Study of concentration of amniotic fluid Alpha-fetal protein in thalassemia fetus
Objective:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein(AFAFP) is increased in thalassemia fetus.Methods:A total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study.Among them 98 cases of normal fetuses were assigned in...
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| Vydané v: | Asian Pacific journal of tropical medicine Ročník 10; číslo 2; s. 192 - 194 |
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| Hlavní autori: | , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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India
Elsevier B.V
01.02.2017
Department of Obstetrics and Gynecology, Souther Hospital, Affiliated Hospital of Southern Medical University, Guangzhou 510515 China%Department of Obstetrics, Prenatal Diagnose Center, Affiliated Hospital of Hainan Medical University, Haikou Hainan 570011 China |
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| ISSN: | 1995-7645, 2352-4146 |
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| Abstract | Objective:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein(AFAFP) is increased in thalassemia fetus.Methods:A total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study.Among them 98 cases of normal fetuses were assigned into control group and 37 cases of thalassemia fetus were included as thalassemia fetus group.Alpha-fetoprotein levels detected by enzyme linked immunosorbent assay and the alpha-fetoprotein concentration were compared between the two groups.There is no significant difference in gestrational age between the two groups.Results:1.AFP concentration in thalassemia fetus group was significantly higher than that of normal control group [(1541.65±734.78) μg/mL vs.(2728.84± 1539.97) μg/mL ],and amniotic fluid AFP concentration was related to fetal thalassemia.2.AFAFP concentration in pureα-thalassemia fetus was higher than that of β thalassemia fetus or mixed αand was not significant.Conclusions:Concentration of a β thalassemia fetus,but the difference mniotic fluid alpha-fetal protein is increased in thalassemia fetus.AFP concentration inα-thalassemia fetus was higher than that of β thalassemia or mixed αand lore β thalassemia fetus but difference was not significance.Further studies are needed to exp the possible correlation between Down syndrome and biochemical markers of Thalassemia. |
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| AbstractList | Objective:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein(AFAFP) is increased in thalassemia fetus.Methods:A total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study.Among them 98 cases of normal fetuses were assigned into control group and 37 cases of thalassemia fetus were included as thalassemia fetus group.Alpha-fetoprotein levels detected by enzyme linked immunosorbent assay and the alpha-fetoprotein concentration were compared between the two groups.There is no significant difference in gestrational age between the two groups.Results:1.AFP concentration in thalassemia fetus group was significantly higher than that of normal control group [(1541.65±734.78) μg/mL vs.(2728.84± 1539.97) μg/mL ],and amniotic fluid AFP concentration was related to fetal thalassemia.2.AFAFP concentration in pureα-thalassemia fetus was higher than that of β thalassemia fetus or mixed αand was not significant.Conclusions:Concentration of a β thalassemia fetus,but the difference mniotic fluid alpha-fetal protein is increased in thalassemia fetus.AFP concentration inα-thalassemia fetus was higher than that of β thalassemia or mixed αand lore β thalassemia fetus but difference was not significance.Further studies are needed to exp the possible correlation between Down syndrome and biochemical markers of Thalassemia. To test the hypothesis that concentration of amniotic fluid alpha-fetal protein (AFAFP) is increased in thalassemia fetus. A total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study. Among them 98 cases of normal fetuses were assigned into control group and 37 cases of thalassemia fetus were included as thalassemia fetus group. Alpha-fetoprotein levels detected by enzyme linked immunosorbent assay and the alpha-fetoprotein concentration were compared between the two groups. There is no significant difference in gestational age between the two groups. 