Capsular polysaccharide types of group B streptococcal isolates from neonates with early-onset systemic infection

The distribution of serotypes of group B streptococci (GBS) isolated from 67 infants with early-onset sepsis are described. Case-infants were assembled from 13 hospitals across the United States from 15 July 1995 to 5 February 1997 through prospective active surveillance. The distribution of GBS ser...

Full description

Saved in:

Bibliographic Details
Published in:	The Journal of infectious diseases Vol. 177; no. 3; p. 790
Main Authors:	Lin, F Y, Clemens, J D, Azimi, P H, Regan, J A, Weisman, L E, Philips, 3rd, J B, Rhoads, G G, Clark, P, Brenner, R A, Ferrieri, P
Format:	Journal Article
Language:	English
Published:	United States 01.03.1998
Subjects:	Bacterial Capsules - classification Bacterial Capsules - immunology Humans Infant, Newborn Prospective Studies Sepsis - microbiology Serotyping Streptococcal Infections - microbiology Streptococcus agalactiae - classification Streptococcus agalactiae - immunology
ISSN:	0022-1899
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Abstract	The distribution of serotypes of group B streptococci (GBS) isolated from 67 infants with early-onset sepsis are described. Case-infants were assembled from 13 hospitals across the United States from 15 July 1995 to 5 February 1997 through prospective active surveillance. The distribution of GBS serotypes was Ia, 40%; Ib, 9%; II, 6%; III, 27%; V, 15%; and nontypeable, 3%. Type V occurred more frequently in the northeast region (New York and New Jersey) than in other regions (29% vs. 9%, P = .06). Conversely, type III occurred significantly less frequently in the northeast region than other regions (10% vs. 35%, P = .04). GBS types Ia, III, and V accounted for 82% of the isolates. This report supports previous observations about the emergence of GBS type V, but our data caution that conclusions about serotype distributions based on one geographic location or on a small number of patients may not be generally applicable. Continued monitoring seems necessary for the design of a GBS vaccine.
AbstractList	The distribution of serotypes of group B streptococci (GBS) isolated from 67 infants with early-onset sepsis are described. Case-infants were assembled from 13 hospitals across the United States from 15 July 1995 to 5 February 1997 through prospective active surveillance. The distribution of GBS serotypes was Ia, 40%; Ib, 9%; II, 6%; III, 27%; V, 15%; and nontypeable, 3%. Type V occurred more frequently in the northeast region (New York and New Jersey) than in other regions (29% vs. 9%, P = .06). Conversely, type III occurred significantly less frequently in the northeast region than other regions (10% vs. 35%, P = .04). GBS types Ia, III, and V accounted for 82% of the isolates. This report supports previous observations about the emergence of GBS type V, but our data caution that conclusions about serotype distributions based on one geographic location or on a small number of patients may not be generally applicable. Continued monitoring seems necessary for the design of a GBS vaccine.The distribution of serotypes of group B streptococci (GBS) isolated from 67 infants with early-onset sepsis are described. Case-infants were assembled from 13 hospitals across the United States from 15 July 1995 to 5 February 1997 through prospective active surveillance. The distribution of GBS serotypes was Ia, 40%; Ib, 9%; II, 6%; III, 27%; V, 15%; and nontypeable, 3%. Type V occurred more frequently in the northeast region (New York and New Jersey) than in other regions (29% vs. 9%, P = .06). Conversely, type III occurred significantly less frequently in the northeast region than other regions (10% vs. 35%, P = .04). GBS types Ia, III, and V accounted for 82% of the isolates. This report supports previous observations about the emergence of GBS type V, but our data caution that conclusions about serotype distributions based on one geographic location or on a small number of patients may not be generally applicable. Continued monitoring seems necessary for the design of a GBS vaccine. The distribution of serotypes of group B streptococci (GBS) isolated from 67 infants with early-onset sepsis are described. Case-infants were assembled from 13 hospitals across the United States from 15 July 1995 to 5 February 1997 through prospective active surveillance. The distribution of GBS serotypes was Ia, 40%; Ib, 9%; II, 6%; III, 27%; V, 15%; and nontypeable, 3%. Type V occurred more frequently in the northeast region (New York and New Jersey) than in other regions (29% vs. 9%, P = .06). Conversely, type III occurred significantly less frequently in the northeast region than other regions (10% vs. 35%, P = .04). GBS types Ia, III, and V accounted for 82% of the isolates. This report supports previous observations about the emergence of GBS type V, but our data caution that conclusions about serotype distributions based on one geographic location or on a small number of patients may not be generally applicable. Continued monitoring seems necessary for the design of a GBS vaccine.
