Int&in: A machine learning‐based web server for active split site identification in inteins

Inteins are proteins that excise themselves out of host proteins and ligate the flanking polypeptides in an auto‐catalytic process called protein splicing. In nature, inteins are either contiguous or split. In the case of split inteins, the two fragments must first form a complex for the splicing to...

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Bibliographic Details
Published in:	Protein science Vol. 33; no. 6; pp. e4985 - n/a
Main Authors:	Schmitz, Mirko, Ballestin, Jara Ballestin, Liang, Junsheng, Tomas, Franziska, Freist, Leon, Voigt, Karsten, Di Ventura, Barbara, Öztürk, Mehmet Ali
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01.06.2024 Wiley Subscription Services, Inc
Subjects:	Aes Catalytic Domain CL intein Conserved sequence Fragments Glycoprotein gp41 gp41‐1 Inteins Internet Learning algorithms Machine Learning Npu DnaE Polypeptides protein engineering Protein interaction Protein Splicing Proteins Regression models Servers Software split inteins split site prediction Tools for Protein Science protein engineering CL intein split site prediction Npu DnaE machine learning Aes gp41‐1 split inteins
ISSN:	0961-8368, 1469-896X, 1469-896X
Online Access:	Get full text
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