TFOFinder: Python program for identifying purine-only double-stranded stretches in the predicted secondary structure(s) of RNA targets

Nucleic acid probes are valuable tools in biology and chemistry and are indispensable for PCR amplification of DNA, RNA quantification and visualization, and downregulation of gene expression. Recently, triplex-forming oligonucleotides (TFO) have received increased attention due to their improved se...

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Vydáno v:	PLoS computational biology Ročník 19; číslo 8; s. e1011418
Hlavní autoři:	Neugroschl, Atara, Catrina, Irina E.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	San Francisco Public Library of Science 01.08.2023 Public Library of Science (PLoS)
Témata:	Algorithms Biology and life sciences Catalysis Deoxyribonucleic acid Design DNA DNA probes Double-stranded RNA Gene expression Genomes Helices Influenza Influenza A Inversions Medicine and health sciences MicroRNAs Nucleic acids Nucleotides Oligonucleotides Peptide nucleic acids Peptides Physical Sciences Polyamines Probes Protein structure Purines Replication Research and Analysis Methods Ribonucleic acid RNA RNA probes Secondary structure Structure Target recognition Transcriptomes United States
ISSN:	1553-7358, 1553-734X, 1553-7358
On-line přístup:	Získat plný text
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