.313
– volume: 8
  start-page: 1
  year: 2013
  ident: B108
  article-title: The Impact of Androgen Receptor Expression on Breast Cancer Survival: A Retrospective Study and Meta-Analysis
  publication-title: PLos One
  doi: 10.1371/journal.pone.0082650
– volume: 10
  start-page: 1
  year: 2019
  ident: B234
  article-title: CHD1L Contributes to Cisplatin Resistance by Upregulating the ABCB1–NF-κb Axis in Human non-Small-Cell Lung Cancer
  publication-title: Cell Death Dis
  doi: 10.1038/s41419-019-1371-1
– volume: 143
  year: 2014
  ident: B62
  article-title: Structural Diversity of ABC Transporters
  publication-title: J Gen Physiol
  doi: 10.1085/JGP.201411164
– volume: 3
  year: 2012
  ident: B383
  article-title: R (H) Oads to Microvesicles
  publication-title: Small GTPases
  doi: 10.4161/sgtp.20755
– volume: 8
  year: 2017
  ident: B101
  article-title: The FOXM1-ABCC5 Axis Contributes to Paclitaxel Resistance in Nasopharyngeal Carcinoma Cells
  publication-title: Cell Death Dis
  doi: 10.1038/cddis.2017.53
– volume: 19
  start-page: 1
  year: 2019
  ident: B15
  article-title: Tumor-Associated Macrophages Modulate Resistance to Oxaliplatin via Inducing Autophagy in Hepatocellular Carcinoma
  publication-title: Cancer Cell Int
  doi: 10.1186/s12935-019-0771-8
– volume: 7
  year: 2008
  ident: B273
  article-title: High Throughput Screening of a Small Molecule One-Bead-One-Compound Combinatorial Library to Identify Attenuators of P21 as Chemotherapy Sensitizers
  publication-title: Cancer Biol Ther
  doi: 10.4161/cbt.7.12.7069
– volume: 1865
  year: 2016
  ident: B136
  article-title: Cytokines in Cancer Drug Resistance: Cues to New Therapeutic Strategies
  publication-title: Biochim Biophys Acta (BBA) - Rev Cancer
  doi: 10.1016/J.BBCAN.2016.03.005
– volume: 31
  start-page: H1
  year: 2013
  ident: B325
  article-title: Comprehensive Control of Human Papillomavirus Infections and Related Diseases
  publication-title: Vaccine
  doi: 10.1016/j.vaccine.2013.10.003
– volume: 32
  year: 2015
  ident: B115
  article-title: The Effect of miR-372 on Genome Instability in MKN-45 Cell Line
  publication-title: J Isfahan Med School
– volume: 40
  year: 2018
  ident: B312
  article-title: Tumor Released lncRNA H19 Promotes Gefitinib Resistance via Packaging Into Exosomes in non Small Cell Lung Cancer
  publication-title: Oncol Rep
  doi: 10.3892/or.2018.6762
– volume: 27
  year: 1998
  ident: B143
  article-title: The Role of Oncogenes in Drug Resistance
  publication-title: Cytotechnology
  doi: 10.1007/978-94-017-2374-9_19
– volume: 72
  year: 2012
  ident: B358
  article-title: Monocytic CCR2+ Myeloid-Derived Suppressor Cells Promote Immune Escape by Limiting Activated CD8 T-Cell Infiltration Into the Tumor Microenvironment
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-11-1792
– volume: 37
  start-page: 1
  year: 2018
  ident: B311
  article-title: Exosome-Mediated Transfer of lncRNA PART1 Induces Gefitinib Resistance in Esophageal Squamous Cell Carcinoma via Functioning as a Competing Endogenous RNA
  publication-title: J Exp Clin Cancer Res
  doi: 10.1186/s13046-018-0845-9
– volume: 1
  year: 2020
  ident: B232
  article-title: Integrative Genomic Analyses Reveal Mechanisms of Glucocorticoid Resistance in Acute Lymphoblastic Leukemia
  publication-title: Nat Cancer
  doi: 10.1038/s43018-020-0037-3
– volume: 19
  start-page: 1
  year: 2019
  ident: B221
