Allopurinol and cardiovascular outcomes in patients with ischaemic heart disease: the ALL-HEART RCT and economic evaluation

Allopurinol is a xanthine oxidase inhibitor that lowers serum uric acid and is used to prevent acute gout flares in patients with gout. Observational and small interventional studies have suggested beneficial cardiovascular effects of allopurinol. To determine whether allopurinol improves major card...

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Bibliographic Details
Published in:	Health technology assessment (Winchester, England) Vol. 28; no. 18; pp. 1 - 55
Main Authors:	Mackenzie, Isla S, Hawkey, Christopher J, Ford, Ian, Greenlaw, Nicola, Pigazzani, Filippo, Rogers, Amy, Struthers, Allan D, Begg, Alan G, Wei, Li, Avery, Anthony J, Taggar, Jaspal S, Walker, Andrew, Duce, Suzanne L, Barr, Rebecca J, Dumbleton, Jennifer S, Rooke, Evelien D, Townend, Jonathan N, Ritchie, Lewis D, MacDonald, Thomas M
Format:	Journal Article
Language:	English
Published:	England NIHR Journals Library 01.03.2024
Subjects:	allopurinol cardiovascular system cause of death cost-benefit analysis gout humans multicentre studies myocardial infarction myocardial ischaemia prospective studies randomised controlled trials stroke united kingdom xanthine oxidase MULTICENTRE STUDIES GOUT HUMANS CARDIOVASCULAR SYSTEM ALLOPURINOL STROKE MYOCARDIAL ISCHAEMIA PROSPECTIVE STUDIES CAUSE OF DEATH RANDOMISED CONTROLLED TRIALS XANTHINE OXIDASE MYOCARDIAL INFARCTION UNITED KINGDOM COST-BENEFIT ANALYSIS
ISSN:	2046-4924, 1366-5278, 2046-4924
Online Access:	Get full text
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