Photodynamic therapy mediated by aluminium-phthalocyanine nanoemulsion eliminates primary tumors and pulmonary metastases in a murine 4T1 breast adenocarcinoma model

Photodynamic therapy (PDT) is effective in the treatment of different types of cancer, such as basal cell carcinoma and other superficial cancers. However, improvements in photosensitizer delivery are still needed, and the use of PDT against more deeply located tumors has been the subject of many st...

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Bibliographic Details
Published in:	Journal of photochemistry and photobiology. B, Biology Vol. 204; p. 111808
Main Authors:	Rodrigues, Mosar Corrêa, Vieira, Lívia Gumieri, Horst, Frederíco Hillesheim, de Araújo, Eduarda Campos, Ganassin, Rayane, Merker, Carolin, Meyer, Thomas, Böttner, Julia, Venus, Tom, Longo, João Paulo F., Chaves, Sacha Braun, Garcia, Mônica Pereira, Estrela-Lopis, Irina, Azevedo, Ricardo Bentes, Muehlmann, Luis Alexandre
Format:	Journal Article
Language:	English
Published:	Switzerland Elsevier B.V 01.03.2020 Elsevier BV
Subjects:	Abscopal Adenocarcinoma Adenocarcinoma - diagnostic imaging Adenocarcinoma - drug therapy Adenocarcinoma - pathology Aluminum Aluminum - chemistry Animals Basal cell carcinoma Breast Breast cancer breast neoplasms Breast Neoplasms - diagnostic imaging Breast Neoplasms - drug therapy Breast Neoplasms - pathology breasts Callipers Cancer Cell Line, Tumor Cell Survival - drug effects Emulsions Evaluation Female histology histopathology Indoles - chemistry Lung Neoplasms - diagnostic imaging Lung Neoplasms - drug therapy Lung Neoplasms - secondary Lungs Metastases Metastasis Mice Mice, Inbred BALB C Microtomography Nanoemulsions Nanostructures - chemistry Nanostructures - therapeutic use Nanostructures - toxicity Nanotechnology Photochemotherapy Photodynamic therapy Photosensitizer photosensitizing agents Photosensitizing Agents - chemistry Photosensitizing Agents - therapeutic use Photosensitizing Agents - toxicity Reactive Oxygen Species - metabolism Robust control Transplantation, Homologous Tumors X-Ray Microtomography Photosensitizer Nanotechnology Abscopal Cancer
ISSN:	1011-1344, 1873-2682, 1873-2682
Online Access:	Get full text
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