Nucleoside-modified mRNA vaccination partially overcomes maternal antibody inhibition of de novo immune responses in mice

Maternal antibodies provide short-term protection to infants against many infections. However, they can inhibit de novo antibody responses in infants elicited by infections or vaccination, leading to increased long-term susceptibility to infectious diseases. Thus, there is a need to develop vaccines...

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Veröffentlicht in:Science translational medicine Jg. 12; H. 525
Hauptverfasser: Willis, Elinor, Pardi, Norbert, Parkhouse, Kaela, Mui, Barbara L, Tam, Ying K, Weissman, Drew, Hensley, Scott E
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 08.01.2020
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ISSN:1946-6242, 1946-6242
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