Comparative risk of end-stage renal disease, myocardial infarction and stroke in young and older onset diabetes in UK Biobank

In recent years, coinciding with the increasing incidence of type 2 diabetes mellitus (T2DM) in children and adolescents, the global prevalence of diabetic kidney disease (DKD) and end-stage renal disease (ESRD) are rising year on year. In contrast, the mortality and morbidity due to cardiovascular...

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Bibliographic Details
Published in:	Scientific reports Vol. 15; no. 1; pp. 39073 - 13
Main Authors:	Kar, Debasish, Molokhia, Mariam, Wierzbicki, Anthony, Koziell, Ania, Byng, Richard, Spicer, Stuart, Farina, Nicolas, Pinkney, Jonathan, Song, Soon, Zabeen, Bedowra, Kar, Shubharthi, Jonnagaddala, Jitendra, Liaw, Siaw-Teng, El-Wazir, Aya, Nath, Mintu, Khan, Moien A. B., Sheikh, Aziz, de Lusignan, Simon
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 07.11.2025 Nature Publishing Group Nature Portfolio
Subjects:	692/163 692/4022 Adult Age Age of Onset Aged Angina Angina pectoris Biobanks Biological Specimen Banks Cardiovascular disease Cardiovascular diseases Cerebral infarction Cohort analysis Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - epidemiology Diagnosis End-stage renal disease Female Heart attacks Humanities and Social Sciences Humans Hypertension Insulin Kidney diseases Kidney Failure, Chronic - epidemiology Kidney Failure, Chronic - etiology Male Metabolism Middle Aged Morbidity Mortality multidisciplinary Myocardial infarction Myocardial Infarction - epidemiology Myocardial Infarction - etiology Myocardial infarction and stroke Questionnaires Regression analysis Retrospective Studies Risk Factors Science Science (multidisciplinary) Sensitivity analysis Statistical analysis Stroke Stroke - epidemiology Stroke - etiology Tumor necrosis factor-TNF UK Biobank United Kingdom - epidemiology Variables Young Adult Young-onset diabetes Young-onset hypertension United Kingdom United Kingdom > UK Myocardial infarction and stroke End-stage renal disease Cardiovascular disease Young-onset hypertension Young-onset diabetes
ISSN:	2045-2322, 2045-2322
Online Access:	Get full text
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