OATP1B3-1B7, a novel organic anion transporting polypeptide, is modulated by FXR ligands and transports bile acids

Organic anion transporting polypeptide (OATP) 1B3-1B7 (LST-3TM12) is a member of the OATP1B [solute carrier organic anion transporter ( ) ] family. This transporter is not only functional but also expressed in the membrane of the smooth endoplasmic reticulum of hepatocytes and enterocytes. OATP1B3-1...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology Jg. 317; H. 6; S. G751
Hauptverfasser:	Malagnino, Vanessa, Hussner, Janine, Issa, Ali, Midzic, Angela, Meyer Zu Schwabedissen, Henriette E
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.12.2019
Schlagworte:	Antineoplastic Agents - pharmacology Bile Acids and Salts - physiology Biological Transport - physiology Gene Expression Regulation Gene Regulatory Networks - physiology HeLa Cells Hep G2 Cells Humans Isoxazoles - pharmacology Organic Anion Transporters - genetics Organic Anion Transporters - metabolism Receptors, Cytoplasmic and Nuclear - agonists Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors Receptors, Cytoplasmic and Nuclear - genetics Solute Carrier Organic Anion Transporter Family Member 1B3 - genetics Solute Carrier Organic Anion Transporter Family Member 1B3 - metabolism Solute Carrier Proteins - genetics Solute Carrier Proteins - metabolism Transcription Factors Transcriptional Activation LST-3TM12 SLCO1B7 farnesoid X receptor OATP1B3-1B7 SLCO1B3
ISSN:	1522-1547, 1522-1547
Online-Zugang:	Weitere Angaben
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