Treatment of psoriasis with etanercept in immunocompromised patients: Two case reports
Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant tre...
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| Published in: | Journal of international medical research Vol. 44; no. 1_suppl; pp. 67 - 71 |
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| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
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SAGE Publications
01.09.2016
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| ISSN: | 0300-0605, 1473-2300, 1473-2300 |
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| Abstract | Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF-α agent, without notable side-effects. |
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| AbstractList | Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF-α agent, without notable side-effects. Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF-α agent, without notable side-effects.Tumour necrosis factor (TNF)-α blocking agents have revolutionized the treatment of psoriasis and psoriatic arthritis. Concerns remain about increased susceptibility to infection and onset of malignancies, and the use of TNF-α agents in patients with HIV infection or undergoing immunosuppressant treatment is debated. We report cases of severe plaque psoriasis in a patient with HIV infection and in a liver transplant recipient who were successfully treated with etanercept, an anti-TNF-α agent, without notable side-effects. |
| Author | De Simone, Clara Perino, Francesca Caldarola, Giacomo D’Agostino, Magda Peris, Ketty |
| AuthorAffiliation | Department of Dermatology, Catholic University of the Sacred Heart, Rome, Italy |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27683143$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1111/j.1365-4632.2005.02642.x 10.1016/j.transproceed.2012.09.008 10.1016/S1473-3099(10)70101-8 10.1097/TP.0b013e3182247b5f 10.1371/journal.pone.0042011 10.1159/000250839 10.1016/j.jaad.2009.03.047 10.1016/j.jbspin.2006.05.012 10.1136/ard.2007.081513 10.1007/s40257-013-0053-5 10.1111/bjd.12326 10.1517/13543784.2012.669372 |
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| Keywords | Antitumour necrosis factor-α agents psoriatic arthritis comorbidities etanercept psoriasis |
| Language | English |
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| Title | Treatment of psoriasis with etanercept in immunocompromised patients: Two case reports |
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