1. AFP concentration in thalassemia fetus group was significantly higher than that of normal control group [(1541.65 ± 734.78) μg/mL vs. (2728.84 ± 1539.97) μg/mL], and amniotic fluid AFP concentration was related to fetal thalassemia. 2. AFAFP concentration in pure α-thalassemia fetus was higher than that of β-thalassemia fetus or mixed α- and β-thalassemia fetus, but the difference was not significant. Concentration of amniotic fluid alpha-fetal protein is increased in thalassemia fetus. AFP concentration in α-thalassemia fetus was higher than that of β-thalassemia or mixed α- and β-thalassemia fetus but difference was not significance. Further studies are needed to explore the possible correlation between Down syndrome and biochemical markers of thalassemia. Objective:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein(AFAFP) is increased in thalassemia fetus.Methods: A total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study. Among them 98 cases of normal fetuses were assigned into control group and 37 cases of thalassemia fetus were included as thalassemia fetus group. Alpha-fetoprotein levels detected by enzyme linked immunosorbent assay and the alpha-fetoprotein concentration were compared between the two groups. There is no significant difference in gestrational age between the two groups. Results: 1. AFP concentration in thalassemia fetus group was significantly higher than that of normal control group [(1541.65±734.78) μg/mLvs. (2728.84± 1539.97) μg/mL], and amniotic fluid AFP concentration was related to fetal thalassemia. 2. AFAFP concentration in pure -thalassemia fetus was higher than that ofβthalassemia fetus or mixed and βthalassemia fetus, but the difference was not significant.Conclusions: Concentration of amniotic fluid alpha-fetal protein is increased in thalassemia fetus. AFP concentration in -thalassemia fetus was higher than that of βthalassemia or mixed and βthalassemia fetus but difference was not significance. Further studies are needed to explore the possible correlation between Down syndrome and biochemical markers of Thalassemia. OBJECTIVESTo test the hypothesis that concentration of amniotic fluid alpha-fetal protein (AFAFP) is increased in thalassemia fetus.METHODSA total of 135 cases of amniocentesis admitted from July 2013 to December 2014 were included in this study. Among them 98 cases of normal fetuses were assigned into control group and 37 cases of thalassemia fetus were included as thalassemia fetus group. Alpha-fetoprotein levels detected by enzyme linked immunosorbent assay and the alpha-fetoprotein concentration were compared between the two groups. There is no significant difference in gestational age between the two groups.RESULTS1. AFP concentration in thalassemia fetus group was significantly higher than that of normal control group [(1541.65 ± 734.78) μg/mL vs. (2728.84 ± 1539.97) μg/mL], and amniotic fluid AFP concentration was related to fetal thalassemia. 2. AFAFP concentration in pure α-thalassemia fetus was higher than that of β-thalassemia fetus or mixed α- and β-thalassemia fetus, but the difference was not significant.CONCLUSIONSConcentration of amniotic fluid alpha-fetal protein is increased in thalassemia fetus. AFP concentration in α-thalassemia fetus was higher than that of β-thalassemia or mixed α- and β-thalassemia fetus but difference was not significance. Further studies are needed to explore the possible correlation between Down syndrome and biochemical markers of thalassemia. |
| Author | Yi Ling Yan-Hong Yu Song Jin Chun-Xia Hu Wei Peng Hong-Yu Zhang Huo Fu Ning Zhang Yan-Xin Wei Ze-Jun Chen |
| AuthorAffiliation | Department of Obstetrics and Gynecology,Souther Hospital,Affiliated Hospital of Southern Medical University;Department of Obstetrics,Prenatal Diagnose Center,Affiliated Hospital of Hainan Medical University |
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| Keywords | Thalassemia Fetus Amniotic fluid Alpha-fetoprotein |