  article-title: LncRNA SNHG6 Promotes Chemoresistance Through ULK1-Induced Autophagy by Sponging miR-26a-5p in Colorectal Cancer Cells
  publication-title: Cancer Cell Int
  doi: 10.1186/s12935-019-0951-6
– volume: 54
  year: 2019
  ident: B222
  article-title: LncRNA BLACAT1 is Involved in Chemoresistance of non Small Cell Lung Cancer Cells by Regulating Autophagy
  publication-title: Int J Oncol
  doi: 10.3892/ijo.2018.4614
– volume: 22
  year: 2009
  ident: B475
  article-title: Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors
  publication-title: Clinics Colon Rectal Surg
  doi: 10.1055/s-0029-1242458
– volume: 11
  year: 2007
  ident: B472
  article-title: Epithelial Ovarian Cancer. Risk Factors, Screening and the Role of Prophylactic Oophorectomy
  publication-title: Hippokratia
– volume: 24
  year: 2019
  ident: B14
  article-title: Autophagy Inhibition With Chloroquine Reverts Paclitaxel Resistance and Attenuates Metastatic Potential in Human Nonsmall Lung Adenocarcinoma A549 Cells via ROS Mediated Modulation of β-Catenin Pathway
  publication-title: Apoptosis
  doi: 10.1007/s10495-019-01526-y
– volume: 6
  start-page: 1
  year: 2016
  ident: B43
  article-title: Cisplatin Resistance in Gastric Cancer Cells Is Associated With HER2 Upregulation-Induced Epithelial-Mesenchymal Transition
  publication-title: Sci Rep
  doi: 10.1038/srep20502
– volume: 53
  year: 2018
  ident: B314
  article-title: Exosome-Mediated Transfer of lncRNA SNHG14 Promotes Trastuzumab Chemoresistance in Breast Cancer
  publication-title: Int J Oncol
  doi: 10.3892/ijo.2018.4467
– volume: 8
  year: 2013
  ident: B205
  article-title: Coordinate Autophagy and mTOR Pathway Inhibition Enhances Cell Death in Melanoma
  publication-title: PLos One
  doi: 10.1371/journal.pone.0055096
– volume: 29
  year: 2015
  ident: B349
  article-title: A Multiepitope of XBP1, CD138 and CS1 Peptides Induces Myeloma-Specific Cytotoxic T Lymphocytes in T Cells of Smoldering Myeloma Patients
  publication-title: Leukemia
  doi: 10.1038/leu.2014.159
– volume: 7
  year: 2014
  ident: B25
  article-title: Cancer Immunoprevention: A New Approach to Intercept Cancer Early
  publication-title: Cancer Prev Res
  doi: 10.1158/1940-6207.CAPR-14-0213
– volume: 5
  year: 2014
  ident: B28
  article-title: Nanodrug Delivery in Reversing Multidrug Resistance in Cancer Cells
  publication-title: Front Pharmacol
  doi: 10.3389/fphar.2014.00159
– volume: 42
  year: 2017
  ident: B367
  article-title: Cancer Immunotherapy, Part 3 : Challenges and Future Trends
  publication-title: Pharm Therap
– volume: 8
  year: 2013
  ident: B371
  article-title: Breast Cancer-Derived Microparticles Display Tissue Selectivity in the Transfer of Resistance Proteins to Cells
  publication-title: PLos One
  doi: 10.1371/journal.pone.0061515
– volume: 501
  year: 2013
  ident: B48
  article-title: Influence of Tumour Micro-Environment Heterogeneity on Therapeutic Response
  publication-title: Nature
  doi: 10.1038/nature12626
– volume: 154
  year: 2011
  ident: B24
  article-title: Early UK Experience in the Use of Clofarabine in the Treatment of Relapsed and Refractory Paediatric Acute Lymphoblastic Leukaemia
  publication-title: Br J Haematol
  doi: 10.1111/j.1365-2141.2011.08752.x
– volume: 116
  year: 2006
  ident: B83
  article-title: Allelic Dilution Obscures Detection of a Biologically Significant Resistance Mutation in EGFR-Amplified Lung Cancer
