Lipid and Carbohydrate Metabolism in Caenorhabditis elegans

Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutri...

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Veröffentlicht in:Genetics (Austin) Jg. 207; H. 2; S. 413 - 446
Hauptverfasser: Watts, Jennifer L, Ristow, Michael
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Genetics Society of America 01.10.2017
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ISSN:1943-2631, 0016-6731, 1943-2631
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Abstract Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.
AbstractList Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, C. elegans synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in C. elegans. We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.
Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, C. elegans synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in C. elegans We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, C. elegans synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in C. elegans We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.
Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.
Author Watts, Jennifer L
Ristow, Michael
Author_xml – sequence: 1
  givenname: Jennifer L
  orcidid: 0000-0003-4349-0639
  surname: Watts
  fullname: Watts, Jennifer L
  email: jwatts@vetmed.wsu.edu
  organization: School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington 99164 jwatts@vetmed.wsu.edu
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  givenname: Michael
  surname: Ristow
  fullname: Ristow, Michael
  organization: Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, 8603 Schwerzenbach-Zurich, Switzerland
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Copyright Copyright © 2017 by the Genetics Society of America.
Copyright Genetics Society of America Oct 2017
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Keywords Caenorhabditis elegans
glucose
fatty acids
sphingolipids
cholesterol
triacylglycerols
ascarosides
phospholipids
maradolipids
WormBook
Language English
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Snippet Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. eat bacteria, which consist of lipids,...
Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. Caenorhabditis elegans eat bacteria,...
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SubjectTerms Amino acids
Animals
Bacteria
Biosynthesis
Caenorhabditis elegans
Caenorhabditis elegans - genetics
Caenorhabditis elegans - metabolism
Carbohydrate Metabolism
Carbohydrates
Environmental changes
Environmental conditions
Fatty acids
Genetics
Genomics
Lipid Metabolism
Lipids
Metabolism
Metabolism, Physiology, and Aging
Metabolites
Nematodes
Nutrients
Proteins
Sugar
WormBook
Worms
Title Lipid and Carbohydrate Metabolism in Caenorhabditis elegans
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