Generation of induced pluripotent stem cells as a potential source of hematopoietic stem cells for transplant in PNH patients

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia caused by lack of CD55 and CD59 on blood cell membrane leading to increased sensitivity of blood cells to complement. Hematopoietic stem cell transplantation (HSCT) is the only curative therapy for PNH, however, lack of HLA-ma...

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Veröffentlicht in:	Annals of hematology Jg. 95; H. 10; S. 1617 - 1625
Hauptverfasser:	Phondeechareon, Tanapol, Wattanapanitch, Methichit, U-pratya, Yaowalak, Damkham, Chanapa, Klincumhom, Nuttha, Lorthongpanich, Chanchao, Kheolamai, Pakpoom, Laowtammathron, Chuti, Issaragrisil, Surapol
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin/Heidelberg Springer Berlin Heidelberg 01.10.2016 Springer Nature B.V
Schlagworte:	Animals Antigens, CD34 - biosynthesis CD55 Antigens - biosynthesis CD59 Antigens - biosynthesis Cellular Reprogramming Techniques Embryoid Bodies Female Fibroblasts - cytology Hematology Hematopoietic Stem Cell Transplantation Hemoglobinuria, Paroxysmal - therapy History, 16th Century History, 17th Century Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - transplantation Leukosialin - biosynthesis Medicine Medicine & Public Health Mice, Inbred BALB C Mice, Nude Oncology Original Article Skin - cytology Teratoma - pathology Transplantation, Autologous Hematopoietic cell differentiation Paroxysmal nocturnal hemoglobinuria Induced pluripotent stem cells Hematopoietic stem cells
ISSN:	0939-5555, 1432-0584, 1432-0584
Online-Zugang:	Volltext
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