  publication-title: J Clin Invest
  doi: 10.1172/JCI28656
– volume: 284
  year: 2009
  ident: B272
  article-title: Identification of GAS1 as an Epirubicin Resistance-Related Gene in Human Gastric Cancer Cells With a Partially Randomized Small Interfering RNA Library*
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M109.028068
– volume: 53
  year: 2018
  ident: B187
  article-title: Hypoxia-Induced Autophagy Promotes Gemcitabine Resistance in Human Bladder Cancer Cells Through Hypoxia-Inducible Factor 1α Activation
  publication-title: Int J Oncol
  doi: 10.3892/ijo.2018.4376
– volume: 9
  year: 2017
  ident: B467
  article-title: Synergistic Action of the MCL-1 Inhibitor S63845 With Current Therapies in Preclinical Models of Triple-Negative and HER2-Amplified Breast Cancer
  publication-title: Sci Transl Med
  doi: 10.1126/scitranslmed.aam7049
– volume: 30
  year: 1992
  ident: B154
  article-title: Relationship Between Drug Resistance and Oncogenes in Lung Cancer Cell Lines
  publication-title: Nihon Kyobu Shikkan Gakkai zasshi
– volume: 3
  start-page: 267
  year: 2019
  ident: B420
  article-title: Gold Nanoparticles Sensitize Pancreatic Cancer Cells to Gemcitabine
  publication-title: Cell Stress
  doi: 10.15698/cst2019.08.195
– volume: 58
  year: 2019
  ident: B302
  article-title: lncRNA CCAT1 is a Biomarker for the Proliferation and Drug Resistance of Esophageal Cancer via the miR-143/PLK1/BUBR1 Axis
  publication-title: Mol Carcinog
  doi: 10.1002/mc.23109
– volume: 84
  start-page: 6
  year: 1999
  ident: B379
  article-title: Expression of Calpain I Messenger RNA in Human Renal Cell Carcinoma: Correlation With Lymph Node Metastasis and Histological Type
  publication-title: Int J Cancer
  doi: 10.1002/(SICI)1097-0215(19990219)84:1<6::AID-IJC2>3.0.CO;2-T
– volume: 55
  year: 1995
  ident: B156
  article-title: Abnormal Patterns of D-Type Cyclin Expression and G1 Regulation in Human Head and Neck Cancer
  publication-title: Cancer Res
– volume: 53
  year: 2002
  ident: B39
  article-title: Mechanisms of Cancer Drug Resistance
  publication-title: Annu Rev Med
  doi: 10.1146/annurev.med.53.082901.103929
– volume: 24
  year: 2005
  ident: B170
  article-title: Involvement of Hypoxia-Inducible Factor-1-Alpha in Multidrug Resistance Induced by Hypoxia in HepG2 Cells
  publication-title: J Exp Clin Cancer Res: CR
– volume: 6
  start-page: 1
  year: 2008
  ident: B396
  article-title: Clinical and Immunological Evaluation of Anti-Apoptosis Protein, Survivin-Derived Peptide Vaccine in Phase I Clinical Study for Patients With Advanced or Recurrent Breast Cancer
  publication-title: J Transl Med
  doi: 10.1186/1479-5876-6-24
– volume: 9
  year: 1995
  ident: B158
  article-title: BCL-2: Prevention of Apoptosis as a Mechanism of Drug Resistance
  publication-title: Hematol Oncol Clin North Am
  doi: 10.1016/S0889-8588(18)30104-7
– volume: 71
  year: 2002
  ident: B256
  article-title: Mammalian ABC Transporters in Health and Disease
  publication-title: Annu Rev Biochem
  doi: 10.1146/annurev.biochem.71.102301.093055
– volume: 6
  year: 2014
  ident: B116
  article-title: Drug Resistance in Cancer: An Overview
  publication-title: Cancers (Basel)
  doi: 10.3390/cancers6031769
– volume: 4
  year: 2014
  ident: B374
  article-title: Microparticles Mediate the Intercellular Regulation of microRNA-503 and Proline-Rich Tyrosine Kinase 2 to Alter the Migration and Invasion Capacity of Breast Cancer Cells
