Artificial neural networks analysis of surface-enhanced laser desorption/ionization mass spectra of serum protein pattern distinguishes colorectal cancer from healthy population

The low specificity and sensitivity of the carcinoembryonic antigen test makes it not an ideal biomarker for the detection of colorectal cancer. We developed and evaluated a proteomic approach for the simultaneous detection and analysis of multiple proteins for distinguishing individuals with colore...

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Bibliographic Details
Published in:	Clinical cancer research Vol. 10; no. 24; p. 8380
Main Authors:	Chen, Yi-ding, Zheng, Shu, Yu, Jie-kai, Hu, Xun
Format:	Journal Article
Language:	English
Published:	United States 15.12.2004
Subjects:	Adult Aged Aged, 80 and over Biomarkers, Tumor - metabolism Blood Proteins - analysis CA-19-9 Antigen - metabolism Case-Control Studies Colorectal Neoplasms - blood Diagnosis, Differential Female Humans Male Middle Aged Neural Networks (Computer) Protein Array Analysis Sensitivity and Specificity Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods
ISSN:	1078-0432
Online Access:	Get more information
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