Regioselectivity in the ring opening of non-activated aziridines
In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship between the observed regioselectivity and inherent structural features such as the nature of the C2 aziridine substituen...
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| Vydané v: | Chemical Society reviews Ročník 41; číslo 2; s. 643 |
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| Hlavní autori: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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21.01.2012
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| ISSN: | 1460-4744, 1460-4744 |
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| Abstract | In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship between the observed regioselectivity and inherent structural features such as the nature of the C2 aziridine substituent and the nature of the electrophile and the nucleophile. This overview should allow chemists to gain insight into the factors governing the regioselectivity in aziridinium ring openings (81 references). |
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| AbstractList | In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship between the observed regioselectivity and inherent structural features such as the nature of the C2 aziridine substituent and the nature of the electrophile and the nucleophile. This overview should allow chemists to gain insight into the factors governing the regioselectivity in aziridinium ring openings (81 references).In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship between the observed regioselectivity and inherent structural features such as the nature of the C2 aziridine substituent and the nature of the electrophile and the nucleophile. This overview should allow chemists to gain insight into the factors governing the regioselectivity in aziridinium ring openings (81 references). In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship between the observed regioselectivity and inherent structural features such as the nature of the C2 aziridine substituent and the nature of the electrophile and the nucleophile. This overview should allow chemists to gain insight into the factors governing the regioselectivity in aziridinium ring openings (81 references). |
| Author | De Kimpe, Norbert Ha, Hyun-Joon Eum, Heesung Stanković, Sonja Catak, Saron Waroquier, Michel D'hooghe, Matthias Van Speybroeck, Veronique |
| Author_xml | – sequence: 1 givenname: Sonja surname: Stanković fullname: Stanković, Sonja organization: Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium – sequence: 2 givenname: Matthias surname: D'hooghe fullname: D'hooghe, Matthias – sequence: 3 givenname: Saron surname: Catak fullname: Catak, Saron – sequence: 4 givenname: Heesung surname: Eum fullname: Eum, Heesung – sequence: 5 givenname: Michel surname: Waroquier fullname: Waroquier, Michel – sequence: 6 givenname: Veronique surname: Van Speybroeck fullname: Van Speybroeck, Veronique – sequence: 7 givenname: Norbert surname: De Kimpe fullname: De Kimpe, Norbert – sequence: 8 givenname: Hyun-Joon surname: Ha fullname: Ha, Hyun-Joon |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21894345$$D View this record in MEDLINE/PubMed |
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