  publication-title: Front Oncol
  doi: 10.3389/fonc.2014.00220
– volume: 6
  year: 2015
  ident: B197
  article-title: Concepts and Mechanisms Underlying Chemotherapy Induced Immunogenic Cell Death: Impact on Clinical Studies and
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.6113
– volume: 6
  start-page: 201
  year: 2021
  ident: B19
  article-title: Small Molecules in Targeted Cancer Therapy: Advances, Challenges, and Future Perspectives
  publication-title: Signal Transduct Target Ther
  doi: 10.1038/s41392-021-00572-w
– volume: 13
  year: 2017
  ident: B219
  article-title: Expression, Regulation and Function of miR-495 in Healthy and Tumor Tissues
  publication-title: Oncol Lett
  doi: 10.3892/ol.2017.5727
– volume: 5
  year: 2011
  ident: B417
  article-title: Doxorubicin-Tethered Responsive Gold Nanoparticles Facilitate Intracellular Drug Delivery for Overcoming Multidrug Resistance in Cancer Cells
  publication-title: ACS Nano
  doi: 10.1021/nn200007z
– volume: 32
  start-page: 167
  year: 2014
  ident: B395
  article-title: An Approach to Chemotherapy-Associated Toxicity
  publication-title: Emergency Med Clinics
  doi: 10.1016/j.emc.2013.09.002
– volume: 60
  year: 2012
  ident: B399
  article-title: A Multifunctional Mesothelin Antibody-Tagged Microparticle Targets Human Mesotheliomas
  publication-title: J Histochem Cytochem
  doi: 10.1369/0022155412452567
– volume: 215
  year: 2019
  ident: B5
  article-title: Effects of Long Noncoding RNA (Linc-VLDLR) Existing in Extracellular Vesicles on the Occurrence and Multidrug Resistance of Esophageal Cancer Cells
  publication-title: Pathol Res Pract
  doi: 10.1016/j.prp.2018.12.033
– volume: 74
  year: 2014
  ident: B126
  article-title: CD133+ Cancer Stem-Like Cells in Small Cell Lung Cancer Are Highly Tumorigenic and Chemoresistant But Sensitive to a Novel Neuropeptide Antagonist
  publication-title: Cancer Res
  doi: 10.1158/0008-5472.CAN-13-1541
– ident: B236
– volume: 8
  start-page: 674
  year: 2019
  ident: B204
  article-title: A Comprehensive Review of Autophagy and its Various Roles in Infectious, non-Infectious, and Lifestyle Diseases: Current Knowledge and Prospects for Disease Prevention, Novel Drug Design, and Therapy
  publication-title: Cells
  doi: 10.3390/cells8070674
– volume: 86
  year: 2001
  ident: B76
  article-title: Current Understanding of Methotrexate Pharmacology and Efficacy in Acute Leukemias. Use of Newer Antifolates in Clinical Trials
  publication-title: Haematologica
– volume: 60
  year: 1987
  ident: B119
  article-title: Multidrug Resistance in Ovarian Cancer
  publication-title: Cancer
  doi: 10.1002/1097-0142(19901015)60:8+<2075::AID-CNCR2820601521>3.0.CO;2-F
– volume: 9
  start-page: 62
  year: 2017
  ident: B339
  article-title: Local Immune Responsiveness of Mice Bearing Premalignant Oral Lesions to PD-1 Antibody Treatment
  publication-title: Cancers (Basel)
  doi: 10.3390/cancers9060062
– volume: 10
  year: 2017
  ident: B362
  article-title: PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions
  publication-title: Cancer Prev Res
  doi: 10.1158/1940-6207.CAPR-17-0108
– volume: 18
  year: 2012
  ident: B385
  article-title: AT13148 is a Novel, Oral Multi-AGC Kinase Inhibitor With Potent Pharmacodynamic and Antitumor Activity
  publication-title: Clin Cancer Res
  doi: 10.1158/1078-0432.CCR-11-3313