Author	Philips, 3rd, J B Lin, F Y Clemens, J D Azimi, P H Clark, P Regan, J A Ferrieri, P Brenner, R A Rhoads, G G Weisman, L E
Author_xml	– sequence: 1 givenname: F Y surname: Lin fullname: Lin, F Y organization: National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA – sequence: 2 givenname: J D surname: Clemens fullname: Clemens, J D – sequence: 3 givenname: P H surname: Azimi fullname: Azimi, P H – sequence: 4 givenname: J A surname: Regan fullname: Regan, J A – sequence: 5 givenname: L E surname: Weisman fullname: Weisman, L E – sequence: 6 givenname: J B surname: Philips, 3rd fullname: Philips, 3rd, J B – sequence: 7 givenname: G G surname: Rhoads fullname: Rhoads, G G – sequence: 8 givenname: P surname: Clark fullname: Clark, P – sequence: 9 givenname: R A surname: Brenner fullname: Brenner, R A – sequence: 10 givenname: P surname: Ferrieri fullname: Ferrieri, P
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/9498466$$D View this record in MEDLINE/PubMed
BookMark	eNotkM1KxDAYRbMYGcdR30DIyl01SdMmXergHwy40XVJky9OJG06SYr07S06q8uBw-VyL9BqCAMgdE3JHSWyvq-okJSs0IYQxgoqm-YcXaT0TQjhZS3WaN3wRvK63qDjTo1p8iriMfg5Ka0PKjoDOM8jJBws_ophGvEjTjnCmIMOWiuPXQpe5cWwMfR4gDD80Y_LBwwq-rkIQ4KM05wy9E5jN1jQ2YXhEp1Z5RNcnXKLPp-fPnavxf795W33sC80ZzIXpiplJ4mxRlkjxQKipLI0DTessZQZqK3WHeEVEYJQDQJ0JShnoiREdx3botv_3jGG4wQpt71LGrxXy9optaIRrJRELOLNSZy6Hkw7RterOLenj9gvrJVphA
CitedBy_id	crossref_primary_10_1128_JCM_37_11_3759_3760_1999 crossref_primary_10_1128_JCM_39_12_4526_4528_2001 crossref_primary_10_1586_14760584_5_5_687 crossref_primary_10_1016_j_vaccine_2006_07_018 crossref_primary_10_1097_00006454_199904000_00022 crossref_primary_10_1053_siny_2002_0114 crossref_primary_10_1128_IAI_67_12_6350_6357_1999 crossref_primary_10_1128_IAI_67_5_2491_2496_1999 crossref_primary_10_1111_j_1469_0691_2004_00931_x crossref_primary_10_1186_s12879_019_3809_6 crossref_primary_10_1073_pnas_182380799 crossref_primary_10_1086_313665 crossref_primary_10_1128_IAI_71_12_6857_6863_2003 crossref_primary_10_1016_j_ajpath_2015_05_015 crossref_primary_10_1016_S0264_410X_00_00226_7 crossref_primary_10_1093_aje_kwj075 crossref_primary_10_1097_00006454_199909000_00012 crossref_primary_10_1007_PL00012158 crossref_primary_10_1016_j_gene_2016_10_030 crossref_primary_10_1128_JCM_43_12_5899_5906_2005 crossref_primary_10_1128_IAI_68_10_5610_5618_2000 crossref_primary_10_1016_j_jmii_2011_01_003 crossref_primary_10_1128_JCM_41_6_2659_2661_2003 crossref_primary_10_1016_S1045_1870_99_80041_7 crossref_primary_10_1128_AAC_45_11_3205_3208_2001 crossref_primary_10_1046_j_1469_0691_2000_00007_x crossref_primary_10_1128_IAI_70_2_803_811_2002 crossref_primary_10_1128_IAI_72_8_4716_4722_2004 crossref_primary_10_1046_j_1440_1754_2002_00783_x crossref_primary_10_1086_427942 crossref_primary_10_3928_0090_4481_19980801_08 crossref_primary_10_1128_JB_182_16_4466_4477_2000 crossref_primary_10_1128_JCM_02105_07 crossref_primary_10_1371_journal_pone_0204617 crossref_primary_10_1128_JCM_37_8_2564_2567_1999 crossref_primary_10_1128_JCM_40_1_216_226_2002 