Type 1 diabetes: etiology, immunology, and therapeutic strategies

Type 1 diabetes (T1D) is a chronic autoimmune disease in which destruction or damaging of the beta-cells in the islets of Langerhans results in insulin deficiency and hyperglycemia. We only know for sure that autoimmunity is the predominant effector mechanism of T1D, but may not be its primary cause...

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Bibliographic Details

Published in:	Physiological reviews Vol. 91; no. 1; p. 79
Main Authors:	van Belle, Tom L, Coppieters, Ken T, von Herrath, Matthias G
Format:	Journal Article
Language:	English
Published:	United States 01.01.2011
Subjects:	Animals Clinical Trials as Topic Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - therapy Genetic Predisposition to Disease Humans Prediabetic State - diagnosis Primary Prevention
ISSN:	1522-1210, 1522-1210
Online Access:	Get more information
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