– volume: 47
  year: 2018
  ident: B297
  article-title: SLCO1B1 Polymorphism is a Drug Response Predictive Marker for Advanced Pancreatic Cancer Patients Treated With Gemcitabine, S-1, or Gemcitabine Plus S-1
  publication-title: Pancreas
  doi: 10.1097/MPA.0000000000001052
– volume: 13
  year: 2019
  ident: B237
  article-title: Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment
  publication-title: Stem Cell Rep
  doi: 10.1016/j.stemcr.2019.05.005
– volume: 8
  start-page: 52156
  year: 2017
  ident: B210
  article-title: Lower Beclin 1 Downregulates HER2 Expression to Enhance Tamoxifen Sensitivity and Predicts a Favorable Outcome for ER Positive Breast Cancer
  publication-title: Oncotarget
  doi: 10.18632/oncotarget.11044
– volume: 29
  year: 2008
  ident: B173
  article-title: Impaired DNA Double-Strand Break Repair Contributes to Chemoresistance in HIF-1α-Deficient Mouse Embryonic Fibroblasts
  publication-title: Carcinogenesis
  doi: 10.1093/carcin/bgn231
– volume: 59
  year: 1999
  ident: B190
  article-title: A Senescence-Like Phenotype Distinguishes Tumor Cells That Undergo Terminal Proliferation Arrest After Exposure to Anticancer Agents
  publication-title: Cancer Res
– volume: 128
  year: 2016
  ident: B212
  article-title: Atg7 Suppression Enhances Chemotherapeutic Agent Sensitivity and Overcomes Stroma-Mediated Chemoresistance in Acute Myeloid Leukemia
  publication-title: Blood J Am Soc Hematol
  doi: 10.1182/blood-2016-01-692244
– volume: 18
  start-page: 1533033819828709
  year: 2019
  ident: B300
  article-title: Plasma microRNAs Predict Chemoresistance in Patients With Metastatic Breast Cancer
  publication-title: Technol Cancer Res Treat
  doi: 10.1177/1533033819828709
– volume: 95
  year: 1998
  ident: B79
  article-title: A Multidrug Resistance Transporter From Human MCF-7 Breast Cancer Cells
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.95.26.15665
– volume: 132
  year: 1946
  ident: B2
  article-title: Use of Methyl-Bis(Beta-Chloroethyl)amine Hydrochloride and Tris(Beta-Chloroethyl)amine Hydrochloride for Hodgkin’s Disease, Lymphosarcoma, Leukemia and Certain Allied and Miscellaneous Disorders
  publication-title: J Am Med Assoc
  doi: 10.1001/jama.1946.02870380008004
– volume: 11
  year: 2014
  ident: B439
  article-title: Multifunctional Nanoparticles as Nanocarrier for Vincristine Sulfate Delivery to Overcome Tumor Multidrug Resistance
  publication-title: Mol Pharm
  doi: 10.1021/mp400547u
– volume: 84
  start-page: 1
  year: 2013
  ident: B436
  article-title: Injectable Nanomaterials for Drug Delivery: Carriers, Targeting Moieties, and Therapeutics
  publication-title: Eur J Pharm Biopharm
  doi: 10.1016/j.ejpb.2012.12.009
– volume: 6
  year: 2017
  ident: B326
  article-title: Human Papillomavirus Vaccination: The Population Impact
  publication-title: F1000Res
  doi: 10.12688/f1000research.10691.1
– volume: 19
  year: 2017
  ident: B298
  article-title: Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2017.05.014
– volume: 147
  year: 2011
  ident: B199
  article-title: Autophagy: Renovation of Cells and Tissues
  publication-title: Cell
  doi: 10.1016/J.CELL.2011.10.026
SSID ssj0000650103
Score 2.6859295
SecondaryResourceType review_article
Snippet Cancer is one of the leading causes of death worldwide. Several treatments are available for cancer treatment, but many treatment methods are ineffective...
