De novo CpG island methylation in human cancer cells

A major obstacle toward understanding how patterns of abnormal mammalian cytosine DNA methylation are established is the difficulty in quantitating the de novo methylation activities of DNA methyltransferases (DNMT) thought to catalyze these reactions. Here, we describe a novel method, using native...

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Bibliographic Details

Published in:	Cancer research (Chicago, Ill.) Vol. 66; no. 2; p. 682
Main Authors:	Jair, Kam-Wing, Bachman, Kurtis E, Suzuki, Hiromu, Ting, Angela H, Rhee, Ina, Yen, Ray-Whay Chiu, Baylin, Stephen B, Schuebel, Kornel E
Format:	Journal Article
Language:	English
Published:	United States 15.01.2006
Subjects:	Animals Colonic Neoplasms - genetics Colonic Neoplasms - pathology CpG Islands DNA (Cytosine-5-)-Methyltransferase 1 DNA (Cytosine-5-)-Methyltransferases - physiology DNA Methylation Drosophila - genetics Genetic Engineering Humans Tumor Cells, Cultured
ISSN:	0008-5472
Online Access:	Get more information
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