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| References | Bartha, Harrison, Kyle, Soothill (bib12) 2003; 23 Tikkanen, Hämäläinen, Nuutila, Paavonen, Ylikorkala, Hiilesmaa (bib7) 2007; 27 Nishie, Brizot, Liao, Carvalho, Toma, Zugaib (bib10) 2003; 188 Bartha, Omar, Soothill (bib1) 2004; 24 Slavotinek, Kaylor, Pierce, Cahr, DeWard Stephanie, Schneidman-Duhovny (bib2) 2015; 96 Rood, Stiller (bib4) 2013; 77 Yoon, Kang, Jin, Park, Rho (bib3) 2014; 57 Lubuský, Procházka, Santavý, Mícková, Kantor (bib8) 2006; 71 Zimmerman, Carpenter, Durig, Mari (bib9) 2002; 109 Alvarez-Nava, Soto, Lanes, Pons, Morales-Machin, Bracho (bib13) 2015; 41 Bartha, Illanes, Abdel-Fattah, Harrison, Soothill (bib6) 2006; 26 Scheier, Hernandez-Andrade, Carmo, Dezerega, Nicolaides (bib11) 2004; 23 Slavotinek (10.1016/j.apjtm.2017.01.001_bib2) 2015; 96 Yoon (10.1016/j.apjtm.2017.01.001_bib3) 2014; 57 Bartha (10.1016/j.apjtm.2017.01.001_bib12) 2003; 23 Tikkanen (10.1016/j.apjtm.2017.01.001_bib7) 2007; 27 Lubuský (10.1016/j.apjtm.2017.01.001_bib8) 2006; 71 Nishie (10.1016/j.apjtm.2017.01.001_bib10) 2003; 188 Alvarez-Nava (10.1016/j.apjtm.2017.01.001_bib13) 2015; 41 Rood (10.1016/j.apjtm.2017.01.001_bib4) 2013; 77 Zimmerman (10.1016/j.apjtm.2017.01.001_bib9) 2002; 109 Scheier (10.1016/j.apjtm.2017.01.001_bib11) 2004; 23 Bartha (10.1016/j.apjtm.2017.01.001_bib6) 2006; 26 Bartha (10.1016/j.apjtm.2017.01.001_bib1) 2004; 24 |
| References_xml | – volume: 41 start-page: 1891 year: 2015 end-page: 1898 ident: bib13 article-title: Elevated second-trimester maternal serum β-human chorionic gonadotropin and amniotic fluid alpha-fetoprotein as indicators of adverse obstetric outcomes in fetal Turner syndrome publication-title: J Obstet Gynaecol Res – volume: 57 start-page: 223 year: 2014 end-page: 227 ident: bib3 article-title: A meningomyelocele with normal intracranial signs on ultrasound and false-negative amniotic fluidalpha-fetoprotein and acetylcholinesterase publication-title: Obstet Gynecol Sci – volume: 77 start-page: 43 year: 2013 end-page: 45 ident: bib4 article-title: Hereditary persistence of alpha-fetoprotein: a rare cause for unexplained alpha-fetoprotein elevations in pregnancy publication-title: Conn Med – volume: 188 start-page: 214 year: 2003 end-page: 219 ident: bib10 article-title: A comparison between middle cerebral artery peak systolic velocity and amniotic fluid optical density at 450 nm in the prediction of fetal anemia publication-title: Am J Obstet Gynecol – volume: 109 start-page: 746 year: 2002 end-page: 752 ident: bib9 article-title: Longitudinal measurement of peak systolic velocity in the fetal middle cerebral artery for monitoring pregnancies complicated by red cell alloimmunisation: a prospective multicentre trial with intention-to-treat publication-title: BJOG – volume: 23 start-page: 432 year: 2004 end-page: 436 ident: bib11 article-title: Prediction of fetal anemia in rhesus disease by measurement of fetal middle cerebral artery peak systolic velocity publication-title: Ultrasound Obstet Gynecol – volume: 96 start-page: 162 year: 2015 end-page: 169 ident: bib2 article-title: CRB2 mutations produce a phenotype resembling congenital nephrosis, Finnish type, with cerebral ventriculomegaly and raised alpha-fetoprotein publication-title: Am J Hum Genet – volume: 71 start-page: 272 year: 2006 end-page: 280 ident: bib8 article-title: Actual management of pregnancies at risk for fetal anemia publication-title: Ceska Gynekol – volume: 23 start-page: 917 year: 2003 end-page: 920 ident: bib12 article-title: Fetal serum alpha-fetoprotein in alloimmunised pregnancies publication-title: Prenat Diagn – volume: 24 start-page: 609 year: 2004 end-page: 612 ident: bib1 article-title: The relationship between maternal serum alpha-fetoprotein and maternal haemoglobin publication-title: Prenat Diagn – volume: 27 start-page: 240 year: 2007 end-page: 243 ident: bib7 article-title: Elevated maternal second-trimester serum alpha-fetoprotein as a risk factor for placental abruption publication-title: Prenat Diagn – volume: 26 start-page: 101 year: 2006 end-page: 104 ident: bib6 article-title: Maternal serum alpha-fetoprotein, fetal middle cerebral artery blood flow velocity and fetal haemoglobin in pregnancies at risk of fetal anaemia publication-title: Prenat Diagn – volume: 96 start-page: 162 issue: 1 year: 2015 ident: 10.1016/j.apjtm.2017.01.001_bib2 article-title: