G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

Estimates vary regarding the number of G protein-coupled receptors (GPCRs), the largest family of membrane receptors that are targeted by approved drugs, and the number of such drugs that target GPCRs. We review current knowledge regarding GPCRs as drug targets by integrating data from public databa...

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Vydané v:	Molecular pharmacology Ročník 93; číslo 4; s. 251
Hlavní autori:	Sriram, Krishna, Insel, Paul A
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.04.2018
Predmet:	Animals Databases, Factual - trends Drug Delivery Systems - methods Drug Delivery Systems - trends Humans Pharmaceutical Preparations - administration & dosage Pharmaceutical Preparations - metabolism Receptors, G-Protein-Coupled - metabolism
ISSN:	1521-0111, 1521-0111
On-line prístup:	Zistit podrobnosti o prístupe
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