De novo CpG island methylation in human cancer cells

A major obstacle toward understanding how patterns of abnormal mammalian cytosine DNA methylation are established is the difficulty in quantitating the de novo methylation activities of DNA methyltransferases (DNMT) thought to catalyze these reactions. Here, we describe a novel method, using native...

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Vydané v:	Cancer research (Chicago, Ill.) Ročník 66; číslo 2; s. 682
Hlavní autori:	Jair, Kam-Wing, Bachman, Kurtis E, Suzuki, Hiromu, Ting, Angela H, Rhee, Ina, Yen, Ray-Whay Chiu, Baylin, Stephen B, Schuebel, Kornel E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.01.2006
Predmet:	Animals Colonic Neoplasms - genetics Colonic Neoplasms - pathology CpG Islands DNA (Cytosine-5-)-Methyltransferase 1 DNA (Cytosine-5-)-Methyltransferases - physiology DNA Methylation Drosophila - genetics Genetic Engineering Humans Tumor Cells, Cultured
ISSN:	0008-5472
On-line prístup:	Zistit podrobnosti o prístupe
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