crossref_primary_10_1016_S1286_4579_00_01328_9 crossref_primary_10_1073_pnas_0506758102 crossref_primary_10_1097_00006454_200109000_00011 crossref_primary_10_1542_peds_104_2_203 crossref_primary_10_1097_00006454_200004000_00022 crossref_primary_10_3947_ic_2024_0127 crossref_primary_10_1093_infdis_jit549 crossref_primary_10_1128_IAI_73_3_1671_1683_2005 crossref_primary_10_1128_JCM_44_4_1257_1261_2006 crossref_primary_10_1128_CMR_18_1_102_127_2005 crossref_primary_10_1128_IAI_70_11_6409_6415_2002
ContentType	Journal Article
DBID	CGR CUY CVF ECM EIF NPM 7X8
DOI	10.1086/517810
DatabaseName	Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic
DatabaseTitle	MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic
DatabaseTitleList	MEDLINE - Academic MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database
DeliveryMethod	no_fulltext_linktorsrc
Discipline	Medicine Biology
ExternalDocumentID	9498466
Genre	Multicenter Study Research Support, U.S. Gov't, P.H.S Journal Article
GrantInformation_xml	– fundername: NICHD NIH HHS grantid: HD-43214 – fundername: NICHD NIH HHS grantid: HD-43215 – fundername: NICHD NIH HHS grantid: HD-43217
GroupedDBID	--- -DZ -~X ..I .2P .55 .GJ .I3 .XZ .ZR 08P 0R~ 123 1KJ 1TH 29K 2AX 2WC 36B 3O- 4.4 41~ 48X 53G 5GY 5RE 5VS 5WD 6.Y 70D 85S AABZA AACGO AACZT AAHBH AAHTB AAJKP AAJQQ AAMVS AANCE AAOGV AAPGJ AAPNW AAPQZ AAPXW AAQQT AARHZ AAUAY AAUQX AAVAP AAWDT AAWTL AAYOK ABBHK ABDFA ABDPE ABEJV ABEUO ABGNP ABIXL ABJNI ABKDP ABLJU ABNHQ ABNKS ABOCM ABPEJ ABPLY ABPPZ ABPTD ABQLI ABQNK ABSAR ABSMQ ABTLG ABVGC ABWST ABXSQ ABXVV ABZBJ ACFRR ACGFO ACGFS ACGOD ACHIC ACPQN ACPRK ACUFI ACUTJ ACUTO ACYHN ACZBC ADBBV ADEYI ADGZP ADHKW ADHZD ADIPN ADJQC ADOCK ADQBN ADRIX ADRTK ADULT ADVEK ADYVW ADZXQ AEGPL AEGXH AEJOX AEKPW AEKSI AEMDU AENEX AENZO AEPUE AETBJ AEUPB AEWNT AEXZC AFFNX AFFQV AFFZL AFHKK AFIYH AFOFC AFQQW AFSHK AFXAL AFXEN AFYAG AGINJ AGKEF AGKRT AGMDO AGQXC AGSYK AGUTN AHMBA AHMMS AHXPO AI. AIAGR AIJHB AJEEA ALMA_UNASSIGNED_HOLDINGS ALUQC APIBT APJGH APWMN AQDSO AQKUS AQVQM ATGXG AXUDD BAWUL BAYMD BCRHZ BEYMZ BHONS BR6 BTRTY BVRKM BZKNY C45 CDBKE CGR CS3 CUY CVF CZ4 D-I DAKXR DCCCD DIK DILTD DOOOF DU5 D~K EBS ECGQY ECM EE~ EIF EIHJH EJD EMOBN ENERS ESX F5P F9B FECEO FLUFQ FOEOM FOTVD FQBLK GAUVT GJXCC GX1 H13 H5~ HAR HQ3 HTVGU HW0 HZ~ IH2 IOX IPSME J21 J5H JAAYA JBMMH JENOY JHFFW JKQEH JLS JLXEF JPM JSG JSODD JST KAQDR KBUDW KOP KQ8 KSI KSN L7B LSO LU7 M49 MBLQV MHKGH MJL ML0 MVM N4W N9A NEJ NGC NOMLY NOYVH NPM NU- NVLIB O0~ O9- OAUYM OAWHX OCZFY ODMLO OJQWA OJZSN OK1 OPAEJ OVD OWPYF O~Y P0- P2P PAFKI PEELM PQQKQ Q1. Q5Y QBD RD5 ROX ROZ RUSNO RW1 RXO SA0 SJN TCURE TEORI TJX TMA TR2 VH1 VXZ W2D W8F WH7 X7H X7M Y6R YAYTL YIF YKOAZ YXANX ZE2 ZGI ZKG ZXP ~91 7X8 ABPQP ADNBA ADQXQ AEMQT AJBYB AJNCP ALXQX JXSIZ
ID	FETCH-LOGICAL-c428t-d538b80dfdafd8738b73183d94d29f12de6fccb04507701ce7ec571427300cbb2
IEDL.DBID	7X8
ISICitedReferencesCount	68
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000072159900040&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	0022-1899
