Detection of lung dysfunction using ventilation and perfusion SPECT in a mouse model of chronic cigarette smoke exposure

Chronic obstructive pulmonary disease is a leading cause of morbidity and mortality worldwide. Exposure to cigarette smoke (CS) is a major risk factor for developing this chronic airflow impairment, but the early progression of disease is not well defined or understood. Ventilation/perfusion (V/Q) S...

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Vydáno v:	The Journal of nuclear medicine (1978) Ročník 54; číslo 4; s. 616
Hlavní autoři:	Jobse, Brian N, Rhem, Rod G, Wang, Iris Q, Counter, William B, Stämpfli, Martin R, Labiris, N Renée
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.04.2013
Témata:	Animals Disease Models, Animal Female Lung - diagnostic imaging Lung - physiopathology Mice Mice, Inbred BALB C Models, Animal Pulmonary Disease, Chronic Obstructive - diagnostic imaging Pulmonary Disease, Chronic Obstructive - physiopathology Smoking - adverse effects Time Factors Tomography, Emission-Computed, Single-Photon Ventilation-Perfusion Ratio
ISSN:	1535-5667, 1535-5667
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