CRB2 mutations produce a phenotype resembling congenital nephrosis, Finnish type, with cerebral ventriculomegaly and raised alpha-fetoprotein publication-title: Am J Hum Genet doi: 10.1016/j.ajhg.2014.11.013 – volume: 23 start-page: 432 issue: 5 year: 2004 ident: 10.1016/j.apjtm.2017.01.001_bib11 article-title: Prediction of fetal anemia in rhesus disease by measurement of fetal middle cerebral artery peak systolic velocity publication-title: Ultrasound Obstet Gynecol doi: 10.1002/uog.1010 – volume: 27 start-page: 240 issue: 3 year: 2007 ident: 10.1016/j.apjtm.2017.01.001_bib7 article-title: Elevated maternal second-trimester serum alpha-fetoprotein as a risk factor for placental abruption publication-title: Prenat Diagn doi: 10.1002/pd.1654 – volume: 77 start-page: 43 issue: 1 year: 2013 ident: 10.1016/j.apjtm.2017.01.001_bib4 article-title: Hereditary persistence of alpha-fetoprotein: a rare cause for unexplained alpha-fetoprotein elevations in pregnancy publication-title: Conn Med – volume: 26 start-page: 101 issue: 2 year: 2006 ident: 10.1016/j.apjtm.2017.01.001_bib6 article-title: Maternal serum alpha-fetoprotein, fetal middle cerebral artery blood flow velocity and fetal haemoglobin in pregnancies at risk of fetal anaemia publication-title: Prenat Diagn doi: 10.1002/pd.1351 – volume: 109 start-page: 746 issue: 7 year: 2002 ident: 10.1016/j.apjtm.2017.01.001_bib9 article-title: Longitudinal measurement of peak systolic velocity in the fetal middle cerebral artery for monitoring pregnancies complicated by red cell alloimmunisation: a prospective multicentre trial with intention-to-treat publication-title: BJOG doi: 10.1111/j.1471-0528.2002.01314.x – volume: 41 start-page: 1891 issue: 12 year: 2015 ident: 10.1016/j.apjtm.2017.01.001_bib13 article-title: Elevated second-trimester maternal serum β-human chorionic gonadotropin and amniotic fluid alpha-fetoprotein as indicators of adverse obstetric outcomes in fetal Turner syndrome publication-title: J Obstet Gynaecol Res doi: 10.1111/jog.12813 – volume: 24 start-page: 609 issue: 8 year: 2004 ident: 10.1016/j.apjtm.2017.01.001_bib1 article-title: The relationship between maternal serum alpha-fetoprotein and maternal haemoglobin publication-title: Prenat Diagn doi: 10.1002/pd.921 – volume: 23 start-page: 917 issue: 11 year: 2003 ident: 10.1016/j.apjtm.2017.01.001_bib12 article-title: Fetal serum alpha-fetoprotein in alloimmunised pregnancies publication-title: Prenat Diagn doi: 10.1002/pd.728 – volume: 71 start-page: 272 issue: 4 year: 2006 ident: 10.1016/j.apjtm.2017.01.001_bib8 article-title: Actual management of pregnancies at risk for fetal anemia publication-title: Ceska Gynekol – volume: 57 start-page: 223 issue: 3 year: 2014 ident: 10.1016/j.apjtm.2017.01.001_bib3 article-title: A meningomyelocele with normal intracranial signs on ultrasound and false-negative amniotic fluidalpha-fetoprotein and acetylcholinesterase publication-title: Obstet Gynecol Sci doi: 10.5468/ogs.2014.57.3.223 – volume: 188 start-page: 214 issue: 1 year: 2003 ident: 10.1016/j.apjtm.2017.01.001_bib10 article-title: A comparison between middle cerebral artery peak systolic velocity and amniotic fluid optical density at 450 nm in the prediction of fetal anemia publication-title: Am J Obstet Gynecol doi: 10.1067/mob.2003.63 |
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| Snippet | Objective:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein(AFAFP) is increased in thalassemia fetus.Methods:A total of 135 cases... To test the hypothesis that concentration of amniotic fluid alpha-fetal protein (AFAFP) is increased in thalassemia fetus. A total of 135 cases of... OBJECTIVESTo test the hypothesis that concentration of amniotic fluid alpha-fetal protein (AFAFP) is increased in thalassemia fetus.METHODSA total of 135 cases... Objective:To test the hypothesis that concentration of amniotic fluid alpha-fetal protein(AFAFP) is increased in thalassemia fetus.Methods: A total of 135... |
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| SubjectTerms | Alpha-fetoprotein Amniotic fluid Fetus Thalassemia |
| Title | Study of concentration of amniotic fluid Alpha-fetal protein in thalassemia fetus |
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