IngestDate	Thu Oct 02 05:41:40 EDT 2025 Wed Feb 19 02:34:02 EST 2025
IsDoiOpenAccess	false
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	3
Language	English
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c428t-d538b80dfdafd8738b73183d94d29f12de6fccb04507701ce7ec571427300cbb2
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
OpenAccessLink	https://academic.oup.com/jid/article-pdf/177/3/790/2517268/177-3-790.pdf
PMID	9498466
PQID	79723807
PQPubID	23479
ParticipantIDs	proquest_miscellaneous_79723807 pubmed_primary_9498466
PublicationCentury	1900
PublicationDate	1998-03-01
PublicationDateYYYYMMDD	1998-03-01
PublicationDate_xml	– month: 03 year: 1998 text: 1998-03-01 day: 01
PublicationDecade	1990
PublicationPlace	United States
PublicationPlace_xml	– name: United States
PublicationTitle	The Journal of infectious diseases
PublicationTitleAlternate	J Infect Dis
PublicationYear	1998
SSID	ssj0004367
Score	1.8531905
Snippet	The distribution of serotypes of group B streptococci (GBS) isolated from 67 infants with early-onset sepsis are described. Case-infants were assembled from 13...
SourceID	proquest pubmed
SourceType	Aggregation Database Index Database
StartPage	790
SubjectTerms	Bacterial Capsules - classification Bacterial Capsules - immunology Humans Infant, Newborn Prospective Studies Sepsis - microbiology Serotyping Streptococcal Infections - microbiology Streptococcus agalactiae - classification Streptococcus agalactiae - immunology
Title	Capsular polysaccharide types of group B streptococcal isolates from neonates with early-onset systemic infection
URI	https://www.ncbi.nlm.nih.gov/pubmed/9498466 https://www.proquest.com/docview/79723807
Volume	177
WOSCitedRecordID	wos000072159900040&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText
inHoldings	1
isFullTextHit
isPrint
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LS8NAEB6qVfHio1qszz14Xcw2j01AEC0WD7b0oNBbSPYBBUlSU4X-e2fygF7Eg5fAHrIku7Oz38zufB_AbWRJwdpV3EVwyz1pXZ5YYblfGRRuiI6tSFxf5XQazufRrAP3bS0MXatsfWLlqHWuKEd-Jyt5LEc-FEtOmlF0ttoIaGxB10UgQzYt5xtc4W4gW65wgWHFhrKQL2QonN9BZbW5jA__91lHcNCASvZYW8ExdEzWg91aZnLdg71Jc4B-AstRgmExRrOsyD_WZaKo6mqhDaNUbMlyy6oyD_bEqIikWOXoL3EW2QJNlFApo3IUlhnKuWOLsrjMEEcyp1vZK1YTQy8Uay95ZafwPn5-G73wRnWBKwxFVlyjC0xDR1udWB1KbEha9zry9DCyYqhNYJVKEQo6UjpCGWmUL4U3JOZ7labDPmxneWbOgGnPs4k2iU2M8FSIXQhfBdJzlAitddMB3LSDGqNV01FFgn_wVcbtsA6gX89LXNTkG3HkRQiZgvM_X72A_bZ-0BGX0LW4nM0V7Kjv1aL8vK5sBZ_T2eQHmHbMWA
linkProvider	ProQuest
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Capsular+polysaccharide+types+of+group+B+streptococcal+isolates+from+neonates+with+early-onset+systemic+infection&rft.jtitle=The+Journal+of+infectious+diseases&rft.au=Lin%2C+F+Y&rft.au=Clemens%2C+J+D&rft.au=Azimi%2C+P+H&rft.au=Regan%2C+J+A&rft.date=1998-03-01&rft.issn=0022-1899&rft.volume=177&rft.issue=3&rft.spage=790&rft_id=info:doi/10.1086%2F517810&rft.externalDBID=NO_FULL_TEXT
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-1899&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-1899&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-1899&client=summon