Functional connectivity changes within specific networks parallel the clinical evolution of multiple sclerosis

Background: In multiple sclerosis (MS), the location of focal lesions does not always correlate with clinical symptoms, suggesting disconnection as a major pathophysiological mechanism. Resting-state (RS) functional magnetic resonance imaging (fMRI) is believed to reflect brain functional connectivi...

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Vydané v:	Multiple sclerosis Ročník 20; číslo 8; s. 1050 - 1057
Hlavní autori:	Basile, B, Castelli, M, Monteleone, F, Nocentini, U, Caltagirone, C, Centonze, D, Cercignani, M, Bozzali, M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London, England SAGE Publications 01.07.2014 Sage Publications Sage Publications Ltd
Predmet:	Adult Aged Biological and medical sciences Brain - diagnostic imaging Brain - physiopathology Brain Mapping - methods Case-Control Studies Cognition Cross-Sectional Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disability Evaluation Female Humans Immunomodulators Magnetic Resonance Imaging Male Medical sciences Middle Aged Motor Activity Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Multiple Sclerosis, Chronic Progressive - diagnostic imaging Multiple Sclerosis, Chronic Progressive - physiopathology Multiple Sclerosis, Chronic Progressive - psychology Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging Multiple Sclerosis, Relapsing-Remitting - physiopathology Multiple Sclerosis, Relapsing-Remitting - psychology Nerve Net - diagnostic imaging Nerve Net - physiopathology Neurology Neuropsychological Tests Pharmacology. Drug treatments Phenotype Sensory Thresholds Severity of Illness Index Young Adult resting-state functional magnetic resonance imaging functional connectivity secondary progressive multiple sclerosis Relapsing–remitting multiple sclerosis Nervous system diseases Multiple sclerosis Nuclear magnetic resonance imaging Inflammatory disease Central nervous system disease Relapsing-remitting multiple sclerosis Medical imagery Evolution Degenerative disease Functional imaging
ISSN:	1352-4585, 1477-0970, 1477-0970
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