Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease: the ALL-HEART RCT and economic evaluation

Allopurinol is a xanthine oxidase inhibitor that lowers serum uric acid and is used to prevent acute gout flares in patients with gout. Observational and small interventional studies have suggested beneficial cardiovascular effects of allopurinol. To determine whether allopurinol improves major card...

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Vydané v:	Health technology assessment (Winchester, England) Ročník 28; číslo 18; s. 1 - 55
Hlavní autori:	Mackenzie, Isla S, Hawkey, Christopher J, Ford, Ian, Greenlaw, Nicola, Pigazzani, Filippo, Rogers, Amy, Struthers, Allan D, Begg, Alan G, Wei, Li, Avery, Anthony J, Taggar, Jaspal S, Walker, Andrew, Duce, Suzanne L, Barr, Rebecca J, Dumbleton, Jennifer S, Rooke, Evelien D, Townend, Jonathan N, Ritchie, Lewis D, MacDonald, Thomas M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England NIHR Journals Library 01.03.2024
Predmet:	allopurinol cardiovascular system cause of death cost-benefit analysis gout humans multicentre studies myocardial infarction myocardial ischaemia prospective studies randomised controlled trials stroke united kingdom xanthine oxidase MULTICENTRE STUDIES GOUT HUMANS CARDIOVASCULAR SYSTEM ALLOPURINOL STROKE MYOCARDIAL ISCHAEMIA PROSPECTIVE STUDIES CAUSE OF DEATH RANDOMISED CONTROLLED TRIALS XANTHINE OXIDASE MYOCARDIAL INFARCTION UNITED KINGDOM COST-BENEFIT ANALYSIS
ISSN:	2046-4924, 1366-5278, 2046-4924
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