Ion channel model reduction using manifold boundaries

Mathematical models of voltage-gated ion channels are used in basic research, industrial and clinical settings. These models range in complexity, but typically contain numerous variables representing the proportion of channels in a given state, and parameters describing the voltage-dependent rates o...

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Vydané v:	Journal of the Royal Society interface Ročník 19; číslo 193; s. 20220193
Hlavní autori:	Whittaker, Dominic G, Wang, Jiahui, Shuttleworth, Joseph G, Venkateshappa, Ravichandra, Kemp, Jacob M, Claydon, Thomas W, Mirams, Gary R
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 10.08.2022
Predmet:	ERG1 Potassium Channel - genetics Ether-A-Go-Go Potassium Channels Heart HEK293 Cells Humans Ion Channels mathematical model model reduction electrophysiology ion channel identifiability
ISSN:	1742-5662, 1742-5662
On-line prístup:	Zistit podrobnosti o prístupe
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