The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential

Voltage-gated calcium channels are required for many key functions in the body. In this review, the different subtypes of voltage-gated calcium channels are described and their physiologic roles and pharmacology are outlined. We describe the current uses of drugs interacting with the different calci...

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Veröffentlicht in:	Pharmacological reviews Jg. 67; H. 4; S. 821
Hauptverfasser:	Zamponi, Gerald W, Striessnig, Joerg, Koschak, Alexandra, Dolphin, Annette C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands 01.10.2015
Schlagworte:	Calcium Channel Blockers - pharmacology Calcium Channels - classification Calcium Channels - genetics Calcium Channels - pharmacology Calcium Channels - physiology Calcium Channels, L-Type - pharmacology Calcium Channels, L-Type - physiology Calcium Channels, N-Type - pharmacology Calcium Channels, N-Type - physiology Calcium Channels, T-Type - pharmacology Calcium Channels, T-Type - physiology Cardiovascular Diseases - physiopathology Cyclic AMP-Dependent Protein Kinases - metabolism GTP-Binding Proteins - metabolism Hearing Disorders - physiopathology Humans Metabolic Diseases - physiopathology Nervous System Diseases - physiopathology Night Blindness - physiopathology Phospholipids - metabolism Receptor Protein-Tyrosine Kinases - metabolism
ISSN:	1521-0081, 1521-0081
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