Cannabidiol, cannabinol and their combinations act as peripheral analgesics in a rat model of myofascial pain

•Cannabidiol and cannabinol alone and in combination reversed masseter muscle sensitization in a behavioral model of temporomandibular disorders.•Both cannabinoids decreased the mechanical sensitivity of masseter muscle afferent fibers.•Though not as effective as delta-9-tetrahydrocannabinol, these...

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Vydané v:	Archives of oral biology Ročník 104; s. 33 - 39
Hlavní autori:	Wong, Hayes, Cairns, Brian E.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Elsevier Ltd 01.08.2019
Predmet:	Analgesics - pharmacology Animals Cannabichromene Cannabidiol Cannabidiol - pharmacology Cannabinoid receptors Cannabinol Cannabinol - pharmacology Disease Models, Animal Female Masseter muscle Myofascial Pain Syndromes - drug therapy Nerve growth factor Rats CBD CBC Masseter muscle GPR Cannabidiol Nerve growth factor TMD NGF CBN THC Cannabinol Cannabichromene Cannabinoid receptors
ISSN:	0003-9969, 1879-1506, 1879-1506
On-line prístup:	Získať plný text
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