Severe acute respiratory syndrome and the innate immune responses: modulation of effector cell function without productive infection

Severe acute respiratory syndrome (SARS) caused by a novel human coronavirus (CoV), designated SARS-CoV, is a highly contagious respiratory disease with the lungs as a major target. Although the exact mechanism of SARS-CoV pathogenesis remains unknown, an intense, ill-regulated local inflammatory re...

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Bibliographic Details
Published in:	The Journal of immunology (1950) Vol. 174; no. 12; p. 7977
Main Authors:	Tseng, Chien-Te K, Perrone, Lucy A, Zhu, Hongbing, Makino, Shinji, Peters, Clarence J
Format:	Journal Article
Language:	English
Published:	United States 15.06.2005
Subjects:	Cell Death - immunology Cell Differentiation - immunology Cell Line Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism Dendritic Cells - virology Disease Susceptibility Endocytosis - immunology Humans Immunity, Cellular Immunity, Innate Immunophenotyping Interleukin-12 - biosynthesis Interleukin-6 - biosynthesis Lectins, C-Type - antagonists & inhibitors Lectins, C-Type - physiology Lymphocyte Activation - immunology Macrophages - cytology Macrophages - immunology Macrophages - metabolism Macrophages - virology Mannose-Binding Lectins - antagonists & inhibitors Mannose-Binding Lectins - physiology Receptors, Cell Surface - antagonists & inhibitors Receptors, Cell Surface - physiology SARS Virus - immunology SARS Virus - pathogenicity Severe Acute Respiratory Syndrome - immunology U937 Cells
ISSN:	0022-1767
Online Access:	Get more information
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