Modelling of immunosensor response: the evaluation of binding kinetics between an immobilized receptor and structurally-different genetically engineered ligands

[Display omitted] •Binding kinetics between immobilized receptor and several genetically engineered ligands (GELs) was evaluated.•GELs were differing by molecular mass and/or by the number of binding sites available for the binding of receptor.•GCSF-Receptor, which binds glycoprotein granulocyte col...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Jg. 297; S. 126770
Hauptverfasser:	Balevicius, Zigmas, Talbot, Julian, Tamosaitis, Linas, Plikusiene, Ieva, Stirke, Arunas, Mickiene, Gitana, Balevicius, Saulius, Paulauskas, Andrius, Ramanavicius, Arunas
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Lausanne Elsevier B.V 15.10.2019 Elsevier Science Ltd Elsevier
Schlagworte:	Antibodies Binding sites Chemical Sciences Diffusion coefficient Ellipsometry Genetic engineering Glycoproteins Gold Granulocyte colony stimulating factor (GCSF) Immunosensor Immunosensors Kinetics Langmuir kinetics model Ligands Proteins Receptor-ligand interaction Receptors Regeneration Spectroscopic ellipsometry Stem cells Three-stage kinetics model Total internal reflection ellipsometry Granulocyte colony stimulating factor (GCSF) Spectroscopic ellipsometry Three-stage kinetics model Receptor-ligand interaction Immunosensor Total internal reflection ellipsometry Langmuir kinetics model granulocyte colony stimulating factor (GCSF) total internal reflection ellipsometry spectroscopic ellipsometry immunosensor receptor-ligand interaction three-stage kinetics model
ISSN:	0925-4005, 1873-3077
Online-Zugang:	Volltext
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