Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors

Several studies have reported reprogramming of fibroblasts into induced cardiomyocytes; however, reprogramming into proliferative induced cardiac progenitor cells (iCPCs) remains to be accomplished. Here we report that a combination of 11 or 5 cardiac factors along with canonical Wnt and JAK/STAT si...

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Bibliographic Details

Published in:	Cell stem cell Vol. 18; no. 3; p. 354
Main Authors:	Lalit, Pratik A, Salick, Max R, Nelson, Daryl O, Squirrell, Jayne M, Shafer, Christina M, Patel, Neel G, Saeed, Imaan, Schmuck, Eric G, Markandeya, Yogananda S, Wong, Rachel, Lea, Martin R, Eliceiri, Kevin W, Hacker, Timothy A, Crone, Wendy C, Kyba, Michael, Garry, Daniel J, Stewart, Ron, Thomson, James A, Downs, Karen M, Lyons, Gary E, Kamp, Timothy J
Format:	Journal Article
Language:	English
Published:	United States 03.03.2016
Subjects:	Animals Cell Proliferation Cell Survival Cellular Reprogramming Cellular Reprogramming Techniques - methods Fibroblasts - cytology Fibroblasts - metabolism Mice Mice, Transgenic Myoblasts, Cardiac - cytology Myoblasts, Cardiac - metabolism Transcription Factors - biosynthesis Transcription Factors - genetics
ISSN:	1875-9777, 1875-9777
Online Access:	Get more information
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