Non-spherical polymersomes: formation and characterization

Polymersomes are self-assembled hollow membrane sacs that are not only able to encapsulate hydrophobic and/or hydrophilic molecules, but also possess exceptional chemical and physical stability, structural versatility, and surface modifiability. For the above reasons, polymersomes have in recent yea...

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Vydané v:Chemical Society reviews Ročník 48; číslo 15; s. 4019
Hlavní autori: Wong, Chin Ken, Stenzel, Martina H, Thordarson, Pall
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: England 29.07.2019
ISSN:1460-4744, 1460-4744
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Shrnutí:Polymersomes are self-assembled hollow membrane sacs that are not only able to encapsulate hydrophobic and/or hydrophilic molecules, but also possess exceptional chemical and physical stability, structural versatility, and surface modifiability. For the above reasons, polymersomes have in recent years emerged as a powerful tool for a wide range of applications in the fields of biomimicry and drug delivery. The full potential of polymersomes, however, has yet to be harnessed due to a lack of appreciation of existing shape control methods. This very much contrasts the field of inorganic nanoparticle synthesis where non-spherical hollow metal nanoparticles are routinely prepared and used. Here, we summarize recent efforts over the past decade to study the morphological transformation of conventionally spherical polymersomes into non-spherical polymersomes.
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ISSN:1460-4744
1460-4744
DOI:10.1039/c8cs00856f