Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians

Autoimmune thyroid diseases (AITD) are multifactorial endocrine diseases most frequently accompanied by Tg and TPO autoantibodies. Both antibodies have a higher prevalence in females and act under a strong genetic influence. To identify novel variants underlying thyroid antibody levels, we performed...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Jg. 111; H. 4; S. 737 - 743
Hauptverfasser:	Matana, Antonela, Popović, Marijana, Boutin, Thibaud, Torlak, Vesela, Brdar, Dubravka, Gunjača, Ivana, Kolčić, Ivana, Boraska Perica, Vesna, Punda, Ante, Polašek, Ozren, Hayward, Caroline, Barbalić, Maja, Zemunik, Tatijana
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.07.2019
Schlagworte:	Adult autoantibodies Autoantibodies - blood Autoantibodies - immunology bivariate analysis Calcium-Binding Proteins - genetics Croatia Female females gender differences Genome-wide association study Humans Iodide Peroxidase - immunology loci Male Membrane Proteins - genetics Meta-analysis Middle Aged Polymorphism, Single Nucleotide Receptors, N-Methyl-D-Aspartate - genetics Sex Factors Single nucleotide polymorphism Thyroglobulin Thyroglobulin - immunology Thyroid antibody thyroid diseases Thyroid peroxidase Thyroiditis, Autoimmune - genetics Croatia Thyroid antibody Single nucleotide polymorphism Genome-wide association study Thyroglobulin Thyroid peroxidase Meta-analysis
ISSN:	0888-7543, 1089-8646, 1089-8646
Online-Zugang:	Volltext
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