Beyond 1000 nm Emission Wavelength: Recent Advances in Organic and Inorganic Emitters for Deep‐Tissue Molecular Imaging

In vivo second near‐infrared (NIR‐II, 1.0–1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scatt...

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Published in:Advanced healthcare materials Vol. 8; no. 14; pp. e1900260 - n/a
Main Authors: Ding, Feng, Fan, Yong, Sun, Yao, Zhang, Fan
Format: Journal Article
Language:English
Published: Germany Wiley Subscription Services, Inc 01.07.2019
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ISSN:2192-2640, 2192-2659, 2192-2659
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Abstract In vivo second near‐infrared (NIR‐II, 1.0–1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scattering. In the course of preclinical practices, organic and inorganic emitters with NIR‐II signals are indispensable keys to open the invisible biological window. In this review, NIR‐II emitters, including but not limited to organic emitters like organic small molecules and copolymers, and inorganic emitters such as lanthanide‐based nanocrystals, quantum dots like Ag2S dots, and carbon nanotubes, are described, especially regarding their unique optical features and noteworthy functions for animal bioimaging. Along with these existing advances, the challenges and potential spaces for further progress are discussed to offer an approximate direction for future researches. In vivo second near‐infrared bioimaging is of great importance to provide precise information with high temporal and spatial resolution and deeper penetration depth. In this mini review, NIR‐II contrast agents including organic and inorganic materials are described with respective features and unique optical functions for animal bioimaging. Later, the challenges and potential spaces for further progress are also discussed.
AbstractList In vivo second near‐infrared (NIR‐II, 1.0–1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scattering. In the course of preclinical practices, organic and inorganic emitters with NIR‐II signals are indispensable keys to open the invisible biological window. In this review, NIR‐II emitters, including but not limited to organic emitters like organic small molecules and copolymers, and inorganic emitters such as lanthanide‐based nanocrystals, quantum dots like Ag 2 S dots, and carbon nanotubes, are described, especially regarding their unique optical features and noteworthy functions for animal bioimaging. Along with these existing advances, the challenges and potential spaces for further progress are discussed to offer an approximate direction for future researches.
In vivo second near-infrared (NIR-II, 1.0-1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scattering. In the course of preclinical practices, organic and inorganic emitters with NIR-II signals are indispensable keys to open the invisible biological window. In this review, NIR-II emitters, including but not limited to organic emitters like organic small molecules and copolymers, and inorganic emitters such as lanthanide-based nanocrystals, quantum dots like Ag S dots, and carbon nanotubes, are described, especially regarding their unique optical features and noteworthy functions for animal bioimaging. Along with these existing advances, the challenges and potential spaces for further progress are discussed to offer an approximate direction for future researches.
In vivo second near-infrared (NIR-II, 1.0-1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scattering. In the course of preclinical practices, organic and inorganic emitters with NIR-II signals are indispensable keys to open the invisible biological window. In this review, NIR-II emitters, including but not limited to organic emitters like organic small molecules and copolymers, and inorganic emitters such as lanthanide-based nanocrystals, quantum dots like Ag2 S dots, and carbon nanotubes, are described, especially regarding their unique optical features and noteworthy functions for animal bioimaging. Along with these existing advances, the challenges and potential spaces for further progress are discussed to offer an approximate direction for future researches.In vivo second near-infrared (NIR-II, 1.0-1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scattering. In the course of preclinical practices, organic and inorganic emitters with NIR-II signals are indispensable keys to open the invisible biological window. In this review, NIR-II emitters, including but not limited to organic emitters like organic small molecules and copolymers, and inorganic emitters such as lanthanide-based nanocrystals, quantum dots like Ag2 S dots, and carbon nanotubes, are described, especially regarding their unique optical features and noteworthy functions for animal bioimaging. Along with these existing advances, the challenges and potential spaces for further progress are discussed to offer an approximate direction for future researches.
In vivo second near‐infrared (NIR‐II, 1.0–1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scattering. In the course of preclinical practices, organic and inorganic emitters with NIR‐II signals are indispensable keys to open the invisible biological window. In this review, NIR‐II emitters, including but not limited to organic emitters like organic small molecules and copolymers, and inorganic emitters such as lanthanide‐based nanocrystals, quantum dots like Ag2S dots, and carbon nanotubes, are described, especially regarding their unique optical features and noteworthy functions for animal bioimaging. Along with these existing advances, the challenges and potential spaces for further progress are discussed to offer an approximate direction for future researches.
In vivo second near‐infrared (NIR‐II, 1.0–1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance to afford precise dynamic actions in vivo with high spatiotemporal resolution, deeper penetration, and decreasing light absorption and scattering. In the course of preclinical practices, organic and inorganic emitters with NIR‐II signals are indispensable keys to open the invisible biological window. In this review, NIR‐II emitters, including but not limited to organic emitters like organic small molecules and copolymers, and inorganic emitters such as lanthanide‐based nanocrystals, quantum dots like Ag2S dots, and carbon nanotubes, are described, especially regarding their unique optical features and noteworthy functions for animal bioimaging. Along with these existing advances, the challenges and potential spaces for further progress are discussed to offer an approximate direction for future researches. In vivo second near‐infrared bioimaging is of great importance to provide precise information with high temporal and spatial resolution and deeper penetration depth. In this mini review, NIR‐II contrast agents including organic and inorganic materials are described with respective features and unique optical functions for animal bioimaging. Later, the challenges and potential spaces for further progress are also discussed.
Author Ding, Feng
Sun, Yao
Fan, Yong
Zhang, Fan
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/30983165$$D View this record in MEDLINE/PubMed
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Issue 14
Keywords organic and inorganic emitters
second near-infrared channel
photoacoustic imaging
fluorescence imaging
Language English
License 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Snippet In vivo second near‐infrared (NIR‐II, 1.0–1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance...
In vivo second near-infrared (NIR-II, 1.0-1.7 µm) bioimaging , a rapidly expanding imaging tool for preclinical diagnosis and prognosis, is of great importance...
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StartPage e1900260
SubjectTerms Carbon nanotubes
Electromagnetic absorption
Emitters
fluorescence imaging
Medical imaging
Nanocrystals
Nanotubes
organic and inorganic emitters
photoacoustic imaging
Quantum dots
second near‐infrared channel
Title Beyond 1000 nm Emission Wavelength: Recent Advances in Organic and Inorganic Emitters for Deep‐Tissue Molecular Imaging
URI https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fadhm.201900260
https://www.ncbi.nlm.nih.gov/pubmed/30983165
https://www.proquest.com/docview/2263212991
https://www.proquest.com/docview/2210000238
Volume 8
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