The Effect of Dabigatran on Select Specialty Coagulation Assays

Dabigatran etexilate is a new oral anticoagulant that functions as a direct thrombin inhibitor. An inhibitor of thrombin has the potential to interfere with essentially all clot-based coagulation assays and select chromogenic assays, whereas the drug would not be expected to interfere in antigen-bas...

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Bibliographic Details
Published in:	American journal of clinical pathology Vol. 139; no. 1; pp. 102 - 109
Main Authors:	Adcock, Dorothy M., Gosselin, Robert, Kitchen, Steve, Dwyre, Denis M.
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.01.2013
Subjects:	Activated Protein C Resistance - blood Administration, Oral Antithrombins - pharmacology Benzimidazoles - pharmacology Blood Coagulation - drug effects Blood Coagulation Tests Dabigatran Diagnostic Errors Factor VIII - analysis False Positive Reactions Humans In Vitro Techniques Partial Thromboplastin Time - methods Protein S Deficiency - blood Prothrombin - analysis Pyridines - pharmacology Thrombin - antagonists & inhibitors
ISSN:	0002-9173, 1943-7722, 1943-7722
Online Access:	Get full text
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