SourceID doaj
pubmedcentral
proquest
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Enrichment Source
Index Database
StartPage 891652
SubjectTerms cancer
immuno-prevention
intracellular and extracellular ATP
microRNA
multidrug resistance
Oncology
Title Multidrug Resistance in Cancer: Understanding Molecular Mechanisms, Immunoprevention and Therapeutic Approaches
URI https://www.proquest.com/docview/2688087162
https://pubmed.ncbi.nlm.nih.gov/PMC9262248
https://doaj.org/article/f892769914c74af7be4f6c343383b46a
Volume 12
WOSCitedRecordID wos000827820300001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVAON
  databaseName: DOAJ Directory of Open Access Journals
  customDbUrl:
  eissn: 2234-943X
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000650103
  issn: 2234-943X
  databaseCode: DOA
  dateStart: 20110101
  isFulltext: true
  titleUrlDefault: https://www.doaj.org/
  providerName: Directory of Open Access Journals
– providerCode: PRVHPJ
  databaseName: ROAD: Directory of Open Access Scholarly Resources
  customDbUrl:
  eissn: 2234-943X
  dateEnd: 99991231
  omitProxy: false
  ssIdentifier: ssj0000650103
  issn: 2234-943X
  databaseCode: M~E
  dateStart: 20110101
  isFulltext: true
  titleUrlDefault: https://road.issn.org
  providerName: ISSN International Centre
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1NT9wwELUKqiouqB8gtrTIlXpBIt3E3-mNIlB7WFQhkPZm2Y4NK0G22uxy5Ld3JsnSzaW99BJFiRM7fo79RuN5Q8hnHnkVpFGZ9DrPhJQq80l6AKSIkkeDHsM22YS-vDTTaflzI9UX7gnr5IG7jhsnUzKtgMWIoIVL2keRVOACTSsvVEuNgPVsGFPdHCwxgUHnl4Si5TjNa1QsZOyLAUYk2WAdauX6BxxzuENyY8m5eE12e65IT7s2viEvYv2WvJr03vB3ZN5Gz1aL1S29ig0SQUCQzmp6hieLr_RmM3KFTtaZcOkkYrzvrHloTugPDBDBVCj9xkcKpen1n6gsetqrjsdmj9xcnF-ffc_6BApZAJ6xzLwMDpZo50ziFY86FImzyLxTHOwoURVFEAL4UV6aQkXNqyJ3ykQunSpDAqz2yXY9r-MBhnbH5MsKpwB4Ye5Lp30ZdA5V-GB8GpHxujtt6NXFMcnFvQUrAwGwCIBFAGwHwIgcPz_xq1PW-EvZb4jQcznUxG4vwEix_Uix_xopI_Jpja-FfwgdI66O81VjmYJZDC1HqEgPgB_UOLxTz-5aNW4UXGTCvP8fTTwkO_jVuBWN8Q9ke7lYxY_kZXhczprFEdnSU3PUDnQ4Tp7OfwOdbwXA
linkProvider Directory of Open Access Journals
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Multidrug+Resistance+in+Cancer%3A+Understanding+Molecular+Mechanisms%2C+Immunoprevention+and+Therapeutic+Approaches&rft.jtitle=Frontiers+in+oncology&rft.au=Emran%2C+Talha+Bin&rft.au=Shahriar%2C+Asif&rft.au=Mahmud%2C+Aar+Rafi&rft.au=Rahman%2C+Tanjilur&rft.date=2022-06-23&rft.issn=2234-943X&rft.eissn=2234-943X&rft.volume=12&rft.spage=891652&rft_id=info:doi/10.3389%2Ffonc.2022.891652&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2234-943X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2234-943X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2234-943X&client=summon