Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial pain

•Cannabidiol and cannabinol alone and in combination reversed masseter muscle sensitization in a behavioral model of temporomandibular disorders.•Both cannabinoids decreased the mechanical sensitivity of masseter muscle afferent fibers.•Though not as effective as delta-9-tetrahydrocannabinol, these...

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Bibliographic Details
Published in:	Archives of oral biology Vol. 104; pp. 33 - 39
Main Authors:	Wong, Hayes, Cairns, Brian E.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.08.2019
Subjects:	Analgesics - pharmacology Animals Cannabichromene Cannabidiol Cannabidiol - pharmacology Cannabinoid receptors Cannabinol Cannabinol - pharmacology Disease Models, Animal Female Masseter muscle Myofascial Pain Syndromes - drug therapy Nerve growth factor Rats CBD CBC Masseter muscle GPR Cannabidiol Nerve growth factor TMD NGF CBN THC Cannabinol Cannabichromene Cannabinoid receptors
ISSN:	0003-9969, 1879-1506, 1879-1506
Online Access:	Get full text
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