Direct Reprogramming of Human Dermal Fibroblasts Into Endothelial Cells Using ER71/ETV2

Direct conversion or reprogramming of human postnatal cells into endothelial cells (ECs), bypassing stem or progenitor cell status, is crucial for regenerative medicine, cell therapy, and pathophysiological investigation but has remained largely unexplored. We sought to directly reprogram human post...

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Bibliographic Details
Published in:	Circulation research Vol. 120; no. 5; p. 848
Main Authors:	Lee, Sangho, Park, Changwon, Han, Ji Woong, Kim, Ju Young, Cho, Kyuwon, Kim, Eun Jae, Kim, Sangsung, Lee, Shin-Jeong, Oh, Se Yeong, Tanaka, Yoshiaki, Park, In-Hyun, An, Hyo Jae, Shin, Claire Min, Sharma, Shraya, Yoon, Young-Sup
Format:	Journal Article
Language:	English
Published:	United States 03.03.2017
Subjects:	Animals Cell Differentiation - physiology Cells, Cultured Cellular Reprogramming Techniques - methods Endothelial Cells - physiology Fibroblasts - physiology Hindlimb - blood supply Hindlimb - physiology Human Umbilical Vein Endothelial Cells Humans Ischemia - metabolism Male Mice Mice, Nude Neovascularization, Physiologic - physiology Transcription Factors - biosynthesis Transcription Factors - genetics endothelial cells fibroblasts cell therapy regenerative medicine ischemia
ISSN:	1524-4571, 1524-4571
Online Access:	Get more information
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