TFOFinder: Python program for identifying purine-only double-stranded stretches in the predicted secondary structure(s) of RNA targets

Nucleic acid probes are valuable tools in biology and chemistry and are indispensable for PCR amplification of DNA, RNA quantification and visualization, and downregulation of gene expression. Recently, triplex-forming oligonucleotides (TFO) have received increased attention due to their improved se...

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Bibliographic Details
Published in:	PLoS computational biology Vol. 19; no. 8; p. e1011418
Main Authors:	Neugroschl, Atara, Catrina, Irina E.
Format:	Journal Article
Language:	English
Published:	San Francisco Public Library of Science 01.08.2023 Public Library of Science (PLoS)
Subjects:	Algorithms Biology and life sciences Catalysis Deoxyribonucleic acid Design DNA DNA probes Double-stranded RNA Gene expression Genomes Helices Influenza Influenza A Inversions Medicine and health sciences MicroRNAs Nucleic acids Nucleotides Oligonucleotides Peptide nucleic acids Peptides Physical Sciences Polyamines Probes Protein structure Purines Replication Research and Analysis Methods Ribonucleic acid RNA RNA probes Secondary structure Structure Target recognition Transcriptomes United States
ISSN:	1553-7358, 1553-734X, 1553-7358
Online Access:	Get full text
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