TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives

Triggering receptor expressed on myeloid cells-1 (TREM-1) is expressed on the majority of innate immune cells and to a lesser extent on parenchymal cells. Upon activation, TREM-1 can directly amplify an inflammatory response. Although it was initially demonstrated that TREM-1 was predominantly assoc...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Pharmacology & therapeutics (Oxford) Jg. 177; S. 81 - 95
Hauptverfasser:	Tammaro, Alessandra, Derive, Marc, Gibot, Sebastien, Leemans, Jaklien C., Florquin, Sandrine, Dessing, Mark C.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.09.2017
Schlagworte:	Animals Humans Inflammation - drug therapy Inflammation - metabolism Ligands Signal Transduction Triggering Receptor Expressed on Myeloid Cells-1 - antagonists & inhibitors Triggering Receptor Expressed on Myeloid Cells-1 - genetics Triggering Receptor Expressed on Myeloid Cells-1 - metabolism TREM-1 ligands TREM-1 inhibitors Non-infectious inflammatory diseases Triggering receptor expressed on myeloid cells-1 TLR/NLR pathway
ISSN:	0163-7258, 1879-016X, 1879-016X
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!