Real-world survival and prognostic factors in WHO 2021 classified gliomas treated with chemo-radiotherapy

The 2021 WHO glioma classification integrates molecular profiling, but outcome data for these patients are limited. We retrospectively analyzed 179 patients (median age 53) with WHO 2021-classified gliomas (grade 2: n = 45, grade 3: n = 51, grade 4: n = 83) treated with surgery and radio(chemo)thera...

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Published in:	Scientific reports Vol. 15; no. 1; pp. 38011 - 15
Main Authors:	Bilski, Mateusz, Noël, Georges, Smółka, Krzysztof, Kuncewicz, Katarzyna, Kuźnicki, Wojciech, Feuvret, Loic, Korab, Katarzyna, Peszyńska-Piorun, Magdalena, Korona, Paweł, Baranowska, Izabela, Suleja, Agata, Le Fevre, Clara, Schott, Roland, Somme, Laura, Chabli, Salma, Mesny, Emmanuel, Mastroleo, Federico, Kotecha, Rupesh, Jurkiewicz, Jakub, Fijuth, Jacek, Jereczek-Fossa, Barbara Alicja, Krystkiewicz, Kamil, Harat, Maciej, Kuncman, Łukasz
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 30.10.2025 Nature Publishing Group Nature Portfolio
Subjects:	631/67 692/4028 Adult Aged Brain cancer Brain Neoplasms - genetics Brain Neoplasms - mortality Brain Neoplasms - pathology Brain Neoplasms - therapy Cell number Chemoradiotherapy - methods Chemotherapy Classification Clinical outcomes Female France Glioma Glioma - classification Glioma - genetics Glioma - mortality Glioma - pathology Glioma - therapy Humanities and Social Sciences Humans Isocitrate Dehydrogenase - genetics Leukopenia Lymphocytes Male Medical prognosis Middle Aged multidisciplinary Mutation Neoplasm Grading Poland Prognosis Radiation therapy Retrospective Studies Science Science (multidisciplinary) Steroids Survival Survival analysis Variables World Health Organization Young Adult Poland France
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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