miRNA in multiple sclerosis: search for novel biomarkers

A major challenge in multiple sclerosis (MS) is to develop biomarkers that could help in understanding individual MS patients, i.e. whether they are a responder or non-responder to therapy, which medicine is more effective, and the degree to which they may be entering the progressive phase of diseas...

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Bibliographic Details
Published in:Multiple sclerosis Vol. 21; no. 9; pp. 1095 - 1103
Main Author: Gandhi, Roopali
Format: Journal Article
Language:English
Published: London, England SAGE Publications 01.08.2015
Sage Publications Ltd
Subjects:
Animals
Biomarkers - analysis
Humans
MicroRNAs - genetics
Multiple Sclerosis - genetics
miRNAs
biomarkers
multiple sclerosis
ISSN:1352-4585, 1477-0970
Online Access:Get full text
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Summary:A major challenge in multiple sclerosis (MS) is to develop biomarkers that could help in understanding individual MS patients, i.e. whether they are a responder or non-responder to therapy, which medicine is more effective, and the degree to which they may be entering the progressive phase of disease. In the last few years, a lot of attention has been drawn toward identification of diagnostic, prognostic, process-specific, and treatment-related biomarkers for MS. In this review, we will focus on the micro RNAs (miRNAs) as potential candidates for MS biomarkers.
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ISSN:1352-4585
1477-0970
DOI:10.1177/1352458515578771