Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure

Patients with diabetes and recent worsening heart failure that had led to hospitalization were randomly assigned to receive sotagliflozin or placebo. At a median of 9 months, the total number of deaths from cardiovascular causes and hospitalizations and urgent visits for heart failure was significan...

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 384; no. 2; pp. 117 - 128
Main Authors:	Bhatt, Deepak L, Szarek, Michael, Steg, P. Gabriel, Cannon, Christopher P, Leiter, Lawrence A, McGuire, Darren K, Lewis, Julia B, Riddle, Matthew C, Voors, Adriaan A, Metra, Marco, Lund, Lars H, Komajda, Michel, Testani, Jeffrey M, Wilcox, Christopher S, Ponikowski, Piotr, Lopes, Renato D, Verma, Subodh, Lapuerta, Pablo, Pitt, Bertram
Format:	Journal Article
Language:	English
Published:	United States Massachusetts Medical Society 14.01.2021
Subjects:	Acute Kidney Injury - chemically induced Aged Cardiac arrhythmia Cardiovascular Diseases - epidemiology Cardiovascular Diseases - mortality Congestive heart failure Corporate sponsorship Death Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Diarrhea Diuretics Double-Blind Method Ejection fraction Female Glucose Glycosides - adverse effects Glycosides - therapeutic use Heart failure Heart Failure - complications Heart Failure - drug therapy Hospitalization Hospitalization - statistics & numerical data Humans Hypoglycemia Hypotension Hypotension - chemically induced Male Middle Aged Peptides Placebos Sodium-glucose cotransporter Sodium-Glucose Transporter 1 - antagonists & inhibitors Sodium-Glucose Transporter 2 Inhibitors - adverse effects Sodium-Glucose Transporter 2 Inhibitors - therapeutic use Statistical analysis North America Europe Latin America
ISSN:	0028-4793, 1533-4406, 1533-4406
Online Access:	Get full text
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