Quantitative MRI volumetry, diffusivity, cerebrovascular flow, and cranial hydrodynamics during head-down tilt and hypercapnia: the SPACECOT study

To improve the pathophysiological understanding of visual changes observed in astronauts, we aimed to use quantitative MRI to measure anatomic and physiological responses during a ground-based spaceflight analog (head-down tilt, HDT) combined with increased ambient carbon dioxide (CO ). Six healthy,...

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Bibliographic Details
Published in:	Journal of applied physiology (1985) Vol. 122; no. 5; pp. 1155 - 1166
Main Authors:	Kramer, Larry A, Hasan, Khader M, Sargsyan, Ashot E, Marshall-Goebel, Karina, Rittweger, Jörn, Donoviel, Dorit, Higashi, Saki, Mwangi, Benson, Gerlach, Darius A, Bershad, Eric M
Format:	Journal Article
Language:	English
Published:	United States 01.05.2017
Subjects:	Adult Carbon Dioxide Carotid Arteries - physiology Cerebrospinal Fluid - physiology Cerebrovascular Circulation - physiology Cross-Over Studies Double-Blind Method Head-Down Tilt - physiology Humans Hydrodynamics Hypercapnia - physiopathology Magnetic Resonance Imaging - methods Male Space Flight - methods intracranial hypertension microgravity space analog head-down tilt dMRI hypercapnia
ISSN:	1522-1601
Online Access:	Get more information
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